| Full name: cyclin G1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q34 | ||
| Entrez ID: 900 | HGNC ID: HGNC:1592 | Ensembl Gene: ENSG00000113328 | OMIM ID: 601578 |
| Drug and gene relationship at DGIdb | |||
CCNG1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04115 | p53 signaling pathway |
Expression of CCNG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCNG1 | 900 | 208796_s_at | -0.7505 | 0.0148 | |
| GSE20347 | CCNG1 | 900 | 208796_s_at | -0.9326 | 0.0000 | |
| GSE23400 | CCNG1 | 900 | 208796_s_at | -0.6071 | 0.0000 | |
| GSE26886 | CCNG1 | 900 | 208796_s_at | -0.2643 | 0.3976 | |
| GSE29001 | CCNG1 | 900 | 208796_s_at | -0.8351 | 0.0514 | |
| GSE38129 | CCNG1 | 900 | 208796_s_at | -0.9962 | 0.0000 | |
| GSE45670 | CCNG1 | 900 | 208796_s_at | -1.0308 | 0.0000 | |
| GSE53622 | CCNG1 | 900 | 109385 | -0.8594 | 0.0000 | |
| GSE53624 | CCNG1 | 900 | 109385 | -1.0033 | 0.0000 | |
| GSE63941 | CCNG1 | 900 | 208796_s_at | -1.2888 | 0.0256 | |
| GSE77861 | CCNG1 | 900 | 208796_s_at | -1.0967 | 0.0147 | |
| GSE97050 | CCNG1 | 900 | A_23_P58606 | -0.6352 | 0.1382 | |
| SRP007169 | CCNG1 | 900 | RNAseq | -1.7975 | 0.0001 | |
| SRP008496 | CCNG1 | 900 | RNAseq | -1.7785 | 0.0000 | |
| SRP064894 | CCNG1 | 900 | RNAseq | -0.8037 | 0.0001 | |
| SRP133303 | CCNG1 | 900 | RNAseq | -0.7506 | 0.0000 | |
| SRP159526 | CCNG1 | 900 | RNAseq | -1.0111 | 0.0013 | |
| SRP193095 | CCNG1 | 900 | RNAseq | -1.3339 | 0.0000 | |
| SRP219564 | CCNG1 | 900 | RNAseq | -0.8051 | 0.0043 | |
| TCGA | CCNG1 | 900 | RNAseq | -0.3965 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by CCNG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCNG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCNG1 | 900 | 0 | 12 | 18 | |
| GSE20123 | CCNG1 | 900 | 0 | 12 | 18 | |
| GSE43470 | CCNG1 | 900 | 2 | 10 | 31 | |
| GSE46452 | CCNG1 | 900 | 0 | 27 | 32 | |
| GSE47630 | CCNG1 | 900 | 0 | 20 | 20 | |
| GSE54993 | CCNG1 | 900 | 9 | 2 | 59 | |
| GSE54994 | CCNG1 | 900 | 2 | 15 | 36 | |
| GSE60625 | CCNG1 | 900 | 1 | 0 | 10 | |
| GSE74703 | CCNG1 | 900 | 2 | 8 | 26 | |
| GSE74704 | CCNG1 | 900 | 0 | 7 | 13 | |
| TCGA | CCNG1 | 900 | 5 | 38 | 53 |
Total number of gains: 21; Total number of losses: 151; Total Number of normals: 316.
Somatic mutations of CCNG1:
Generating mutation plots.
Highly correlated genes for CCNG1:
Showing top 20/1573 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCNG1 | EIF4E3 | 0.763721 | 7 | 0 | 6 |
| CCNG1 | C1QTNF7 | 0.753381 | 5 | 0 | 5 |
| CCNG1 | RAP1A | 0.752064 | 12 | 0 | 11 |
| CCNG1 | CLEC3B | 0.742333 | 3 | 0 | 3 |
| CCNG1 | KIAA1328 | 0.739787 | 3 | 0 | 3 |
| CCNG1 | KCTD6 | 0.739502 | 6 | 0 | 6 |
| CCNG1 | ZNF662 | 0.735174 | 6 | 0 | 6 |
| CCNG1 | SORCS1 | 0.73498 | 4 | 0 | 4 |
| CCNG1 | GPRASP2 | 0.734083 | 3 | 0 | 3 |
| CCNG1 | CYP21A2 | 0.733156 | 3 | 0 | 3 |
| CCNG1 | NFIA | 0.731328 | 7 | 0 | 7 |
| CCNG1 | LMBRD1 | 0.729851 | 11 | 0 | 10 |
| CCNG1 | VIT | 0.729133 | 6 | 0 | 6 |
| CCNG1 | BRK1 | 0.724293 | 6 | 0 | 6 |
| CCNG1 | TMEM114 | 0.721146 | 3 | 0 | 3 |
| CCNG1 | DDAH1 | 0.720544 | 11 | 0 | 11 |
| CCNG1 | SLC4A4 | 0.718095 | 6 | 0 | 5 |
| CCNG1 | KIAA1191 | 0.71809 | 7 | 0 | 5 |
| CCNG1 | SRI | 0.71733 | 3 | 0 | 3 |
| CCNG1 | ANKRD6 | 0.715642 | 3 | 0 | 3 |
For details and further investigation, click here
