| Full name: CD209 molecule | Alias Symbol: DC-SIGN|CDSIGN|DC-SIGN1|CLEC4L | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 30835 | HGNC ID: HGNC:1641 | Ensembl Gene: ENSG00000090659 | OMIM ID: 604672 |
| Drug and gene relationship at DGIdb | |||
CD209 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05152 | Tuberculosis |
Expression of CD209:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD209 | 30835 | 207277_at | -0.7050 | 0.3413 | |
| GSE20347 | CD209 | 30835 | 207278_s_at | -0.1004 | 0.1855 | |
| GSE23400 | CD209 | 30835 | 207277_at | -0.1778 | 0.0001 | |
| GSE26886 | CD209 | 30835 | 207277_at | -0.1131 | 0.5869 | |
| GSE29001 | CD209 | 30835 | 207277_at | 0.0790 | 0.7661 | |
| GSE38129 | CD209 | 30835 | 207277_at | -0.2454 | 0.1093 | |
| GSE45670 | CD209 | 30835 | 207277_at | -0.4462 | 0.0619 | |
| GSE53622 | CD209 | 30835 | 41851 | -0.2308 | 0.0416 | |
| GSE53624 | CD209 | 30835 | 41851 | 0.0847 | 0.3057 | |
| GSE63941 | CD209 | 30835 | 207277_at | -0.0857 | 0.6450 | |
| GSE77861 | CD209 | 30835 | 207278_s_at | -0.1200 | 0.2606 | |
| GSE97050 | CD209 | 30835 | A_24_P186539 | 0.5495 | 0.2713 | |
| SRP007169 | CD209 | 30835 | RNAseq | 1.1887 | 0.0533 | |
| SRP064894 | CD209 | 30835 | RNAseq | 0.6752 | 0.1465 | |
| SRP133303 | CD209 | 30835 | RNAseq | -0.0540 | 0.9051 | |
| SRP159526 | CD209 | 30835 | RNAseq | 0.8273 | 0.2101 | |
| SRP193095 | CD209 | 30835 | RNAseq | 0.3859 | 0.0579 | |
| SRP219564 | CD209 | 30835 | RNAseq | 1.2543 | 0.1320 | |
| TCGA | CD209 | 30835 | RNAseq | -0.1811 | 0.3916 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CD209 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD209:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD209 | 30835 | 4 | 3 | 23 | |
| GSE20123 | CD209 | 30835 | 3 | 2 | 25 | |
| GSE43470 | CD209 | 30835 | 2 | 6 | 35 | |
| GSE46452 | CD209 | 30835 | 47 | 1 | 11 | |
| GSE47630 | CD209 | 30835 | 5 | 7 | 28 | |
| GSE54993 | CD209 | 30835 | 16 | 3 | 51 | |
| GSE54994 | CD209 | 30835 | 6 | 13 | 34 | |
| GSE60625 | CD209 | 30835 | 9 | 0 | 2 | |
| GSE74703 | CD209 | 30835 | 2 | 4 | 30 | |
| GSE74704 | CD209 | 30835 | 0 | 2 | 18 | |
| TCGA | CD209 | 30835 | 9 | 20 | 67 |
Total number of gains: 103; Total number of losses: 61; Total Number of normals: 324.
Somatic mutations of CD209:
Generating mutation plots.
Highly correlated genes for CD209:
Showing top 20/211 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD209 | LILRB5 | 0.676236 | 6 | 0 | 5 |
| CD209 | MPEG1 | 0.675527 | 5 | 0 | 4 |
| CD209 | ZNF423 | 0.672922 | 3 | 0 | 3 |
| CD209 | SLC38A3 | 0.65622 | 3 | 0 | 3 |
| CD209 | FMN1 | 0.652037 | 3 | 0 | 3 |
| CD209 | PLCXD3 | 0.650474 | 4 | 0 | 3 |
| CD209 | DLX6 | 0.641176 | 4 | 0 | 3 |
| CD209 | IDO1 | 0.638539 | 3 | 0 | 3 |
| CD209 | F13A1 | 0.621971 | 9 | 0 | 7 |
| CD209 | FNDC8 | 0.620931 | 4 | 0 | 4 |
| CD209 | NME8 | 0.620914 | 3 | 0 | 3 |
| CD209 | RNASE1 | 0.614307 | 5 | 0 | 4 |
| CD209 | C1QTNF1 | 0.613961 | 4 | 0 | 3 |
| CD209 | TLR4 | 0.608053 | 6 | 0 | 5 |
| CD209 | SLIT3 | 0.60805 | 6 | 0 | 6 |
| CD209 | ATP8B4 | 0.607323 | 7 | 0 | 5 |
| CD209 | VENTX | 0.606664 | 4 | 0 | 3 |
| CD209 | TDRD1 | 0.605503 | 3 | 0 | 3 |
| CD209 | TP53TG5 | 0.60082 | 3 | 0 | 3 |
| CD209 | VSIG4 | 0.600664 | 9 | 0 | 6 |
For details and further investigation, click here
