| Full name: microtubule associated scaffold protein 2 | Alias Symbol: TIP150|CAZIP|ICIS | ||
| Type: protein-coding gene | Cytoband: 13q12.3 | ||
| Entrez ID: 23281 | HGNC ID: HGNC:20595 | Ensembl Gene: ENSG00000132938 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MTUS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTUS2 | 23281 | 244676_s_at | -0.3849 | 0.2838 | |
| GSE20347 | MTUS2 | 23281 | 214961_at | -0.1588 | 0.0148 | |
| GSE23400 | MTUS2 | 23281 | 214961_at | -0.1283 | 0.0010 | |
| GSE26886 | MTUS2 | 23281 | 244676_s_at | -0.2704 | 0.0237 | |
| GSE29001 | MTUS2 | 23281 | 214961_at | -0.8475 | 0.0006 | |
| GSE38129 | MTUS2 | 23281 | 214961_at | -0.6981 | 0.0048 | |
| GSE53622 | MTUS2 | 23281 | 13505 | -1.3874 | 0.0000 | |
| GSE53624 | MTUS2 | 23281 | 13505 | -1.5350 | 0.0000 | |
| GSE63941 | MTUS2 | 23281 | 244676_s_at | 0.4071 | 0.0159 | |
| GSE77861 | MTUS2 | 23281 | 244676_s_at | -0.2161 | 0.0869 | |
| SRP133303 | MTUS2 | 23281 | RNAseq | -0.6436 | 0.3500 | |
| TCGA | MTUS2 | 23281 | RNAseq | -0.9660 | 0.0390 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MTUS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTUS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTUS2 | 23281 | 1 | 13 | 16 | |
| GSE20123 | MTUS2 | 23281 | 1 | 12 | 17 | |
| GSE43470 | MTUS2 | 23281 | 2 | 12 | 29 | |
| GSE46452 | MTUS2 | 23281 | 0 | 33 | 26 | |
| GSE47630 | MTUS2 | 23281 | 3 | 26 | 11 | |
| GSE54993 | MTUS2 | 23281 | 12 | 2 | 56 | |
| GSE54994 | MTUS2 | 23281 | 2 | 14 | 37 | |
| GSE60625 | MTUS2 | 23281 | 0 | 3 | 8 | |
| GSE74703 | MTUS2 | 23281 | 2 | 9 | 25 | |
| GSE74704 | MTUS2 | 23281 | 0 | 10 | 10 | |
| TCGA | MTUS2 | 23281 | 8 | 38 | 50 |
Total number of gains: 31; Total number of losses: 172; Total Number of normals: 285.
Somatic mutations of MTUS2:
Generating mutation plots.
Highly correlated genes for MTUS2:
Showing top 20/439 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTUS2 | SLC26A10 | 0.756187 | 4 | 0 | 4 |
| MTUS2 | NRXN3 | 0.735681 | 4 | 0 | 4 |
| MTUS2 | SORCS1 | 0.725657 | 3 | 0 | 3 |
| MTUS2 | TMEM114 | 0.72084 | 3 | 0 | 3 |
| MTUS2 | ADCYAP1R1 | 0.71567 | 3 | 0 | 3 |
| MTUS2 | MYOM1 | 0.714354 | 7 | 0 | 6 |
| MTUS2 | DOCK3 | 0.713085 | 5 | 0 | 5 |
| MTUS2 | MEF2C-AS1 | 0.710559 | 4 | 0 | 4 |
| MTUS2 | LARGE-AS1 | 0.709843 | 3 | 0 | 3 |
| MTUS2 | XKR4 | 0.708265 | 3 | 0 | 3 |
| MTUS2 | ITGA7 | 0.700788 | 6 | 0 | 6 |
| MTUS2 | MMP25 | 0.69829 | 3 | 0 | 3 |
| MTUS2 | NKX6-1 | 0.693978 | 7 | 0 | 7 |
| MTUS2 | CACNA1A | 0.6924 | 4 | 0 | 4 |
| MTUS2 | PDE3A | 0.689374 | 5 | 0 | 5 |
| MTUS2 | TACR2 | 0.68856 | 7 | 0 | 5 |
| MTUS2 | PLAC9 | 0.686035 | 4 | 0 | 4 |
| MTUS2 | HOXA4 | 0.685633 | 5 | 0 | 4 |
| MTUS2 | PYGM | 0.68495 | 8 | 0 | 6 |
| MTUS2 | SGCA | 0.683964 | 7 | 0 | 5 |
For details and further investigation, click here
