| Full name: cholecystokinin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p22.1 | ||
| Entrez ID: 885 | HGNC ID: HGNC:1569 | Ensembl Gene: ENSG00000187094 | OMIM ID: 118440 |
| Drug and gene relationship at DGIdb | |||
Expression of CCK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCK | 885 | 205827_at | -0.0540 | 0.8823 | |
| GSE20347 | CCK | 885 | 205827_at | 0.0504 | 0.6616 | |
| GSE23400 | CCK | 885 | 205827_at | -0.0232 | 0.5026 | |
| GSE26886 | CCK | 885 | 205827_at | -0.0193 | 0.9132 | |
| GSE29001 | CCK | 885 | 205827_at | -0.0282 | 0.8462 | |
| GSE38129 | CCK | 885 | 205827_at | 0.0176 | 0.8595 | |
| GSE45670 | CCK | 885 | 205827_at | 0.4069 | 0.0364 | |
| GSE63941 | CCK | 885 | 205827_at | -1.0685 | 0.0156 | |
| GSE77861 | CCK | 885 | 205827_at | 0.1290 | 0.6553 | |
| TCGA | CCK | 885 | RNAseq | -0.4607 | 0.6295 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CCK expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CCK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCK | 885 | 0 | 19 | 11 | |
| GSE20123 | CCK | 885 | 0 | 19 | 11 | |
| GSE43470 | CCK | 885 | 0 | 21 | 22 | |
| GSE46452 | CCK | 885 | 2 | 17 | 40 | |
| GSE47630 | CCK | 885 | 1 | 24 | 15 | |
| GSE54993 | CCK | 885 | 7 | 2 | 61 | |
| GSE54994 | CCK | 885 | 1 | 34 | 18 | |
| GSE60625 | CCK | 885 | 5 | 0 | 6 | |
| GSE74703 | CCK | 885 | 0 | 17 | 19 | |
| GSE74704 | CCK | 885 | 0 | 13 | 7 | |
| TCGA | CCK | 885 | 1 | 71 | 24 |
Total number of gains: 17; Total number of losses: 237; Total Number of normals: 234.
Somatic mutations of CCK:
Generating mutation plots.
Highly correlated genes for CCK:
Showing top 20/27 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCK | C14orf39 | 0.665099 | 3 | 0 | 3 |
| CCK | WNT2 | 0.620304 | 3 | 0 | 3 |
| CCK | SLC17A6 | 0.607429 | 3 | 0 | 3 |
| CCK | GPLD1 | 0.595113 | 3 | 0 | 3 |
| CCK | COL8A1 | 0.594632 | 3 | 0 | 3 |
| CCK | RBFADN | 0.594259 | 4 | 0 | 4 |
| CCK | MYO16 | 0.585781 | 3 | 0 | 3 |
| CCK | SZT2 | 0.582393 | 3 | 0 | 3 |
| CCK | SNORA78 | 0.581844 | 4 | 0 | 3 |
| CCK | NKX6-1 | 0.58074 | 3 | 0 | 3 |
| CCK | LINC01361 | 0.579777 | 4 | 0 | 3 |
| CCK | SLC22A18AS | 0.577125 | 4 | 0 | 3 |
| CCK | TMEM8B | 0.568116 | 3 | 0 | 3 |
| CCK | SLC17A7 | 0.547523 | 4 | 0 | 3 |
| CCK | PPP1R15A | 0.544987 | 6 | 0 | 3 |
| CCK | SERPIND1 | 0.544673 | 4 | 0 | 3 |
| CCK | MLN | 0.534544 | 6 | 0 | 3 |
| CCK | ABCG5 | 0.532865 | 4 | 0 | 3 |
| CCK | AMPH | 0.531643 | 4 | 0 | 3 |
| CCK | PPM1E | 0.530558 | 4 | 0 | 3 |
For details and further investigation, click here
