| Full name: interleukin 3 receptor subunit alpha | Alias Symbol: CD123 | ||
| Type: protein-coding gene | Cytoband: Xp22.3 and Yp13.3 | ||
| Entrez ID: 3563 | HGNC ID: HGNC:6012 | Ensembl Gene: ENSG00000185291 | OMIM ID: 308385|430000 |
| Drug and gene relationship at DGIdb | |||
IL3RA involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04151 | PI3K-Akt signaling pathway | |
| hsa04210 | Apoptosis | |
| hsa04630 | Jak-STAT signaling pathway |
Expression of IL3RA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL3RA | 3563 | 206148_at | 0.1478 | 0.7342 | |
| GSE20347 | IL3RA | 3563 | 206148_at | 0.0352 | 0.6911 | |
| GSE23400 | IL3RA | 3563 | 206148_at | -0.0355 | 0.3249 | |
| GSE26886 | IL3RA | 3563 | 206148_at | 0.1343 | 0.2909 | |
| GSE29001 | IL3RA | 3563 | 206148_at | 0.0104 | 0.9632 | |
| GSE38129 | IL3RA | 3563 | 206148_at | -0.1033 | 0.3237 | |
| GSE45670 | IL3RA | 3563 | 206148_at | -0.0873 | 0.5641 | |
| GSE63941 | IL3RA | 3563 | 206148_at | 0.1354 | 0.3978 | |
| GSE77861 | IL3RA | 3563 | 206148_at | 0.0768 | 0.5590 | |
| GSE97050 | IL3RA | 3563 | A_32_P217750 | -0.5595 | 0.1470 | |
| SRP007169 | IL3RA | 3563 | RNAseq | 1.1570 | 0.1482 | |
| SRP008496 | IL3RA | 3563 | RNAseq | 1.4505 | 0.0071 | |
| SRP064894 | IL3RA | 3563 | RNAseq | 0.3476 | 0.1617 | |
| SRP133303 | IL3RA | 3563 | RNAseq | -0.5527 | 0.0413 | |
| SRP159526 | IL3RA | 3563 | RNAseq | 0.3719 | 0.3104 | |
| SRP193095 | IL3RA | 3563 | RNAseq | 0.6737 | 0.0007 | |
| SRP219564 | IL3RA | 3563 | RNAseq | -0.3480 | 0.5436 | |
| TCGA | IL3RA | 3563 | RNAseq | -0.2430 | 0.0939 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by IL3RA expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of IL3RA:
No record found for this gene.
Somatic mutations of IL3RA:
Generating mutation plots.
Highly correlated genes for IL3RA:
Showing top 20/453 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL3RA | NME4 | 0.82068 | 3 | 0 | 3 |
| IL3RA | NFAM1 | 0.819588 | 3 | 0 | 3 |
| IL3RA | EBF1 | 0.784435 | 3 | 0 | 3 |
| IL3RA | EEF1D | 0.763824 | 3 | 0 | 3 |
| IL3RA | LIN37 | 0.762792 | 3 | 0 | 3 |
| IL3RA | ZNF594 | 0.758341 | 3 | 0 | 3 |
| IL3RA | FIBCD1 | 0.754461 | 4 | 0 | 4 |
| IL3RA | GAL | 0.752451 | 3 | 0 | 3 |
| IL3RA | PI16 | 0.750032 | 3 | 0 | 3 |
| IL3RA | MEIS3 | 0.746394 | 3 | 0 | 3 |
| IL3RA | CLMP | 0.739609 | 3 | 0 | 3 |
| IL3RA | ISM2 | 0.737124 | 3 | 0 | 3 |
| IL3RA | ZNF579 | 0.734982 | 3 | 0 | 3 |
| IL3RA | CORO1C | 0.732359 | 3 | 0 | 3 |
| IL3RA | CALML4 | 0.730563 | 3 | 0 | 3 |
| IL3RA | TMEM98 | 0.72932 | 3 | 0 | 3 |
| IL3RA | PTDSS2 | 0.726465 | 3 | 0 | 3 |
| IL3RA | PROK2 | 0.717213 | 3 | 0 | 3 |
| IL3RA | RAPGEF1 | 0.715347 | 3 | 0 | 3 |
| IL3RA | XRRA1 | 0.711128 | 3 | 0 | 3 |
For details and further investigation, click here
