| Full name: zinc finger protein 621 | Alias Symbol: FLJ45246 | ||
| Type: protein-coding gene | Cytoband: 3p22.1 | ||
| Entrez ID: 285268 | HGNC ID: HGNC:24787 | Ensembl Gene: ENSG00000172888 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF621:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF621 | 285268 | 1558620_at | 0.0030 | 0.9922 | |
| GSE26886 | ZNF621 | 285268 | 1558620_at | 0.2600 | 0.2445 | |
| GSE45670 | ZNF621 | 285268 | 1558620_at | -0.1700 | 0.1714 | |
| GSE53622 | ZNF621 | 285268 | 59563 | 0.2069 | 0.4673 | |
| GSE53624 | ZNF621 | 285268 | 59563 | -0.0174 | 0.9244 | |
| GSE63941 | ZNF621 | 285268 | 1558620_at | -1.5964 | 0.0015 | |
| GSE77861 | ZNF621 | 285268 | 1558620_at | 0.0132 | 0.9633 | |
| GSE97050 | ZNF621 | 285268 | A_33_P3305158 | 0.0208 | 0.9865 | |
| SRP007169 | ZNF621 | 285268 | RNAseq | 0.5953 | 0.1342 | |
| SRP008496 | ZNF621 | 285268 | RNAseq | 0.7655 | 0.0095 | |
| SRP064894 | ZNF621 | 285268 | RNAseq | 0.0854 | 0.5611 | |
| SRP133303 | ZNF621 | 285268 | RNAseq | -0.0309 | 0.7161 | |
| SRP159526 | ZNF621 | 285268 | RNAseq | -0.0916 | 0.6496 | |
| SRP193095 | ZNF621 | 285268 | RNAseq | 0.0057 | 0.9569 | |
| SRP219564 | ZNF621 | 285268 | RNAseq | -0.1450 | 0.4830 | |
| TCGA | ZNF621 | 285268 | RNAseq | -0.2446 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZNF621 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF621:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF621 | 285268 | 0 | 19 | 11 | |
| GSE20123 | ZNF621 | 285268 | 0 | 19 | 11 | |
| GSE43470 | ZNF621 | 285268 | 0 | 20 | 23 | |
| GSE46452 | ZNF621 | 285268 | 2 | 17 | 40 | |
| GSE47630 | ZNF621 | 285268 | 2 | 24 | 14 | |
| GSE54993 | ZNF621 | 285268 | 7 | 2 | 61 | |
| GSE54994 | ZNF621 | 285268 | 1 | 33 | 19 | |
| GSE60625 | ZNF621 | 285268 | 5 | 0 | 6 | |
| GSE74703 | ZNF621 | 285268 | 0 | 16 | 20 | |
| GSE74704 | ZNF621 | 285268 | 0 | 13 | 7 | |
| TCGA | ZNF621 | 285268 | 1 | 71 | 24 |
Total number of gains: 18; Total number of losses: 234; Total Number of normals: 236.
Somatic mutations of ZNF621:
Generating mutation plots.
Highly correlated genes for ZNF621:
Showing top 20/31 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF621 | FAM71E1 | 0.857731 | 3 | 0 | 3 |
| ZNF621 | ZNF454 | 0.829265 | 3 | 0 | 3 |
| ZNF621 | DCAF8L2 | 0.821728 | 3 | 0 | 3 |
| ZNF621 | PSMD6 | 0.702884 | 4 | 0 | 3 |
| ZNF621 | MCM9 | 0.665139 | 6 | 0 | 5 |
| ZNF621 | CCDC96 | 0.662565 | 3 | 0 | 3 |
| ZNF621 | SERPINA11 | 0.635341 | 3 | 0 | 3 |
| ZNF621 | ZNF708 | 0.631492 | 4 | 0 | 4 |
| ZNF621 | TAPT1 | 0.62944 | 3 | 0 | 3 |
| ZNF621 | DYRK1A | 0.625401 | 4 | 0 | 3 |
| ZNF621 | FASTK | 0.620247 | 3 | 0 | 3 |
| ZNF621 | RC3H1 | 0.610564 | 3 | 0 | 3 |
| ZNF621 | LIG4 | 0.598043 | 3 | 0 | 3 |
| ZNF621 | PTPRN2 | 0.596463 | 5 | 0 | 4 |
| ZNF621 | VAMP4 | 0.590783 | 4 | 0 | 3 |
| ZNF621 | TENM4 | 0.571826 | 3 | 0 | 3 |
| ZNF621 | SCAP | 0.571558 | 5 | 0 | 4 |
| ZNF621 | MTERF2 | 0.568391 | 3 | 0 | 3 |
| ZNF621 | TP73-AS1 | 0.554475 | 4 | 0 | 3 |
| ZNF621 | NISCH | 0.553623 | 4 | 0 | 3 |
For details and further investigation, click here
