CCDC96

 

Full name: coiled-coil domain containing 96 Alias Symbol: FLJ90575
Type: protein-coding gene Cytoband: 4p16.1
Entrez ID: 257236 HGNC ID: HGNC:26900 Ensembl Gene: ENSG00000173013 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of CCDC96:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CCDC96 257236 238682_at 0.0435 0.9286
GSE26886 CCDC96 257236 238682_at -0.6253 0.0047
GSE45670 CCDC96 257236 238682_at -0.0462 0.8275
GSE53622 CCDC96 257236 52872 -0.3814 0.0000
GSE53624 CCDC96 257236 52872 -0.5029 0.0000
GSE63941 CCDC96 257236 238682_at -0.8649 0.0048
GSE77861 CCDC96 257236 238682_at -0.1134 0.3902
GSE97050 CCDC96 257236 A_32_P69930 -0.0426 0.8634
SRP064894 CCDC96 257236 RNAseq -0.3438 0.2645
SRP133303 CCDC96 257236 RNAseq -0.3636 0.1890
SRP159526 CCDC96 257236 RNAseq -0.7747 0.0635
SRP219564 CCDC96 257236 RNAseq -0.8629 0.0368
TCGA CCDC96 257236 RNAseq -0.3645 0.0075

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by CCDC96 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CCDC96:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CCDC96 257236 0 18 12
GSE20123 CCDC96 257236 0 18 12
GSE43470 CCDC96 257236 0 17 26
GSE46452 CCDC96 257236 1 36 22
GSE47630 CCDC96 257236 1 19 20
GSE54993 CCDC96 257236 10 0 60
GSE54994 CCDC96 257236 3 12 38
GSE60625 CCDC96 257236 0 0 11
GSE74703 CCDC96 257236 0 13 23
GSE74704 CCDC96 257236 0 10 10
TCGA CCDC96 257236 7 48 41

Total number of gains: 22; Total number of losses: 191; Total Number of normals: 275.  


 

Somatic mutations of CCDC96:

 

Generating mutation plots.

 

Highly correlated genes for CCDC96:

 

Showing top 20/77 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CCDC96LARP4B0.746456303
CCDC96CDK150.701253303
CCDC96ARHGAP230.683043303
CCDC96NUDT16L10.680437404
CCDC96SUDS30.673782303
CCDC96CTAGE10.673493303
CCDC96ZNF6210.662565303
CCDC96NOL40.659562303
CCDC96PABPC10.657732303
CCDC96ZNF6820.642755504
CCDC96TBKBP10.625504303
CCDC96PCYT20.612897404
CCDC96LINC011110.610759303
CCDC96CCNB30.605822303
CCDC96NDUFB2-AS10.603828303
CCDC96PGAP30.600223404
CCDC96SHROOM20.596858404
CCDC96NCKAP50.592411503
CCDC96CNDP20.58904403
CCDC96SNIP10.586832303

For details and further investigation, click here