| Full name: MAS related GPR family member X2 | Alias Symbol: MRGX2 | ||
| Type: protein-coding gene | Cytoband: 11p15.1 | ||
| Entrez ID: 117194 | HGNC ID: HGNC:17983 | Ensembl Gene: ENSG00000183695 | OMIM ID: 607228 |
| Drug and gene relationship at DGIdb | |||
Expression of MRGPRX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRGPRX2 | 117194 | 1553889_at | -0.1665 | 0.5545 | |
| GSE26886 | MRGPRX2 | 117194 | 1553889_at | -0.2030 | 0.1382 | |
| GSE45670 | MRGPRX2 | 117194 | 1553889_at | -0.0610 | 0.6706 | |
| GSE53622 | MRGPRX2 | 117194 | 135170 | -0.3325 | 0.0015 | |
| GSE53624 | MRGPRX2 | 117194 | 135170 | -0.3858 | 0.0000 | |
| GSE63941 | MRGPRX2 | 117194 | 1553889_at | 0.0662 | 0.6164 | |
| GSE77861 | MRGPRX2 | 117194 | 1553889_at | -0.2288 | 0.0253 | |
| TCGA | MRGPRX2 | 117194 | RNAseq | -0.4703 | 0.5982 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRGPRX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRGPRX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRGPRX2 | 117194 | 0 | 10 | 20 | |
| GSE20123 | MRGPRX2 | 117194 | 0 | 10 | 20 | |
| GSE43470 | MRGPRX2 | 117194 | 1 | 5 | 37 | |
| GSE46452 | MRGPRX2 | 117194 | 7 | 5 | 47 | |
| GSE47630 | MRGPRX2 | 117194 | 3 | 10 | 27 | |
| GSE54993 | MRGPRX2 | 117194 | 3 | 0 | 67 | |
| GSE54994 | MRGPRX2 | 117194 | 3 | 12 | 38 | |
| GSE60625 | MRGPRX2 | 117194 | 0 | 0 | 11 | |
| GSE74703 | MRGPRX2 | 117194 | 1 | 3 | 32 | |
| GSE74704 | MRGPRX2 | 117194 | 0 | 9 | 11 | |
| TCGA | MRGPRX2 | 117194 | 12 | 28 | 56 |
Total number of gains: 30; Total number of losses: 92; Total Number of normals: 366.
Somatic mutations of MRGPRX2:
Generating mutation plots.
Highly correlated genes for MRGPRX2:
Showing top 20/107 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRGPRX2 | STPG2 | 0.695284 | 3 | 0 | 3 |
| MRGPRX2 | E2F4 | 0.694789 | 3 | 0 | 3 |
| MRGPRX2 | C5orf47 | 0.685448 | 4 | 0 | 4 |
| MRGPRX2 | LINC00317 | 0.685447 | 4 | 0 | 4 |
| MRGPRX2 | NRAP | 0.67333 | 5 | 0 | 4 |
| MRGPRX2 | CRADD | 0.669683 | 3 | 0 | 3 |
| MRGPRX2 | OR51M1 | 0.666466 | 4 | 0 | 4 |
| MRGPRX2 | GUCY2D | 0.663498 | 3 | 0 | 3 |
| MRGPRX2 | DEFB119 | 0.657959 | 3 | 0 | 3 |
| MRGPRX2 | ALLC | 0.655819 | 3 | 0 | 3 |
| MRGPRX2 | LIMD1-AS1 | 0.652022 | 4 | 0 | 4 |
| MRGPRX2 | DNAH1 | 0.648754 | 4 | 0 | 3 |
| MRGPRX2 | MVK | 0.647057 | 4 | 0 | 4 |
| MRGPRX2 | RARG | 0.645126 | 4 | 0 | 4 |
| MRGPRX2 | MT4 | 0.644774 | 3 | 0 | 3 |
| MRGPRX2 | SSTR4 | 0.641852 | 3 | 0 | 3 |
| MRGPRX2 | OTOP2 | 0.641225 | 3 | 0 | 3 |
| MRGPRX2 | ANKRD31 | 0.640628 | 3 | 0 | 3 |
| MRGPRX2 | LYNX1 | 0.639615 | 3 | 0 | 3 |
| MRGPRX2 | TSSK2 | 0.637533 | 4 | 0 | 3 |
For details and further investigation, click here
