| Full name: solute carrier family 17 member 6 | Alias Symbol: DNPI|VGLUT2 | ||
| Type: protein-coding gene | Cytoband: 11p14.3 | ||
| Entrez ID: 57084 | HGNC ID: HGNC:16703 | Ensembl Gene: ENSG00000091664 | OMIM ID: 607563 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC17A6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC17A6 | 57084 | 220551_at | 0.0546 | 0.8219 | |
| GSE20347 | SLC17A6 | 57084 | 220551_at | 0.0509 | 0.2840 | |
| GSE23400 | SLC17A6 | 57084 | 220551_at | 0.0163 | 0.4700 | |
| GSE26886 | SLC17A6 | 57084 | 220551_at | -0.0127 | 0.9183 | |
| GSE29001 | SLC17A6 | 57084 | 220551_at | 0.1080 | 0.6058 | |
| GSE38129 | SLC17A6 | 57084 | 220551_at | -0.0194 | 0.7551 | |
| GSE45670 | SLC17A6 | 57084 | 220551_at | -0.0010 | 0.9903 | |
| GSE53622 | SLC17A6 | 57084 | 101039 | 0.5190 | 0.0002 | |
| GSE53624 | SLC17A6 | 57084 | 101039 | 0.5226 | 0.0000 | |
| GSE63941 | SLC17A6 | 57084 | 220551_at | -0.0658 | 0.7351 | |
| GSE77861 | SLC17A6 | 57084 | 220551_at | 0.0264 | 0.7423 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC17A6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC17A6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC17A6 | 57084 | 0 | 11 | 19 | |
| GSE20123 | SLC17A6 | 57084 | 0 | 11 | 19 | |
| GSE43470 | SLC17A6 | 57084 | 1 | 6 | 36 | |
| GSE46452 | SLC17A6 | 57084 | 7 | 5 | 47 | |
| GSE47630 | SLC17A6 | 57084 | 3 | 10 | 27 | |
| GSE54993 | SLC17A6 | 57084 | 3 | 0 | 67 | |
| GSE54994 | SLC17A6 | 57084 | 3 | 12 | 38 | |
| GSE60625 | SLC17A6 | 57084 | 0 | 0 | 11 | |
| GSE74703 | SLC17A6 | 57084 | 1 | 4 | 31 | |
| GSE74704 | SLC17A6 | 57084 | 0 | 9 | 11 | |
| TCGA | SLC17A6 | 57084 | 12 | 24 | 60 |
Total number of gains: 30; Total number of losses: 92; Total Number of normals: 366.
Somatic mutations of SLC17A6:
Generating mutation plots.
Highly correlated genes for SLC17A6:
Showing top 20/33 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC17A6 | LINC01393 | 0.682732 | 3 | 0 | 3 |
| SLC17A6 | PPM1E | 0.678017 | 3 | 0 | 3 |
| SLC17A6 | SLC7A10 | 0.675345 | 3 | 0 | 3 |
| SLC17A6 | APLP1 | 0.642694 | 3 | 0 | 3 |
| SLC17A6 | SORCS3 | 0.630679 | 3 | 0 | 3 |
| SLC17A6 | IFNA7 | 0.622231 | 3 | 0 | 3 |
| SLC17A6 | FRS3 | 0.620538 | 3 | 0 | 3 |
| SLC17A6 | PRDM9 | 0.61285 | 5 | 0 | 4 |
| SLC17A6 | KCNIP2 | 0.610043 | 4 | 0 | 4 |
| SLC17A6 | CCK | 0.607429 | 3 | 0 | 3 |
| SLC17A6 | LINC01361 | 0.604538 | 4 | 0 | 3 |
| SLC17A6 | CCR8 | 0.602513 | 4 | 0 | 3 |
| SLC17A6 | CLDN9 | 0.595789 | 3 | 0 | 3 |
| SLC17A6 | CKM | 0.589743 | 3 | 0 | 3 |
| SLC17A6 | KRT84 | 0.580661 | 5 | 0 | 3 |
| SLC17A6 | GRIN2C | 0.580104 | 3 | 0 | 3 |
| SLC17A6 | SLC17A2 | 0.578939 | 4 | 0 | 3 |
| SLC17A6 | B3GNT4 | 0.574781 | 3 | 0 | 3 |
| SLC17A6 | IFNA14 | 0.571332 | 4 | 0 | 4 |
| SLC17A6 | TAS2R4 | 0.569478 | 5 | 0 | 3 |
For details and further investigation, click here
