| Full name: myosin XVI | Alias Symbol: MYR8|KIAA0865|Myo16b|NYAP3|PPP1R107 | ||
| Type: protein-coding gene | Cytoband: 13q33.3 | ||
| Entrez ID: 23026 | HGNC ID: HGNC:29822 | Ensembl Gene: ENSG00000041515 | OMIM ID: 615479 |
| Drug and gene relationship at DGIdb | |||
Expression of MYO16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYO16 | 23026 | 215119_at | -0.2219 | 0.8440 | |
| GSE20347 | MYO16 | 23026 | 215119_at | 0.0756 | 0.4197 | |
| GSE23400 | MYO16 | 23026 | 215119_at | -0.2106 | 0.0001 | |
| GSE26886 | MYO16 | 23026 | 1557720_s_at | -0.0463 | 0.7489 | |
| GSE29001 | MYO16 | 23026 | 215119_at | -0.0706 | 0.7702 | |
| GSE38129 | MYO16 | 23026 | 215119_at | -0.3858 | 0.0155 | |
| GSE45670 | MYO16 | 23026 | 1557720_s_at | -0.0572 | 0.6753 | |
| GSE53622 | MYO16 | 23026 | 12223 | -0.8483 | 0.0030 | |
| GSE53624 | MYO16 | 23026 | 12223 | -0.8683 | 0.0000 | |
| GSE63941 | MYO16 | 23026 | 215119_at | -0.2027 | 0.2584 | |
| GSE77861 | MYO16 | 23026 | 1557720_s_at | -0.2123 | 0.0341 | |
| SRP133303 | MYO16 | 23026 | RNAseq | -0.0465 | 0.8669 | |
| SRP159526 | MYO16 | 23026 | RNAseq | -0.5559 | 0.3368 | |
| TCGA | MYO16 | 23026 | RNAseq | -0.4128 | 0.2399 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MYO16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYO16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYO16 | 23026 | 6 | 12 | 12 | |
| GSE20123 | MYO16 | 23026 | 6 | 11 | 13 | |
| GSE43470 | MYO16 | 23026 | 4 | 13 | 26 | |
| GSE46452 | MYO16 | 23026 | 2 | 31 | 26 | |
| GSE47630 | MYO16 | 23026 | 3 | 26 | 11 | |
| GSE54993 | MYO16 | 23026 | 11 | 4 | 55 | |
| GSE54994 | MYO16 | 23026 | 8 | 8 | 37 | |
| GSE60625 | MYO16 | 23026 | 0 | 3 | 8 | |
| GSE74703 | MYO16 | 23026 | 3 | 9 | 24 | |
| GSE74704 | MYO16 | 23026 | 4 | 10 | 6 | |
| TCGA | MYO16 | 23026 | 19 | 33 | 44 |
Total number of gains: 66; Total number of losses: 160; Total Number of normals: 262.
Somatic mutations of MYO16:
Generating mutation plots.
Highly correlated genes for MYO16:
Showing top 20/411 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYO16 | SNAP91 | 0.701783 | 5 | 0 | 4 |
| MYO16 | CHD5 | 0.689529 | 4 | 0 | 4 |
| MYO16 | CD5L | 0.675235 | 3 | 0 | 3 |
| MYO16 | USH1C | 0.66893 | 4 | 0 | 4 |
| MYO16 | FEZF2 | 0.668858 | 3 | 0 | 3 |
| MYO16 | PTPRU | 0.667461 | 3 | 0 | 3 |
| MYO16 | TCL6 | 0.666654 | 3 | 0 | 3 |
| MYO16 | ASTN1 | 0.66176 | 5 | 0 | 5 |
| MYO16 | TMEM8B | 0.658595 | 5 | 0 | 5 |
| MYO16 | DMRTB1 | 0.653743 | 3 | 0 | 3 |
| MYO16 | GLYAT | 0.65263 | 3 | 0 | 3 |
| MYO16 | PPP1R1A | 0.649292 | 5 | 0 | 5 |
| MYO16 | ITGB1BP2 | 0.647284 | 5 | 0 | 4 |
| MYO16 | KCNN2 | 0.646137 | 3 | 0 | 3 |
| MYO16 | SLN | 0.644713 | 5 | 0 | 3 |
| MYO16 | SCGN | 0.64165 | 3 | 0 | 3 |
| MYO16 | KCNC1 | 0.635579 | 3 | 0 | 3 |
| MYO16 | CDC42EP2 | 0.635486 | 4 | 0 | 4 |
| MYO16 | KIF5C | 0.634013 | 4 | 0 | 4 |
| MYO16 | NKX6-1 | 0.633406 | 7 | 0 | 6 |
For details and further investigation, click here
