| Full name: quiescin sulfhydryl oxidase 2 | Alias Symbol: SOXN|DKFZp762A2013 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 169714 | HGNC ID: HGNC:30249 | Ensembl Gene: ENSG00000165661 | OMIM ID: 612860 |
| Drug and gene relationship at DGIdb | |||
Expression of QSOX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | QSOX2 | 169714 | 227146_at | 0.4918 | 0.0985 | |
| GSE26886 | QSOX2 | 169714 | 227146_at | 0.6349 | 0.0105 | |
| GSE45670 | QSOX2 | 169714 | 227146_at | 0.7189 | 0.0001 | |
| GSE53622 | QSOX2 | 169714 | 82784 | 0.6594 | 0.0000 | |
| GSE53624 | QSOX2 | 169714 | 82784 | 0.8741 | 0.0000 | |
| GSE63941 | QSOX2 | 169714 | 227146_at | -0.0246 | 0.9624 | |
| GSE77861 | QSOX2 | 169714 | 227146_at | 0.4454 | 0.0020 | |
| GSE97050 | QSOX2 | 169714 | A_32_P206401 | 0.1996 | 0.3408 | |
| SRP007169 | QSOX2 | 169714 | RNAseq | 2.5266 | 0.0000 | |
| SRP008496 | QSOX2 | 169714 | RNAseq | 2.6907 | 0.0000 | |
| SRP064894 | QSOX2 | 169714 | RNAseq | 1.1499 | 0.0000 | |
| SRP133303 | QSOX2 | 169714 | RNAseq | 1.0093 | 0.0000 | |
| SRP159526 | QSOX2 | 169714 | RNAseq | 1.2649 | 0.0000 | |
| SRP193095 | QSOX2 | 169714 | RNAseq | 1.2766 | 0.0000 | |
| SRP219564 | QSOX2 | 169714 | RNAseq | 0.9965 | 0.0044 | |
| TCGA | QSOX2 | 169714 | RNAseq | 0.2319 | 0.0010 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by QSOX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of QSOX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | QSOX2 | 169714 | 4 | 7 | 19 | |
| GSE20123 | QSOX2 | 169714 | 4 | 7 | 19 | |
| GSE43470 | QSOX2 | 169714 | 3 | 7 | 33 | |
| GSE46452 | QSOX2 | 169714 | 6 | 13 | 40 | |
| GSE47630 | QSOX2 | 169714 | 6 | 15 | 19 | |
| GSE54993 | QSOX2 | 169714 | 3 | 3 | 64 | |
| GSE54994 | QSOX2 | 169714 | 12 | 8 | 33 | |
| GSE60625 | QSOX2 | 169714 | 0 | 0 | 11 | |
| GSE74703 | QSOX2 | 169714 | 3 | 5 | 28 | |
| GSE74704 | QSOX2 | 169714 | 2 | 5 | 13 | |
| TCGA | QSOX2 | 169714 | 29 | 24 | 43 |
Total number of gains: 72; Total number of losses: 94; Total Number of normals: 322.
Somatic mutations of QSOX2:
Generating mutation plots.
Highly correlated genes for QSOX2:
Showing top 20/1549 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| QSOX2 | SLC39A3 | 0.838195 | 3 | 0 | 3 |
| QSOX2 | DHRSX | 0.834427 | 3 | 0 | 3 |
| QSOX2 | CCDC127 | 0.805334 | 3 | 0 | 3 |
| QSOX2 | RNF166 | 0.802153 | 3 | 0 | 3 |
| QSOX2 | GPAA1 | 0.797098 | 3 | 0 | 3 |
| QSOX2 | ATM | 0.782099 | 3 | 0 | 3 |
| QSOX2 | UCP2 | 0.780633 | 3 | 0 | 3 |
| QSOX2 | FZD6 | 0.776351 | 4 | 0 | 4 |
| QSOX2 | MAP2K7 | 0.774486 | 3 | 0 | 3 |
| QSOX2 | CLCN7 | 0.771804 | 4 | 0 | 4 |
| QSOX2 | PPTC7 | 0.770722 | 3 | 0 | 3 |
| QSOX2 | EMG1 | 0.769693 | 3 | 0 | 3 |
| QSOX2 | CPT1A | 0.766121 | 3 | 0 | 3 |
| QSOX2 | CDK18 | 0.752325 | 3 | 0 | 3 |
| QSOX2 | TFDP2 | 0.749913 | 3 | 0 | 3 |
| QSOX2 | CACNA1B | 0.749284 | 3 | 0 | 3 |
| QSOX2 | ZDHHC17 | 0.74646 | 3 | 0 | 3 |
| QSOX2 | KNOP1 | 0.745429 | 4 | 0 | 4 |
| QSOX2 | CCT5 | 0.743206 | 5 | 0 | 5 |
| QSOX2 | MTBP | 0.742493 | 5 | 0 | 5 |
For details and further investigation, click here
