ENY2

 

Full name: ENY2 transcription and export complex 2 subunit Alias Symbol: DC6|FLJ20480|Sus1
Type: protein-coding gene Cytoband: 8q23.1
Entrez ID: 56943 HGNC ID: HGNC:24449 Ensembl Gene: ENSG00000120533 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of ENY2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ENY2 56943 218482_at 0.8007 0.1306
GSE20347 ENY2 56943 218482_at 1.2026 0.0000
GSE23400 ENY2 56943 218482_at 1.0175 0.0000
GSE26886 ENY2 56943 218482_at 0.8605 0.0001
GSE29001 ENY2 56943 218482_at 0.9073 0.0009
GSE38129 ENY2 56943 218482_at 1.0520 0.0000
GSE45670 ENY2 56943 218482_at 0.8045 0.0001
GSE53622 ENY2 56943 80631 0.4906 0.0000
GSE53624 ENY2 56943 80631 1.1530 0.0000
GSE63941 ENY2 56943 218482_at 0.4985 0.2118
GSE77861 ENY2 56943 218482_at 0.6466 0.0654
GSE97050 ENY2 56943 A_23_P82748 0.0786 0.7830
SRP007169 ENY2 56943 RNAseq 0.2778 0.4338
SRP008496 ENY2 56943 RNAseq 0.4464 0.0503
SRP064894 ENY2 56943 RNAseq 0.8124 0.0003
SRP133303 ENY2 56943 RNAseq 0.2815 0.0468
SRP159526 ENY2 56943 RNAseq 0.4327 0.0863
SRP193095 ENY2 56943 RNAseq 0.2069 0.0970
SRP219564 ENY2 56943 RNAseq 0.4960 0.1464
TCGA ENY2 56943 RNAseq 0.1704 0.0052

Upregulated datasets: 4; Downregulated datasets: 0.  

 

Survival by ENY2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ENY2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ENY2 56943 16 0 14
GSE20123 ENY2 56943 17 0 13
GSE43470 ENY2 56943 23 0 20
GSE46452 ENY2 56943 25 0 34
GSE47630 ENY2 56943 24 0 16
GSE54993 ENY2 56943 0 20 50
GSE54994 ENY2 56943 36 1 16
GSE60625 ENY2 56943 0 4 7
GSE74703 ENY2 56943 20 0 16
GSE74704 ENY2 56943 11 0 9
TCGA ENY2 56943 60 1 35

Total number of gains: 232; Total number of losses: 26; Total Number of normals: 230.  

 

Somatic mutations of ENY2:

 

Generating mutation plots.

 

Highly correlated genes for ENY2:

 

Showing top 20/1996 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ENY2CCDC1270.86328303
ENY2ATP6V1C10.79696113012
ENY2MTERF30.794411909
ENY2DPY19L40.79296912012
ENY2PET1170.788081303
ENY2SLC25A320.78740113012
ENY2POLR2K0.78143811010
ENY2STK30.77525711011
ENY2FADS10.771718303
ENY2PUF600.76387412012
ENY2SERPINH10.76012710010
ENY2SSB0.75856112012
ENY2MRPS280.75415310010
ENY2LAPTM4B0.753213012
ENY2PFDN20.74852712011
ENY2LPCAT10.74400711011
ENY2EXT10.7429410010
ENY2TATDN10.739816909
ENY2SLC39A30.734525404
ENY2CKS1B0.73406111010

For details and further investigation, click here