| Full name: Rho GTPase activating protein 23 | Alias Symbol: KIAA1501 | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 57636 | HGNC ID: HGNC:29293 | Ensembl Gene: ENSG00000275832 | OMIM ID: 610590 |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGAP23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGAP23 | 57636 | 226638_at | 0.4808 | 0.4022 | |
| GSE26886 | ARHGAP23 | 57636 | 226638_at | 0.0190 | 0.9533 | |
| GSE45670 | ARHGAP23 | 57636 | 226638_at | 0.4516 | 0.0337 | |
| GSE63941 | ARHGAP23 | 57636 | 226638_at | 0.4512 | 0.5905 | |
| GSE77861 | ARHGAP23 | 57636 | 226638_at | 0.0189 | 0.9550 | |
| GSE97050 | ARHGAP23 | 57636 | A_33_P3358914 | 0.5688 | 0.1986 | |
| SRP007169 | ARHGAP23 | 57636 | RNAseq | 0.2588 | 0.5720 | |
| SRP008496 | ARHGAP23 | 57636 | RNAseq | -0.2407 | 0.4308 | |
| SRP064894 | ARHGAP23 | 57636 | RNAseq | -0.0989 | 0.6853 | |
| SRP133303 | ARHGAP23 | 57636 | RNAseq | 0.0018 | 0.9928 | |
| SRP159526 | ARHGAP23 | 57636 | RNAseq | -0.3419 | 0.4995 | |
| SRP193095 | ARHGAP23 | 57636 | RNAseq | 0.2421 | 0.3942 | |
| SRP219564 | ARHGAP23 | 57636 | RNAseq | -0.7985 | 0.0489 | |
| TCGA | ARHGAP23 | 57636 | RNAseq | 0.3392 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARHGAP23 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ARHGAP23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGAP23 | 57636 | 6 | 1 | 23 | |
| GSE20123 | ARHGAP23 | 57636 | 6 | 1 | 23 | |
| GSE43470 | ARHGAP23 | 57636 | 1 | 1 | 41 | |
| GSE46452 | ARHGAP23 | 57636 | 34 | 0 | 25 | |
| GSE47630 | ARHGAP23 | 57636 | 8 | 1 | 31 | |
| GSE54993 | ARHGAP23 | 57636 | 3 | 3 | 64 | |
| GSE54994 | ARHGAP23 | 57636 | 8 | 5 | 40 | |
| GSE60625 | ARHGAP23 | 57636 | 4 | 0 | 7 | |
| GSE74703 | ARHGAP23 | 57636 | 1 | 0 | 35 | |
| GSE74704 | ARHGAP23 | 57636 | 3 | 1 | 16 | |
| TCGA | ARHGAP23 | 57636 | 19 | 9 | 68 |
Total number of gains: 93; Total number of losses: 22; Total Number of normals: 373.
Somatic mutations of ARHGAP23:
Generating mutation plots.
Highly correlated genes for ARHGAP23:
Showing top 20/46 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGAP23 | TARBP2 | 0.743825 | 3 | 0 | 3 |
| ARHGAP23 | ZNF687 | 0.720221 | 3 | 0 | 3 |
| ARHGAP23 | FAM189B | 0.719285 | 3 | 0 | 3 |
| ARHGAP23 | RALY | 0.688669 | 3 | 0 | 3 |
| ARHGAP23 | CCDC96 | 0.683043 | 3 | 0 | 3 |
| ARHGAP23 | LIPE | 0.675681 | 3 | 0 | 3 |
| ARHGAP23 | POC1A | 0.6722 | 3 | 0 | 3 |
| ARHGAP23 | DCPS | 0.670667 | 3 | 0 | 3 |
| ARHGAP23 | AP1S1 | 0.66679 | 3 | 0 | 3 |
| ARHGAP23 | CDK2AP1 | 0.659453 | 3 | 0 | 3 |
| ARHGAP23 | RDH10 | 0.657283 | 3 | 0 | 3 |
| ARHGAP23 | BAX | 0.645854 | 3 | 0 | 3 |
| ARHGAP23 | PRPF19 | 0.642213 | 3 | 0 | 3 |
| ARHGAP23 | FASTK | 0.63001 | 3 | 0 | 3 |
| ARHGAP23 | LPAR2 | 0.62907 | 3 | 0 | 3 |
| ARHGAP23 | INTS5 | 0.626071 | 4 | 0 | 3 |
| ARHGAP23 | ASF1B | 0.619522 | 4 | 0 | 3 |
| ARHGAP23 | C7orf26 | 0.613325 | 4 | 0 | 3 |
| ARHGAP23 | PSMB9 | 0.611802 | 3 | 0 | 3 |
| ARHGAP23 | ZFP64 | 0.611121 | 5 | 0 | 3 |
For details and further investigation, click here
