| Full name: RNA polymerase II subunit J | Alias Symbol: RPB11|hRPB14|RPB11A|RPB11m|POLR2J1 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 5439 | HGNC ID: HGNC:9197 | Ensembl Gene: ENSG00000005075 | OMIM ID: 604150 |
| Drug and gene relationship at DGIdb | |||
Expression of POLR2J:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POLR2J | 5439 | 212782_x_at | 0.3083 | 0.4407 | |
| GSE20347 | POLR2J | 5439 | 212782_x_at | 0.3004 | 0.1347 | |
| GSE23400 | POLR2J | 5439 | 212782_x_at | 0.2698 | 0.0015 | |
| GSE26886 | POLR2J | 5439 | 212782_x_at | 1.4689 | 0.0000 | |
| GSE29001 | POLR2J | 5439 | 212782_x_at | -0.1760 | 0.5583 | |
| GSE38129 | POLR2J | 5439 | 212782_x_at | 0.3671 | 0.0101 | |
| GSE45670 | POLR2J | 5439 | 212782_x_at | 0.0869 | 0.6832 | |
| GSE53622 | POLR2J | 5439 | 33421 | 0.3632 | 0.0000 | |
| GSE53624 | POLR2J | 5439 | 33421 | 0.4143 | 0.0000 | |
| GSE63941 | POLR2J | 5439 | 212782_x_at | 1.4607 | 0.0008 | |
| GSE77861 | POLR2J | 5439 | 212782_x_at | 0.3406 | 0.1240 | |
| GSE97050 | POLR2J | 5439 | A_23_P42649 | 0.2011 | 0.4333 | |
| SRP007169 | POLR2J | 5439 | RNAseq | -0.5563 | 0.1809 | |
| SRP008496 | POLR2J | 5439 | RNAseq | 0.0127 | 0.9715 | |
| SRP064894 | POLR2J | 5439 | RNAseq | 0.4647 | 0.1502 | |
| SRP133303 | POLR2J | 5439 | RNAseq | 0.6174 | 0.0000 | |
| SRP159526 | POLR2J | 5439 | RNAseq | 0.2911 | 0.1857 | |
| SRP193095 | POLR2J | 5439 | RNAseq | 0.2351 | 0.1080 | |
| SRP219564 | POLR2J | 5439 | RNAseq | 0.2882 | 0.1754 | |
| TCGA | POLR2J | 5439 | RNAseq | 0.1480 | 0.0209 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by POLR2J expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POLR2J:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POLR2J | 5439 | 13 | 0 | 17 | |
| GSE20123 | POLR2J | 5439 | 12 | 0 | 18 | |
| GSE43470 | POLR2J | 5439 | 6 | 3 | 34 | |
| GSE46452 | POLR2J | 5439 | 10 | 1 | 48 | |
| GSE47630 | POLR2J | 5439 | 7 | 3 | 30 | |
| GSE54993 | POLR2J | 5439 | 1 | 10 | 59 | |
| GSE54994 | POLR2J | 5439 | 15 | 4 | 34 | |
| GSE60625 | POLR2J | 5439 | 0 | 0 | 11 | |
| GSE74703 | POLR2J | 5439 | 6 | 2 | 28 | |
| GSE74704 | POLR2J | 5439 | 9 | 0 | 11 | |
| TCGA | POLR2J | 5439 | 53 | 6 | 37 |
Total number of gains: 132; Total number of losses: 29; Total Number of normals: 327.
Somatic mutations of POLR2J:
Generating mutation plots.
Highly correlated genes for POLR2J:
Showing top 20/1181 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POLR2J | HEXA | 0.843516 | 3 | 0 | 3 |
| POLR2J | KRTCAP2 | 0.802494 | 3 | 0 | 3 |
| POLR2J | INTS10 | 0.778081 | 3 | 0 | 3 |
| POLR2J | PLEKHH1 | 0.775856 | 3 | 0 | 3 |
| POLR2J | GPR153 | 0.772669 | 3 | 0 | 3 |
| POLR2J | SEMA3C | 0.768291 | 3 | 0 | 3 |
| POLR2J | PTCD1 | 0.765748 | 3 | 0 | 3 |
| POLR2J | FAM13A | 0.758141 | 3 | 0 | 3 |
| POLR2J | TCF7L2 | 0.757108 | 3 | 0 | 3 |
| POLR2J | MOSPD3 | 0.755042 | 3 | 0 | 3 |
| POLR2J | WDR81 | 0.752763 | 3 | 0 | 3 |
| POLR2J | KDM4A | 0.751222 | 3 | 0 | 3 |
| POLR2J | NGF | 0.750454 | 3 | 0 | 3 |
| POLR2J | PPP1R35 | 0.74761 | 8 | 0 | 8 |
| POLR2J | RAVER1 | 0.74051 | 5 | 0 | 5 |
| POLR2J | GNB1 | 0.739425 | 4 | 0 | 3 |
| POLR2J | LAMTOR4 | 0.736836 | 6 | 0 | 6 |
| POLR2J | FBXW8 | 0.734373 | 3 | 0 | 3 |
| POLR2J | PIK3R3 | 0.732775 | 3 | 0 | 3 |
| POLR2J | LRRC47 | 0.732737 | 3 | 0 | 3 |
For details and further investigation, click here
