| Full name: RNA polymerase I and III subunit D | Alias Symbol: RPAC2|RPA16|RPO1-3|RPA9|MGC9850 | ||
| Type: protein-coding gene | Cytoband: 13q12.2 | ||
| Entrez ID: 51082 | HGNC ID: HGNC:20422 | Ensembl Gene: ENSG00000186184 | OMIM ID: 613715 |
| Drug and gene relationship at DGIdb | |||
Expression of POLR1D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POLR1D | 51082 | 218258_at | -0.5316 | 0.1171 | |
| GSE20347 | POLR1D | 51082 | 218258_at | -0.4970 | 0.0060 | |
| GSE23400 | POLR1D | 51082 | 218258_at | -0.3771 | 0.0004 | |
| GSE26886 | POLR1D | 51082 | 224874_at | -1.2156 | 0.0000 | |
| GSE29001 | POLR1D | 51082 | 218258_at | -0.7928 | 0.0358 | |
| GSE38129 | POLR1D | 51082 | 218258_at | -0.2649 | 0.0856 | |
| GSE45670 | POLR1D | 51082 | 218258_at | -0.2746 | 0.1166 | |
| GSE53622 | POLR1D | 51082 | 30918 | -0.6501 | 0.0000 | |
| GSE53624 | POLR1D | 51082 | 38299 | -0.3862 | 0.0000 | |
| GSE63941 | POLR1D | 51082 | 218258_at | 1.1046 | 0.0559 | |
| GSE77861 | POLR1D | 51082 | 218258_at | -0.2330 | 0.4450 | |
| GSE97050 | POLR1D | 51082 | A_23_P409541 | -1.0375 | 0.0844 | |
| SRP007169 | POLR1D | 51082 | RNAseq | -1.8759 | 0.0000 | |
| SRP008496 | POLR1D | 51082 | RNAseq | -1.6187 | 0.0000 | |
| SRP064894 | POLR1D | 51082 | RNAseq | -0.4917 | 0.0515 | |
| SRP133303 | POLR1D | 51082 | RNAseq | -0.5130 | 0.0121 | |
| SRP159526 | POLR1D | 51082 | RNAseq | -0.7975 | 0.0073 | |
| SRP193095 | POLR1D | 51082 | RNAseq | -0.8854 | 0.0000 | |
| SRP219564 | POLR1D | 51082 | RNAseq | -1.0026 | 0.0037 | |
| TCGA | POLR1D | 51082 | RNAseq | -0.0152 | 0.7425 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by POLR1D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POLR1D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POLR1D | 51082 | 1 | 13 | 16 | |
| GSE20123 | POLR1D | 51082 | 1 | 12 | 17 | |
| GSE43470 | POLR1D | 51082 | 2 | 12 | 29 | |
| GSE46452 | POLR1D | 51082 | 0 | 33 | 26 | |
| GSE47630 | POLR1D | 51082 | 3 | 26 | 11 | |
| GSE54993 | POLR1D | 51082 | 11 | 2 | 57 | |
| GSE54994 | POLR1D | 51082 | 1 | 13 | 39 | |
| GSE60625 | POLR1D | 51082 | 0 | 3 | 8 | |
| GSE74703 | POLR1D | 51082 | 2 | 9 | 25 | |
| GSE74704 | POLR1D | 51082 | 0 | 10 | 10 | |
| TCGA | POLR1D | 51082 | 6 | 41 | 49 |
Total number of gains: 27; Total number of losses: 174; Total Number of normals: 287.
Somatic mutations of POLR1D:
Generating mutation plots.
Highly correlated genes for POLR1D:
Showing top 20/444 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POLR1D | GADD45G | 0.696011 | 3 | 0 | 3 |
| POLR1D | CNKSR3 | 0.679445 | 5 | 0 | 4 |
| POLR1D | ANKS1B | 0.679175 | 3 | 0 | 3 |
| POLR1D | ZNF585A | 0.67226 | 3 | 0 | 3 |
| POLR1D | PPP2R2A | 0.654163 | 6 | 0 | 6 |
| POLR1D | CCDC88C | 0.652075 | 4 | 0 | 3 |
| POLR1D | DOCK3 | 0.635582 | 4 | 0 | 4 |
| POLR1D | GPS2 | 0.635249 | 3 | 0 | 3 |
| POLR1D | RAC1 | 0.632992 | 4 | 0 | 4 |
| POLR1D | HUWE1 | 0.631944 | 5 | 0 | 4 |
| POLR1D | AHNAK | 0.630235 | 7 | 0 | 6 |
| POLR1D | GOLGA8N | 0.629443 | 3 | 0 | 3 |
| POLR1D | CST3 | 0.627596 | 3 | 0 | 3 |
| POLR1D | ADAMTSL4 | 0.616666 | 3 | 0 | 3 |
| POLR1D | UQCRC2 | 0.615063 | 6 | 0 | 5 |
| POLR1D | PHYHD1 | 0.612179 | 4 | 0 | 4 |
| POLR1D | SAP18 | 0.608701 | 11 | 0 | 8 |
| POLR1D | STX17 | 0.605445 | 9 | 0 | 7 |
| POLR1D | UCHL3 | 0.605369 | 8 | 0 | 6 |
| POLR1D | MAP2K4 | 0.605363 | 7 | 0 | 6 |
For details and further investigation, click here
