| Full name: CCM2 like scaffold protein | Alias Symbol: dJ310O13.5 | ||
| Type: protein-coding gene | Cytoband: 20q11.21 | ||
| Entrez ID: 140706 | HGNC ID: HGNC:16153 | Ensembl Gene: ENSG00000101331 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCM2L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCM2L | 140706 | 1570070_at | -0.0110 | 0.9700 | |
| GSE26886 | CCM2L | 140706 | 1570070_at | -0.0958 | 0.3438 | |
| GSE45670 | CCM2L | 140706 | 1570070_at | 0.0237 | 0.8250 | |
| GSE53622 | CCM2L | 140706 | 1656 | -0.1005 | 0.0557 | |
| GSE53624 | CCM2L | 140706 | 1656 | 0.0442 | 0.4553 | |
| GSE63941 | CCM2L | 140706 | 1570070_at | 0.3632 | 0.0045 | |
| GSE77861 | CCM2L | 140706 | 1570070_at | -0.0283 | 0.8256 | |
| SRP064894 | CCM2L | 140706 | RNAseq | 0.3859 | 0.2880 | |
| SRP133303 | CCM2L | 140706 | RNAseq | -1.1044 | 0.0001 | |
| SRP159526 | CCM2L | 140706 | RNAseq | -0.4035 | 0.4099 | |
| SRP219564 | CCM2L | 140706 | RNAseq | -0.3632 | 0.5326 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CCM2L expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CCM2L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCM2L | 140706 | 15 | 0 | 15 | |
| GSE20123 | CCM2L | 140706 | 15 | 0 | 15 | |
| GSE43470 | CCM2L | 140706 | 11 | 0 | 32 | |
| GSE46452 | CCM2L | 140706 | 29 | 0 | 30 | |
| GSE47630 | CCM2L | 140706 | 25 | 0 | 15 | |
| GSE54993 | CCM2L | 140706 | 0 | 18 | 52 | |
| GSE54994 | CCM2L | 140706 | 27 | 1 | 25 | |
| GSE60625 | CCM2L | 140706 | 0 | 0 | 11 | |
| GSE74703 | CCM2L | 140706 | 10 | 0 | 26 | |
| GSE74704 | CCM2L | 140706 | 10 | 0 | 10 | |
| TCGA | CCM2L | 140706 | 49 | 1 | 46 |
Total number of gains: 191; Total number of losses: 20; Total Number of normals: 277.
Somatic mutations of CCM2L:
Generating mutation plots.
Highly correlated genes for CCM2L:
Showing top 20/48 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCM2L | LCE1E | 0.648556 | 4 | 0 | 3 |
| CCM2L | ACTL7B | 0.616867 | 3 | 0 | 3 |
| CCM2L | LINC00944 | 0.611865 | 3 | 0 | 3 |
| CCM2L | FGA | 0.608524 | 3 | 0 | 3 |
| CCM2L | SORCS3-AS1 | 0.596876 | 3 | 0 | 3 |
| CCM2L | TAT | 0.592276 | 4 | 0 | 4 |
| CCM2L | SCN10A | 0.591368 | 5 | 0 | 4 |
| CCM2L | MRGPRX2 | 0.586194 | 3 | 0 | 3 |
| CCM2L | NRAP | 0.583294 | 4 | 0 | 3 |
| CCM2L | ASB12 | 0.5812 | 5 | 0 | 4 |
| CCM2L | WFDC9 | 0.580795 | 3 | 0 | 3 |
| CCM2L | TMEM72-AS1 | 0.578962 | 3 | 0 | 3 |
| CCM2L | LINC00520 | 0.572133 | 4 | 0 | 3 |
| CCM2L | MIR4500HG | 0.570819 | 4 | 0 | 3 |
| CCM2L | OR51B2 | 0.57052 | 3 | 0 | 3 |
| CCM2L | LINC00930 | 0.568842 | 5 | 0 | 4 |
| CCM2L | C8orf74 | 0.567284 | 3 | 0 | 3 |
| CCM2L | CYP2A7 | 0.566173 | 3 | 0 | 3 |
| CCM2L | PDE6G | 0.566147 | 3 | 0 | 3 |
| CCM2L | OR6A2 | 0.564355 | 5 | 0 | 5 |
For details and further investigation, click here
