LPCAT1

 

Full name: lysophosphatidylcholine acyltransferase 1 Alias Symbol: FLJ12443|AGPAT9|AGPAT10
Type: protein-coding gene Cytoband: 5p15.33
Entrez ID: 79888 HGNC ID: HGNC:25718 Ensembl Gene: ENSG00000153395 OMIM ID: 610472
Drug and gene relationship at DGIdb

 

Expression of LPCAT1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LPCAT1 79888 201818_at 1.6488 0.0420
GSE20347 LPCAT1 79888 201818_at 1.9929 0.0000
GSE23400 LPCAT1 79888 201818_at 1.0446 0.0000
GSE26886 LPCAT1 79888 201818_at 2.9095 0.0000
GSE29001 LPCAT1 79888 201818_at 1.7308 0.0000
GSE38129 LPCAT1 79888 201818_at 1.6244 0.0000
GSE45670 LPCAT1 79888 201818_at 1.4592 0.0001
GSE53622 LPCAT1 79888 13931 1.7278 0.0000
GSE53624 LPCAT1 79888 13931 2.0754 0.0000
GSE63941 LPCAT1 79888 201818_at -0.5231 0.4151
GSE77861 LPCAT1 79888 201818_at 1.6719 0.0008
GSE97050 LPCAT1 79888 A_24_P406006 1.2659 0.0620
SRP007169 LPCAT1 79888 RNAseq 4.1114 0.0000
SRP008496 LPCAT1 79888 RNAseq 3.8049 0.0000
SRP064894 LPCAT1 79888 RNAseq 1.7656 0.0000
SRP133303 LPCAT1 79888 RNAseq 1.7773 0.0000
SRP159526 LPCAT1 79888 RNAseq 1.4327 0.0000
SRP193095 LPCAT1 79888 RNAseq 2.0518 0.0000
SRP219564 LPCAT1 79888 RNAseq 1.5828 0.0123
TCGA LPCAT1 79888 RNAseq 0.3056 0.0003

Upregulated datasets: 17; Downregulated datasets: 0.  

 

Survival by LPCAT1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of LPCAT1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LPCAT1 79888 13 1 16
GSE20123 LPCAT1 79888 13 1 16
GSE43470 LPCAT1 79888 17 1 25
GSE46452 LPCAT1 79888 6 22 31
GSE47630 LPCAT1 79888 7 11 22
GSE54993 LPCAT1 79888 5 5 60
GSE54994 LPCAT1 79888 29 1 23
GSE60625 LPCAT1 79888 0 0 11
GSE74703 LPCAT1 79888 14 0 22
GSE74704 LPCAT1 79888 11 0 9
TCGA LPCAT1 79888 59 3 34

Total number of gains: 174; Total number of losses: 45; Total Number of normals: 269.  

 

Somatic mutations of LPCAT1:

 

Generating mutation plots.

 

Highly correlated genes for LPCAT1:

 

Showing top 20/2336 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LPCAT1FMNL20.867226707
LPCAT1FADS10.843774303
LPCAT1SERPINH10.83879910010
LPCAT1FNDC3B0.83855911011
LPCAT1PLOD10.82248112012
LPCAT1MSN0.81977711011
LPCAT1WDR540.817129707
LPCAT1XPR10.814452707
LPCAT1GNG100.811749303
LPCAT1CTHRC10.808197706
LPCAT1LRRC8C0.802025303
LPCAT1COLGALT10.79987810010
LPCAT1LAPTM4B0.79976811011
LPCAT1LRP120.79876411011
LPCAT1TRAM20.79867711011
LPCAT1CCDC1270.7978303
LPCAT1TMEM184B0.79344111011
LPCAT1SLC39A140.78746811011
LPCAT1RAB340.786185303
LPCAT1SDHAF20.78594303

For details and further investigation, click here