| Full name: coiled-coil domain containing 88C | Alias Symbol: DAPLE|HkRP2|SCA40 | ||
| Type: protein-coding gene | Cytoband: 14q32.11-q32.12 | ||
| Entrez ID: 440193 | HGNC ID: HGNC:19967 | Ensembl Gene: ENSG00000015133 | OMIM ID: 611204 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CCDC88C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC88C | 440193 | 227228_s_at | 0.7069 | 0.2197 | |
| GSE20347 | CCDC88C | 440193 | 215343_at | 0.3225 | 0.0223 | |
| GSE23400 | CCDC88C | 440193 | 215343_at | 0.2327 | 0.0000 | |
| GSE26886 | CCDC88C | 440193 | 227228_s_at | -0.9194 | 0.0002 | |
| GSE29001 | CCDC88C | 440193 | 215343_at | 0.5746 | 0.0290 | |
| GSE38129 | CCDC88C | 440193 | 215343_at | 0.4855 | 0.0020 | |
| GSE45670 | CCDC88C | 440193 | 227228_s_at | 0.4840 | 0.0215 | |
| GSE53622 | CCDC88C | 440193 | 52365 | -0.5313 | 0.0000 | |
| GSE53624 | CCDC88C | 440193 | 52365 | -0.4793 | 0.0000 | |
| GSE63941 | CCDC88C | 440193 | 227228_s_at | 2.1377 | 0.0030 | |
| GSE77861 | CCDC88C | 440193 | 227228_s_at | 0.2287 | 0.5528 | |
| GSE97050 | CCDC88C | 440193 | A_24_P136094 | -0.6415 | 0.0976 | |
| SRP007169 | CCDC88C | 440193 | RNAseq | 1.0393 | 0.0137 | |
| SRP008496 | CCDC88C | 440193 | RNAseq | 0.6871 | 0.0465 | |
| SRP064894 | CCDC88C | 440193 | RNAseq | 0.2373 | 0.3771 | |
| SRP133303 | CCDC88C | 440193 | RNAseq | -0.1328 | 0.5421 | |
| SRP159526 | CCDC88C | 440193 | RNAseq | -0.0393 | 0.8684 | |
| SRP193095 | CCDC88C | 440193 | RNAseq | 0.0924 | 0.5864 | |
| SRP219564 | CCDC88C | 440193 | RNAseq | 0.4503 | 0.5185 | |
| TCGA | CCDC88C | 440193 | RNAseq | 0.0556 | 0.4781 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CCDC88C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC88C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC88C | 440193 | 9 | 5 | 16 | |
| GSE20123 | CCDC88C | 440193 | 9 | 5 | 16 | |
| GSE43470 | CCDC88C | 440193 | 7 | 3 | 33 | |
| GSE46452 | CCDC88C | 440193 | 16 | 3 | 40 | |
| GSE47630 | CCDC88C | 440193 | 11 | 8 | 21 | |
| GSE54993 | CCDC88C | 440193 | 3 | 8 | 59 | |
| GSE54994 | CCDC88C | 440193 | 19 | 4 | 30 | |
| GSE60625 | CCDC88C | 440193 | 0 | 2 | 9 | |
| GSE74703 | CCDC88C | 440193 | 6 | 3 | 27 | |
| GSE74704 | CCDC88C | 440193 | 4 | 4 | 12 | |
| TCGA | CCDC88C | 440193 | 30 | 21 | 45 |
Total number of gains: 114; Total number of losses: 66; Total Number of normals: 308.
Somatic mutations of CCDC88C:
Generating mutation plots.
Highly correlated genes for CCDC88C:
Showing top 20/84 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC88C | TMEM53 | 0.794314 | 3 | 0 | 3 |
| CCDC88C | TMEM200C | 0.730243 | 4 | 0 | 4 |
| CCDC88C | ERICH4 | 0.68916 | 3 | 0 | 3 |
| CCDC88C | TRAF3IP2-AS1 | 0.684458 | 3 | 0 | 3 |
| CCDC88C | PFN1 | 0.67737 | 3 | 0 | 3 |
| CCDC88C | TNR | 0.668257 | 3 | 0 | 3 |
| CCDC88C | UQCRC1 | 0.663941 | 3 | 0 | 3 |
| CCDC88C | PCBD1 | 0.659337 | 3 | 0 | 3 |
| CCDC88C | POLR1D | 0.652075 | 4 | 0 | 3 |
| CCDC88C | SZT2 | 0.651098 | 3 | 0 | 3 |
| CCDC88C | CCDC85C | 0.650326 | 6 | 0 | 4 |
| CCDC88C | SFTPA2 | 0.641004 | 3 | 0 | 3 |
| CCDC88C | MOG | 0.636731 | 4 | 0 | 3 |
| CCDC88C | FEM1A | 0.634495 | 4 | 0 | 4 |
| CCDC88C | KLRG2 | 0.632167 | 4 | 0 | 3 |
| CCDC88C | DUSP8 | 0.630298 | 3 | 0 | 3 |
| CCDC88C | SELPLG | 0.630147 | 3 | 0 | 3 |
| CCDC88C | ADAD2 | 0.62343 | 4 | 0 | 3 |
| CCDC88C | ACTRT1 | 0.619123 | 3 | 0 | 3 |
| CCDC88C | PTPRF | 0.61781 | 5 | 0 | 4 |
For details and further investigation, click here
