| Full name: CASK interacting protein 1 | Alias Symbol: KIAA1306|ANKS5A | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 57524 | HGNC ID: HGNC:20879 | Ensembl Gene: ENSG00000167971 | OMIM ID: 612184 |
| Drug and gene relationship at DGIdb | |||
Expression of CASKIN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CASKIN1 | 57524 | 1552689_at | 0.3829 | 0.4277 | |
| GSE26886 | CASKIN1 | 57524 | 1552689_at | 0.4978 | 0.0332 | |
| GSE45670 | CASKIN1 | 57524 | 1552689_at | 0.4487 | 0.0016 | |
| GSE53622 | CASKIN1 | 57524 | 27720 | -0.1363 | 0.0027 | |
| GSE53624 | CASKIN1 | 57524 | 27720 | -0.1511 | 0.0065 | |
| GSE63941 | CASKIN1 | 57524 | 1552689_at | 0.0503 | 0.8153 | |
| GSE77861 | CASKIN1 | 57524 | 1552689_at | -0.0027 | 0.9796 | |
| GSE97050 | CASKIN1 | 57524 | A_33_P3349552 | -0.0258 | 0.9188 | |
| SRP159526 | CASKIN1 | 57524 | RNAseq | 2.3268 | 0.0000 | |
| TCGA | CASKIN1 | 57524 | RNAseq | 0.3381 | 0.2811 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CASKIN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CASKIN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CASKIN1 | 57524 | 5 | 5 | 20 | |
| GSE20123 | CASKIN1 | 57524 | 5 | 4 | 21 | |
| GSE43470 | CASKIN1 | 57524 | 4 | 7 | 32 | |
| GSE46452 | CASKIN1 | 57524 | 38 | 1 | 20 | |
| GSE47630 | CASKIN1 | 57524 | 13 | 6 | 21 | |
| GSE54993 | CASKIN1 | 57524 | 3 | 5 | 62 | |
| GSE54994 | CASKIN1 | 57524 | 5 | 9 | 39 | |
| GSE60625 | CASKIN1 | 57524 | 4 | 0 | 7 | |
| GSE74703 | CASKIN1 | 57524 | 4 | 5 | 27 | |
| GSE74704 | CASKIN1 | 57524 | 3 | 2 | 15 | |
| TCGA | CASKIN1 | 57524 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of CASKIN1:
Generating mutation plots.
Highly correlated genes for CASKIN1:
Showing top 20/97 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CASKIN1 | CHMP6 | 0.712823 | 3 | 0 | 3 |
| CASKIN1 | TNNI2 | 0.711804 | 3 | 0 | 3 |
| CASKIN1 | HMX1 | 0.683434 | 4 | 0 | 4 |
| CASKIN1 | DIABLO | 0.679569 | 5 | 0 | 4 |
| CASKIN1 | ADAMTS7 | 0.678677 | 4 | 0 | 3 |
| CASKIN1 | UFSP1 | 0.678157 | 3 | 0 | 3 |
| CASKIN1 | PROC | 0.668682 | 3 | 0 | 3 |
| CASKIN1 | MRGPRE | 0.66706 | 3 | 0 | 3 |
| CASKIN1 | MAP3K10 | 0.665081 | 3 | 0 | 3 |
| CASKIN1 | GPR152 | 0.663651 | 3 | 0 | 3 |
| CASKIN1 | SALL3 | 0.661912 | 3 | 0 | 3 |
| CASKIN1 | IL1F10 | 0.651652 | 5 | 0 | 4 |
| CASKIN1 | EDA | 0.6492 | 5 | 0 | 4 |
| CASKIN1 | HEATR4 | 0.647862 | 3 | 0 | 3 |
| CASKIN1 | GDF7 | 0.645285 | 3 | 0 | 3 |
| CASKIN1 | SRRM3 | 0.645167 | 4 | 0 | 3 |
| CASKIN1 | TNNI1 | 0.642447 | 4 | 0 | 3 |
| CASKIN1 | GH1 | 0.639703 | 4 | 0 | 3 |
| CASKIN1 | NOBOX | 0.638393 | 4 | 0 | 4 |
| CASKIN1 | CABP5 | 0.637099 | 3 | 0 | 3 |
For details and further investigation, click here
