| Full name: multimerin 1 | Alias Symbol: ECM|EMILIN4|GPIa* | ||
| Type: protein-coding gene | Cytoband: 4q22.1 | ||
| Entrez ID: 22915 | HGNC ID: HGNC:7178 | Ensembl Gene: ENSG00000138722 | OMIM ID: 601456 |
| Drug and gene relationship at DGIdb | |||
Expression of MMRN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MMRN1 | 22915 | 205612_at | -1.9447 | 0.0736 | |
| GSE20347 | MMRN1 | 22915 | 205612_at | -0.1406 | 0.4528 | |
| GSE23400 | MMRN1 | 22915 | 205612_at | -0.1580 | 0.0015 | |
| GSE26886 | MMRN1 | 22915 | 205612_at | -0.1345 | 0.6157 | |
| GSE29001 | MMRN1 | 22915 | 205612_at | -0.2811 | 0.0642 | |
| GSE38129 | MMRN1 | 22915 | 205612_at | -0.7235 | 0.0077 | |
| GSE45670 | MMRN1 | 22915 | 205612_at | -2.2413 | 0.0001 | |
| GSE53622 | MMRN1 | 22915 | 51282 | -3.0105 | 0.0000 | |
| GSE53624 | MMRN1 | 22915 | 51282 | -2.6546 | 0.0000 | |
| GSE63941 | MMRN1 | 22915 | 205612_at | 0.0136 | 0.9238 | |
| GSE77861 | MMRN1 | 22915 | 205612_at | 0.0255 | 0.8429 | |
| GSE97050 | MMRN1 | 22915 | A_33_P3212257 | -0.5258 | 0.3842 | |
| SRP007169 | MMRN1 | 22915 | RNAseq | -0.3736 | 0.5104 | |
| SRP064894 | MMRN1 | 22915 | RNAseq | -0.7482 | 0.2164 | |
| SRP133303 | MMRN1 | 22915 | RNAseq | -2.7559 | 0.0000 | |
| SRP159526 | MMRN1 | 22915 | RNAseq | -0.5675 | 0.5519 | |
| SRP219564 | MMRN1 | 22915 | RNAseq | -1.7063 | 0.0591 | |
| TCGA | MMRN1 | 22915 | RNAseq | -1.4608 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by MMRN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MMRN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MMRN1 | 22915 | 0 | 13 | 17 | |
| GSE20123 | MMRN1 | 22915 | 0 | 13 | 17 | |
| GSE43470 | MMRN1 | 22915 | 0 | 13 | 30 | |
| GSE46452 | MMRN1 | 22915 | 1 | 36 | 22 | |
| GSE47630 | MMRN1 | 22915 | 0 | 20 | 20 | |
| GSE54993 | MMRN1 | 22915 | 8 | 0 | 62 | |
| GSE54994 | MMRN1 | 22915 | 2 | 10 | 41 | |
| GSE60625 | MMRN1 | 22915 | 3 | 0 | 8 | |
| GSE74703 | MMRN1 | 22915 | 0 | 11 | 25 | |
| GSE74704 | MMRN1 | 22915 | 0 | 8 | 12 | |
| TCGA | MMRN1 | 22915 | 11 | 36 | 49 |
Total number of gains: 25; Total number of losses: 160; Total Number of normals: 303.
Somatic mutations of MMRN1:
Generating mutation plots.
Highly correlated genes for MMRN1:
Showing top 20/1081 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MMRN1 | GIMAP5 | 0.82991 | 3 | 0 | 3 |
| MMRN1 | CLEC3B | 0.823728 | 3 | 0 | 3 |
| MMRN1 | PDE7B | 0.801855 | 5 | 0 | 5 |
| MMRN1 | SHE | 0.769149 | 5 | 0 | 5 |
| MMRN1 | LINC01082 | 0.76711 | 4 | 0 | 4 |
| MMRN1 | CYP4V2 | 0.763315 | 3 | 0 | 3 |
| MMRN1 | MYCT1 | 0.762245 | 6 | 0 | 6 |
| MMRN1 | TEK | 0.761747 | 6 | 0 | 5 |
| MMRN1 | LYVE1 | 0.760855 | 9 | 0 | 8 |
| MMRN1 | SMTNL2 | 0.759873 | 5 | 0 | 5 |
| MMRN1 | OGN | 0.757673 | 9 | 0 | 8 |
| MMRN1 | CYP2U1 | 0.755713 | 4 | 0 | 4 |
| MMRN1 | CNRIP1 | 0.754692 | 6 | 0 | 6 |
| MMRN1 | CYP21A2 | 0.754396 | 3 | 0 | 3 |
| MMRN1 | GAB1 | 0.753973 | 4 | 0 | 4 |
| MMRN1 | TFPI | 0.747934 | 8 | 0 | 7 |
| MMRN1 | SLC16A4 | 0.747784 | 7 | 0 | 6 |
| MMRN1 | NR2F1 | 0.747319 | 3 | 0 | 3 |
| MMRN1 | NEK7 | 0.746988 | 3 | 0 | 3 |
| MMRN1 | ACKR1 | 0.74537 | 9 | 0 | 9 |
For details and further investigation, click here
