| Full name: actin like 7B | Alias Symbol: Tact1 | ||
| Type: protein-coding gene | Cytoband: 9q31.3 | ||
| Entrez ID: 10880 | HGNC ID: HGNC:162 | Ensembl Gene: ENSG00000148156 | OMIM ID: 604304 |
| Drug and gene relationship at DGIdb | |||
Expression of ACTL7B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACTL7B | 10880 | 220498_at | -0.0083 | 0.9816 | |
| GSE20347 | ACTL7B | 10880 | 220498_at | -0.0933 | 0.1336 | |
| GSE23400 | ACTL7B | 10880 | 220498_at | -0.1023 | 0.0003 | |
| GSE26886 | ACTL7B | 10880 | 220498_at | -0.0269 | 0.8527 | |
| GSE29001 | ACTL7B | 10880 | 220498_at | 0.0064 | 0.9610 | |
| GSE38129 | ACTL7B | 10880 | 220498_at | -0.0868 | 0.1868 | |
| GSE45670 | ACTL7B | 10880 | 220498_at | 0.0623 | 0.4158 | |
| GSE53622 | ACTL7B | 10880 | 163780 | -0.3324 | 0.0105 | |
| GSE53624 | ACTL7B | 10880 | 163780 | -0.1488 | 0.2964 | |
| GSE63941 | ACTL7B | 10880 | 220498_at | 0.2412 | 0.1208 | |
| GSE77861 | ACTL7B | 10880 | 220498_at | -0.1781 | 0.1071 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ACTL7B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACTL7B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACTL7B | 10880 | 4 | 9 | 17 | |
| GSE20123 | ACTL7B | 10880 | 5 | 8 | 17 | |
| GSE43470 | ACTL7B | 10880 | 7 | 3 | 33 | |
| GSE46452 | ACTL7B | 10880 | 6 | 13 | 40 | |
| GSE47630 | ACTL7B | 10880 | 3 | 16 | 21 | |
| GSE54993 | ACTL7B | 10880 | 3 | 3 | 64 | |
| GSE54994 | ACTL7B | 10880 | 9 | 10 | 34 | |
| GSE60625 | ACTL7B | 10880 | 0 | 0 | 11 | |
| GSE74703 | ACTL7B | 10880 | 6 | 3 | 27 | |
| GSE74704 | ACTL7B | 10880 | 2 | 6 | 12 | |
| TCGA | ACTL7B | 10880 | 27 | 21 | 48 |
Total number of gains: 72; Total number of losses: 92; Total Number of normals: 324.
Somatic mutations of ACTL7B:
Generating mutation plots.
Highly correlated genes for ACTL7B:
Showing top 20/146 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACTL7B | DNMT3L | 0.694579 | 3 | 0 | 3 |
| ACTL7B | HAMP | 0.685378 | 3 | 0 | 3 |
| ACTL7B | MAPK11 | 0.683287 | 3 | 0 | 3 |
| ACTL7B | KCNT1 | 0.655555 | 3 | 0 | 3 |
| ACTL7B | GSX2 | 0.65261 | 4 | 0 | 3 |
| ACTL7B | AMBRA1 | 0.634107 | 5 | 0 | 3 |
| ACTL7B | ACTL6B | 0.630663 | 5 | 0 | 5 |
| ACTL7B | TMEM184A | 0.629896 | 3 | 0 | 3 |
| ACTL7B | CTSE | 0.629564 | 3 | 0 | 3 |
| ACTL7B | VGF | 0.628155 | 5 | 0 | 4 |
| ACTL7B | CCL24 | 0.622493 | 4 | 0 | 4 |
| ACTL7B | CACNG3 | 0.619981 | 4 | 0 | 3 |
| ACTL7B | CCM2L | 0.616867 | 3 | 0 | 3 |
| ACTL7B | CYP2D6 | 0.615691 | 5 | 0 | 4 |
| ACTL7B | TBXA2R | 0.615073 | 4 | 0 | 3 |
| ACTL7B | G6PC2 | 0.612831 | 4 | 0 | 4 |
| ACTL7B | RBP4 | 0.610727 | 3 | 0 | 3 |
| ACTL7B | CHRNG | 0.610692 | 4 | 0 | 3 |
| ACTL7B | ITIH1 | 0.609381 | 3 | 0 | 3 |
| ACTL7B | SPIN2A | 0.608785 | 5 | 0 | 4 |
For details and further investigation, click here
