| Full name: chaperonin containing TCP1 subunit 6B | Alias Symbol: Cctz2|TSA303 | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 10693 | HGNC ID: HGNC:1621 | Ensembl Gene: ENSG00000132141 | OMIM ID: 610730 |
| Drug and gene relationship at DGIdb | |||
Expression of CCT6B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCT6B | 10693 | 206587_at | -0.5182 | 0.1242 | |
| GSE20347 | CCT6B | 10693 | 206587_at | -0.0516 | 0.7142 | |
| GSE23400 | CCT6B | 10693 | 206587_at | 0.0076 | 0.8330 | |
| GSE26886 | CCT6B | 10693 | 206587_at | -0.6365 | 0.0277 | |
| GSE29001 | CCT6B | 10693 | 206587_at | -0.0920 | 0.7625 | |
| GSE38129 | CCT6B | 10693 | 206587_at | -0.0336 | 0.8016 | |
| GSE45670 | CCT6B | 10693 | 206587_at | -0.4244 | 0.0044 | |
| GSE53622 | CCT6B | 10693 | 34308 | -1.0287 | 0.0000 | |
| GSE53624 | CCT6B | 10693 | 34308 | -0.5841 | 0.0000 | |
| GSE63941 | CCT6B | 10693 | 206587_at | -0.7148 | 0.3227 | |
| GSE77861 | CCT6B | 10693 | 206587_at | 0.0135 | 0.9219 | |
| SRP064894 | CCT6B | 10693 | RNAseq | -0.6836 | 0.0055 | |
| SRP133303 | CCT6B | 10693 | RNAseq | -0.6459 | 0.0039 | |
| SRP159526 | CCT6B | 10693 | RNAseq | -0.5969 | 0.3094 | |
| SRP193095 | CCT6B | 10693 | RNAseq | -0.6296 | 0.0009 | |
| SRP219564 | CCT6B | 10693 | RNAseq | -0.4347 | 0.1701 | |
| TCGA | CCT6B | 10693 | RNAseq | -0.5079 | 0.0149 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CCT6B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCT6B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCT6B | 10693 | 5 | 1 | 24 | |
| GSE20123 | CCT6B | 10693 | 5 | 1 | 24 | |
| GSE43470 | CCT6B | 10693 | 1 | 2 | 40 | |
| GSE46452 | CCT6B | 10693 | 34 | 0 | 25 | |
| GSE47630 | CCT6B | 10693 | 7 | 1 | 32 | |
| GSE54993 | CCT6B | 10693 | 3 | 3 | 64 | |
| GSE54994 | CCT6B | 10693 | 8 | 6 | 39 | |
| GSE60625 | CCT6B | 10693 | 4 | 0 | 7 | |
| GSE74703 | CCT6B | 10693 | 1 | 1 | 34 | |
| GSE74704 | CCT6B | 10693 | 3 | 1 | 16 | |
| TCGA | CCT6B | 10693 | 20 | 9 | 67 |
Total number of gains: 91; Total number of losses: 25; Total Number of normals: 372.
Somatic mutations of CCT6B:
Generating mutation plots.
Highly correlated genes for CCT6B:
Showing top 20/262 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCT6B | AP4B1 | 0.700603 | 3 | 0 | 3 |
| CCT6B | SLTM | 0.68202 | 3 | 0 | 3 |
| CCT6B | FDX1 | 0.642448 | 5 | 0 | 4 |
| CCT6B | FBXW11 | 0.638993 | 4 | 0 | 3 |
| CCT6B | CPVL | 0.637984 | 4 | 0 | 4 |
| CCT6B | CDKN2AIP | 0.637952 | 4 | 0 | 3 |
| CCT6B | CLCN3 | 0.632401 | 3 | 0 | 3 |
| CCT6B | ALAD | 0.62873 | 4 | 0 | 3 |
| CCT6B | IK | 0.623475 | 4 | 0 | 4 |
| CCT6B | CPEB4 | 0.6222 | 3 | 0 | 3 |
| CCT6B | SYNRG | 0.620724 | 3 | 0 | 3 |
| CCT6B | SHE | 0.620602 | 3 | 0 | 3 |
| CCT6B | FAM174A | 0.61982 | 4 | 0 | 3 |
| CCT6B | AK3 | 0.616996 | 5 | 0 | 5 |
| CCT6B | MMRN1 | 0.615559 | 4 | 0 | 3 |
| CCT6B | CIPC | 0.610485 | 4 | 0 | 3 |
| CCT6B | TMOD2 | 0.607829 | 3 | 0 | 3 |
| CCT6B | FAM122A | 0.607715 | 5 | 0 | 3 |
| CCT6B | IDE | 0.605341 | 6 | 0 | 5 |
| CCT6B | DYNLT3 | 0.604479 | 4 | 0 | 3 |
For details and further investigation, click here
