| Full name: HEAT repeat containing 4 | Alias Symbol: MGC48595 | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 399671 | HGNC ID: HGNC:16761 | Ensembl Gene: ENSG00000187105 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HEATR4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HEATR4 | 399671 | 1560727_at | -0.0559 | 0.8848 | |
| GSE26886 | HEATR4 | 399671 | 1560727_at | 0.3774 | 0.0048 | |
| GSE45670 | HEATR4 | 399671 | 1560727_at | 0.0044 | 0.9760 | |
| GSE53622 | HEATR4 | 399671 | 2527 | 0.1563 | 0.2366 | |
| GSE53624 | HEATR4 | 399671 | 2527 | 0.1653 | 0.0449 | |
| GSE63941 | HEATR4 | 399671 | 1560727_at | 0.3574 | 0.1190 | |
| GSE77861 | HEATR4 | 399671 | 1560727_at | 0.0651 | 0.5777 | |
| GSE97050 | HEATR4 | 399671 | A_24_P696470 | -0.2921 | 0.2181 | |
| SRP133303 | HEATR4 | 399671 | RNAseq | 0.1395 | 0.4133 | |
| SRP159526 | HEATR4 | 399671 | RNAseq | 0.5016 | 0.4406 | |
| SRP193095 | HEATR4 | 399671 | RNAseq | 0.3470 | 0.0812 | |
| SRP219564 | HEATR4 | 399671 | RNAseq | 0.4442 | 0.2637 | |
| TCGA | HEATR4 | 399671 | RNAseq | 0.7260 | 0.0181 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HEATR4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HEATR4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HEATR4 | 399671 | 8 | 2 | 20 | |
| GSE20123 | HEATR4 | 399671 | 8 | 2 | 20 | |
| GSE43470 | HEATR4 | 399671 | 8 | 3 | 32 | |
| GSE46452 | HEATR4 | 399671 | 16 | 3 | 40 | |
| GSE47630 | HEATR4 | 399671 | 11 | 8 | 21 | |
| GSE54993 | HEATR4 | 399671 | 3 | 8 | 59 | |
| GSE54994 | HEATR4 | 399671 | 19 | 4 | 30 | |
| GSE60625 | HEATR4 | 399671 | 0 | 2 | 9 | |
| GSE74703 | HEATR4 | 399671 | 7 | 3 | 26 | |
| GSE74704 | HEATR4 | 399671 | 3 | 2 | 15 | |
| TCGA | HEATR4 | 399671 | 31 | 16 | 49 |
Total number of gains: 114; Total number of losses: 53; Total Number of normals: 321.
Somatic mutations of HEATR4:
Generating mutation plots.
Highly correlated genes for HEATR4:
Showing top 20/70 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HEATR4 | ARNTL | 0.687608 | 3 | 0 | 3 |
| HEATR4 | GLYATL1 | 0.686479 | 3 | 0 | 3 |
| HEATR4 | TMEM235 | 0.672991 | 3 | 0 | 3 |
| HEATR4 | WDR87 | 0.663726 | 3 | 0 | 3 |
| HEATR4 | GFRA2 | 0.655395 | 4 | 0 | 3 |
| HEATR4 | OPN4 | 0.655258 | 3 | 0 | 3 |
| HEATR4 | FOLH1 | 0.648121 | 3 | 0 | 3 |
| HEATR4 | CASKIN1 | 0.647862 | 3 | 0 | 3 |
| HEATR4 | SUPT3H | 0.646842 | 3 | 0 | 3 |
| HEATR4 | ATCAY | 0.645563 | 3 | 0 | 3 |
| HEATR4 | DYNC1LI1 | 0.644524 | 4 | 0 | 4 |
| HEATR4 | MUC2 | 0.640697 | 3 | 0 | 3 |
| HEATR4 | GRIK4 | 0.635742 | 4 | 0 | 4 |
| HEATR4 | STRC | 0.634584 | 3 | 0 | 3 |
| HEATR4 | TMEM105 | 0.63101 | 3 | 0 | 3 |
| HEATR4 | GOLGA7B | 0.630281 | 4 | 0 | 3 |
| HEATR4 | KAZALD1 | 0.628108 | 3 | 0 | 3 |
| HEATR4 | C19orf71 | 0.627928 | 3 | 0 | 3 |
| HEATR4 | NPPB | 0.625204 | 3 | 0 | 3 |
| HEATR4 | IGSF21 | 0.625058 | 3 | 0 | 3 |
For details and further investigation, click here
