SLC38A3

 

Full name: solute carrier family 38 member 3 Alias Symbol: G17|SN1
Type: protein-coding gene Cytoband: 3p21.31
Entrez ID: 10991 HGNC ID: HGNC:18044 Ensembl Gene: ENSG00000188338 OMIM ID: 604437
Drug and gene relationship at DGIdb

 

Expression of SLC38A3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SLC38A3 10991 205972_at -0.1113 0.5406
GSE20347 SLC38A3 10991 205972_at -0.1459 0.0599
GSE23400 SLC38A3 10991 205972_at -0.1141 0.0050
GSE26886 SLC38A3 10991 205972_at 0.2292 0.0855
GSE29001 SLC38A3 10991 205972_at -0.1758 0.3237
GSE38129 SLC38A3 10991 205972_at -0.1926 0.0228
GSE45670 SLC38A3 10991 205972_at -0.0550 0.6558
GSE53622 SLC38A3 10991 18092 0.6750 0.0000
GSE53624 SLC38A3 10991 18092 0.5300 0.0000
GSE63941 SLC38A3 10991 205972_at 0.2642 0.2581
GSE77861 SLC38A3 10991 205972_at -0.1669 0.4084
SRP007169 SLC38A3 10991 RNAseq -6.6902 0.0000
SRP159526 SLC38A3 10991 RNAseq 0.5240 0.6076
TCGA SLC38A3 10991 RNAseq -1.5652 0.0025

Upregulated datasets: 0; Downregulated datasets: 2.  

 

Survival by SLC38A3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SLC38A3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SLC38A3 10991 0 18 12
GSE20123 SLC38A3 10991 0 19 11
GSE43470 SLC38A3 10991 0 19 24
GSE46452 SLC38A3 10991 2 16 41
GSE47630 SLC38A3 10991 1 24 15
GSE54993 SLC38A3 10991 6 2 62
GSE54994 SLC38A3 10991 1 33 19
GSE60625 SLC38A3 10991 5 0 6
GSE74703 SLC38A3 10991 0 15 21
GSE74704 SLC38A3 10991 0 12 8
TCGA SLC38A3 10991 0 78 18

Total number of gains: 15; Total number of losses: 236; Total Number of normals: 237.  

 

Somatic mutations of SLC38A3:

 

Generating mutation plots.

 

Highly correlated genes for SLC38A3:

 

Showing top 20/866 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SLC38A3SSC5D0.706247303
SLC38A3OSBP20.694584404
SLC38A3MAPK8IP30.690819303
SLC38A3ACY10.68518303
SLC38A3SELPLG0.677549303
SLC38A3VWA70.675778707
SLC38A3ZMAT40.671358403
SLC38A3WAS0.671099303
SLC38A3FHL30.669437303
SLC38A3KLHL310.666207303
SLC38A3OR2H20.66452706
SLC38A3FABP20.663365504
SLC38A3TMEM59L0.66229808
SLC38A3SLC1A70.658096404
SLC38A3IBA570.656945505
SLC38A3CD2090.65622303
SLC38A3ZNF4440.654947303
SLC38A3MYBPC30.652885808
SLC38A3PPP1R3F0.652765303
SLC38A3RARG0.652513404

For details and further investigation, click here