| Full name: CD2 cytoplasmic tail binding protein 2 | Alias Symbol: LIN1|Snu40|PPP1R59|U5-52K | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 10421 | HGNC ID: HGNC:1656 | Ensembl Gene: ENSG00000169217 | OMIM ID: 604470 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of CD2BP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD2BP2 | 10421 | 202257_s_at | -0.0914 | 0.7753 | |
| GSE20347 | CD2BP2 | 10421 | 202257_s_at | -0.3157 | 0.0002 | |
| GSE23400 | CD2BP2 | 10421 | 202257_s_at | -0.1362 | 0.0088 | |
| GSE26886 | CD2BP2 | 10421 | 202257_s_at | -0.1305 | 0.4032 | |
| GSE29001 | CD2BP2 | 10421 | 202256_at | 0.6446 | 0.0227 | |
| GSE38129 | CD2BP2 | 10421 | 202257_s_at | -0.1578 | 0.0385 | |
| GSE45670 | CD2BP2 | 10421 | 202257_s_at | 0.1400 | 0.2147 | |
| GSE53622 | CD2BP2 | 10421 | 41136 | 0.5352 | 0.0000 | |
| GSE53624 | CD2BP2 | 10421 | 41136 | 0.9187 | 0.0000 | |
| GSE63941 | CD2BP2 | 10421 | 202257_s_at | -0.1777 | 0.6777 | |
| GSE77861 | CD2BP2 | 10421 | 202257_s_at | 0.0119 | 0.9691 | |
| GSE97050 | CD2BP2 | 10421 | A_24_P236522 | -0.2648 | 0.3967 | |
| SRP007169 | CD2BP2 | 10421 | RNAseq | 1.1575 | 0.0126 | |
| SRP008496 | CD2BP2 | 10421 | RNAseq | 1.0754 | 0.0006 | |
| SRP064894 | CD2BP2 | 10421 | RNAseq | 0.2584 | 0.2384 | |
| SRP133303 | CD2BP2 | 10421 | RNAseq | 0.5295 | 0.0001 | |
| SRP159526 | CD2BP2 | 10421 | RNAseq | 0.2372 | 0.2383 | |
| SRP193095 | CD2BP2 | 10421 | RNAseq | 0.2402 | 0.0075 | |
| SRP219564 | CD2BP2 | 10421 | RNAseq | -0.0245 | 0.9257 | |
| TCGA | CD2BP2 | 10421 | RNAseq | 0.0503 | 0.3123 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CD2BP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD2BP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD2BP2 | 10421 | 5 | 5 | 20 | |
| GSE20123 | CD2BP2 | 10421 | 5 | 4 | 21 | |
| GSE43470 | CD2BP2 | 10421 | 3 | 3 | 37 | |
| GSE46452 | CD2BP2 | 10421 | 38 | 1 | 20 | |
| GSE47630 | CD2BP2 | 10421 | 11 | 7 | 22 | |
| GSE54993 | CD2BP2 | 10421 | 2 | 5 | 63 | |
| GSE54994 | CD2BP2 | 10421 | 5 | 9 | 39 | |
| GSE60625 | CD2BP2 | 10421 | 4 | 0 | 7 | |
| GSE74703 | CD2BP2 | 10421 | 3 | 2 | 31 | |
| GSE74704 | CD2BP2 | 10421 | 3 | 2 | 15 | |
| TCGA | CD2BP2 | 10421 | 20 | 10 | 66 |
Total number of gains: 99; Total number of losses: 48; Total Number of normals: 341.
Somatic mutations of CD2BP2:
Generating mutation plots.
Highly correlated genes for CD2BP2:
Showing top 20/264 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD2BP2 | SWAP70 | 0.823039 | 3 | 0 | 3 |
| CD2BP2 | LRRC28 | 0.773078 | 3 | 0 | 3 |
| CD2BP2 | USP42 | 0.75056 | 3 | 0 | 3 |
| CD2BP2 | ASCC1 | 0.73865 | 3 | 0 | 3 |
| CD2BP2 | MRPL46 | 0.731684 | 3 | 0 | 3 |
| CD2BP2 | SSNA1 | 0.730996 | 3 | 0 | 3 |
| CD2BP2 | WDR20 | 0.730817 | 3 | 0 | 3 |
| CD2BP2 | CCDC65 | 0.729713 | 3 | 0 | 3 |
| CD2BP2 | MRPL10 | 0.727548 | 3 | 0 | 3 |
| CD2BP2 | DDX54 | 0.719381 | 3 | 0 | 3 |
| CD2BP2 | STK19 | 0.713866 | 3 | 0 | 3 |
| CD2BP2 | C20orf27 | 0.712574 | 4 | 0 | 4 |
| CD2BP2 | AGK | 0.710463 | 3 | 0 | 3 |
| CD2BP2 | SCNM1 | 0.708709 | 3 | 0 | 3 |
| CD2BP2 | MIPEP | 0.707278 | 4 | 0 | 3 |
| CD2BP2 | TAF6 | 0.704573 | 4 | 0 | 4 |
| CD2BP2 | MTFMT | 0.704313 | 3 | 0 | 3 |
| CD2BP2 | PHLPP1 | 0.702137 | 3 | 0 | 3 |
| CD2BP2 | RNF181 | 0.700689 | 5 | 0 | 5 |
| CD2BP2 | PLD6 | 0.69655 | 3 | 0 | 3 |
For details and further investigation, click here
