| Full name: coiled-coil domain containing 105 | Alias Symbol: FLJ40365 | ||
| Type: protein-coding gene | Cytoband: 19p13.12 | ||
| Entrez ID: 126402 | HGNC ID: HGNC:26866 | Ensembl Gene: ENSG00000160994 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC105:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC105 | 126402 | 1553893_at | -0.1885 | 0.3024 | |
| GSE26886 | CCDC105 | 126402 | 1553893_at | -0.0679 | 0.6948 | |
| GSE45670 | CCDC105 | 126402 | 1553893_at | -0.1272 | 0.2065 | |
| GSE53622 | CCDC105 | 126402 | 67140 | 0.0194 | 0.9085 | |
| GSE53624 | CCDC105 | 126402 | 67140 | 0.1480 | 0.3025 | |
| GSE63941 | CCDC105 | 126402 | 1553893_at | 0.2392 | 0.1557 | |
| GSE77861 | CCDC105 | 126402 | 1553893_at | -0.2040 | 0.1086 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCDC105 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC105:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC105 | 126402 | 4 | 2 | 24 | |
| GSE20123 | CCDC105 | 126402 | 3 | 1 | 26 | |
| GSE43470 | CCDC105 | 126402 | 2 | 6 | 35 | |
| GSE46452 | CCDC105 | 126402 | 47 | 1 | 11 | |
| GSE47630 | CCDC105 | 126402 | 4 | 7 | 29 | |
| GSE54993 | CCDC105 | 126402 | 15 | 4 | 51 | |
| GSE54994 | CCDC105 | 126402 | 6 | 13 | 34 | |
| GSE60625 | CCDC105 | 126402 | 9 | 0 | 2 | |
| GSE74703 | CCDC105 | 126402 | 2 | 4 | 30 | |
| GSE74704 | CCDC105 | 126402 | 0 | 1 | 19 | |
| TCGA | CCDC105 | 126402 | 20 | 10 | 66 |
Total number of gains: 112; Total number of losses: 49; Total Number of normals: 327.
Somatic mutations of CCDC105:
Generating mutation plots.
Highly correlated genes for CCDC105:
Showing top 20/161 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC105 | STBD1 | 0.703717 | 3 | 0 | 3 |
| CCDC105 | SSUH2 | 0.678385 | 3 | 0 | 3 |
| CCDC105 | CYP3A43 | 0.674364 | 3 | 0 | 3 |
| CCDC105 | MAPT-AS1 | 0.667557 | 3 | 0 | 3 |
| CCDC105 | RPL29 | 0.662666 | 3 | 0 | 3 |
| CCDC105 | SMR3B | 0.649757 | 3 | 0 | 3 |
| CCDC105 | ANKS1B | 0.643295 | 3 | 0 | 3 |
| CCDC105 | SLC25A48 | 0.64325 | 4 | 0 | 4 |
| CCDC105 | SNAI1 | 0.641145 | 3 | 0 | 3 |
| CCDC105 | MUC8 | 0.640766 | 4 | 0 | 3 |
| CCDC105 | CEACAM3 | 0.640083 | 3 | 0 | 3 |
| CCDC105 | SGK2 | 0.635054 | 3 | 0 | 3 |
| CCDC105 | LKAAEAR1 | 0.631739 | 3 | 0 | 3 |
| CCDC105 | ALKBH3-AS1 | 0.627068 | 3 | 0 | 3 |
| CCDC105 | OPTC | 0.625644 | 4 | 0 | 3 |
| CCDC105 | TMEM114 | 0.62437 | 5 | 0 | 4 |
| CCDC105 | SOX10 | 0.62434 | 5 | 0 | 4 |
| CCDC105 | MTUS2 | 0.623691 | 4 | 0 | 3 |
| CCDC105 | AGTR2 | 0.623542 | 3 | 0 | 3 |
| CCDC105 | LDB3 | 0.622885 | 4 | 0 | 3 |
For details and further investigation, click here
