NR2C2AP

 

Full name: nuclear receptor 2C2 associated protein Alias Symbol: TRA16
Type: protein-coding gene Cytoband: 19p13.11
Entrez ID: 126382 HGNC ID: HGNC:30763 Ensembl Gene: ENSG00000184162 OMIM ID: 608719
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of NR2C2AP:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NR2C2AP 126382 226839_at 0.4877 0.3244
GSE26886 NR2C2AP 126382 226839_at 0.8833 0.0006
GSE45670 NR2C2AP 126382 226839_at 0.3538 0.0149
GSE53622 NR2C2AP 126382 39364 0.4314 0.0000
GSE53624 NR2C2AP 126382 74769 0.3273 0.0000
GSE63941 NR2C2AP 126382 226839_at 1.3223 0.0001
GSE77861 NR2C2AP 126382 226839_at 0.3919 0.0071
GSE97050 NR2C2AP 126382 A_24_P126181 0.2583 0.2731
SRP007169 NR2C2AP 126382 RNAseq 0.8704 0.0560
SRP008496 NR2C2AP 126382 RNAseq 1.1290 0.0038
SRP064894 NR2C2AP 126382 RNAseq 1.1410 0.0010
SRP133303 NR2C2AP 126382 RNAseq 0.3937 0.0682
SRP159526 NR2C2AP 126382 RNAseq 0.5491 0.0489
SRP193095 NR2C2AP 126382 RNAseq 0.4739 0.0002
SRP219564 NR2C2AP 126382 RNAseq 0.5935 0.0256
TCGA NR2C2AP 126382 RNAseq 0.4051 0.0000

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by NR2C2AP expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NR2C2AP:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NR2C2AP 126382 4 5 21
GSE20123 NR2C2AP 126382 3 3 24
GSE43470 NR2C2AP 126382 2 5 36
GSE46452 NR2C2AP 126382 47 1 11
GSE47630 NR2C2AP 126382 5 8 27
GSE54993 NR2C2AP 126382 16 4 50
GSE54994 NR2C2AP 126382 6 13 34
GSE60625 NR2C2AP 126382 9 0 2
GSE74703 NR2C2AP 126382 2 3 31
GSE74704 NR2C2AP 126382 0 3 17
TCGA NR2C2AP 126382 16 10 70

Total number of gains: 110; Total number of losses: 55; Total Number of normals: 323.  

 

Somatic mutations of NR2C2AP:

 

Generating mutation plots.

 

Highly correlated genes for NR2C2AP:

 

Showing top 20/1326 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NR2C2APOSR20.79832303
NR2C2APLSM40.762367706
NR2C2APPOLA10.7526404
NR2C2APMRPL120.747029303
NR2C2APPTPRU0.738777303
NR2C2APZNF8370.735585303
NR2C2APC10orf950.724792303
NR2C2APTUBA1B0.724637404
NR2C2APHAUS80.722813707
NR2C2APMRPL40.722631606
NR2C2APTUBA1C0.72224303
NR2C2APAP2A10.72059303
NR2C2APZNF3170.720241606
NR2C2APRNPS10.719318606
NR2C2APTROAP0.715542606
NR2C2APZSCAN250.713719303
NR2C2APTOP3B0.711675404
NR2C2APFARSA0.707848707
NR2C2APKXD10.706439706
NR2C2APPLEKHH10.703876303

For details and further investigation, click here