| Full name: nuclear receptor subfamily 2 group F member 2 | Alias Symbol: COUP-TFII|COUPTFB|SVP40|NF-E3|COUPTF2 | ||
| Type: protein-coding gene | Cytoband: 15q26.2 | ||
| Entrez ID: 7026 | HGNC ID: HGNC:7976 | Ensembl Gene: ENSG00000185551 | OMIM ID: 107773 |
| Drug and gene relationship at DGIdb | |||
Expression of NR2F2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NR2F2 | 7026 | 209120_at | -0.5810 | 0.5076 | |
| GSE20347 | NR2F2 | 7026 | 209121_x_at | 0.2539 | 0.2816 | |
| GSE23400 | NR2F2 | 7026 | 209121_x_at | -0.2997 | 0.0286 | |
| GSE26886 | NR2F2 | 7026 | 209120_at | 1.1243 | 0.0218 | |
| GSE29001 | NR2F2 | 7026 | 209120_at | 0.1172 | 0.8353 | |
| GSE38129 | NR2F2 | 7026 | 209121_x_at | -0.4904 | 0.1770 | |
| GSE45670 | NR2F2 | 7026 | 209121_x_at | -1.2490 | 0.0003 | |
| GSE53622 | NR2F2 | 7026 | 85502 | -0.6488 | 0.0000 | |
| GSE53624 | NR2F2 | 7026 | 85502 | -0.4371 | 0.0002 | |
| GSE63941 | NR2F2 | 7026 | 209121_x_at | -1.7355 | 0.1457 | |
| GSE77861 | NR2F2 | 7026 | 209121_x_at | 0.6349 | 0.0318 | |
| GSE97050 | NR2F2 | 7026 | A_23_P88589 | -0.8733 | 0.1339 | |
| SRP007169 | NR2F2 | 7026 | RNAseq | 2.0159 | 0.0001 | |
| SRP008496 | NR2F2 | 7026 | RNAseq | 2.1108 | 0.0000 | |
| SRP064894 | NR2F2 | 7026 | RNAseq | 0.4880 | 0.1800 | |
| SRP133303 | NR2F2 | 7026 | RNAseq | -0.5126 | 0.1119 | |
| SRP159526 | NR2F2 | 7026 | RNAseq | 0.7166 | 0.0769 | |
| SRP193095 | NR2F2 | 7026 | RNAseq | 0.2294 | 0.4844 | |
| SRP219564 | NR2F2 | 7026 | RNAseq | 0.1157 | 0.8732 | |
| TCGA | NR2F2 | 7026 | RNAseq | -0.6851 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by NR2F2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NR2F2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NR2F2 | 7026 | 7 | 2 | 21 | |
| GSE20123 | NR2F2 | 7026 | 7 | 2 | 21 | |
| GSE43470 | NR2F2 | 7026 | 5 | 5 | 33 | |
| GSE46452 | NR2F2 | 7026 | 3 | 7 | 49 | |
| GSE47630 | NR2F2 | 7026 | 9 | 10 | 21 | |
| GSE54993 | NR2F2 | 7026 | 4 | 6 | 60 | |
| GSE54994 | NR2F2 | 7026 | 9 | 7 | 37 | |
| GSE60625 | NR2F2 | 7026 | 4 | 0 | 7 | |
| GSE74703 | NR2F2 | 7026 | 4 | 4 | 28 | |
| GSE74704 | NR2F2 | 7026 | 4 | 2 | 14 | |
| TCGA | NR2F2 | 7026 | 18 | 12 | 66 |
Total number of gains: 74; Total number of losses: 57; Total Number of normals: 357.
Somatic mutations of NR2F2:
Generating mutation plots.
Highly correlated genes for NR2F2:
Showing top 20/1155 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NR2F2 | CAMK2G | 0.774545 | 4 | 0 | 4 |
| NR2F2 | EMCN | 0.768237 | 5 | 0 | 5 |
| NR2F2 | MEOX2 | 0.767141 | 8 | 0 | 7 |
| NR2F2 | CAMKK2 | 0.756118 | 3 | 0 | 3 |
| NR2F2 | EIF5A2 | 0.747573 | 3 | 0 | 3 |
| NR2F2 | SNX25 | 0.74728 | 3 | 0 | 3 |
| NR2F2 | PDLIM3 | 0.744438 | 11 | 0 | 11 |
| NR2F2 | SOBP | 0.742089 | 10 | 0 | 10 |
| NR2F2 | TMED8 | 0.740671 | 3 | 0 | 3 |
| NR2F2 | SORCS1 | 0.737991 | 4 | 0 | 4 |
| NR2F2 | TNFSF12 | 0.735357 | 4 | 0 | 3 |
| NR2F2 | TMTC4 | 0.733893 | 3 | 0 | 3 |
| NR2F2 | ZNF496 | 0.733561 | 3 | 0 | 3 |
| NR2F2 | PDE1A | 0.732662 | 10 | 0 | 9 |
| NR2F2 | ANXA6 | 0.731522 | 11 | 0 | 10 |
| NR2F2 | ITGB1BP2 | 0.730794 | 3 | 0 | 3 |
| NR2F2 | TCEAL5 | 0.729672 | 3 | 0 | 3 |
| NR2F2 | ORAI3 | 0.72819 | 4 | 0 | 3 |
| NR2F2 | LINC01279 | 0.72792 | 4 | 0 | 4 |
| NR2F2 | ZNF423 | 0.727821 | 9 | 0 | 7 |
For details and further investigation, click here
