| Full name: coagulation factor XIII A chain | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p25.1 | ||
| Entrez ID: 2162 | HGNC ID: HGNC:3531 | Ensembl Gene: ENSG00000124491 | OMIM ID: 134570 |
| Drug and gene relationship at DGIdb | |||
F13A1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04610 | Complement and coagulation cascades |
Expression of F13A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | F13A1 | 2162 | 203305_at | -1.7328 | 0.2689 | |
| GSE20347 | F13A1 | 2162 | 203305_at | -0.0531 | 0.8163 | |
| GSE23400 | F13A1 | 2162 | 203305_at | -0.0909 | 0.5403 | |
| GSE26886 | F13A1 | 2162 | 203305_at | -0.1017 | 0.8359 | |
| GSE29001 | F13A1 | 2162 | 203305_at | 0.0644 | 0.8071 | |
| GSE38129 | F13A1 | 2162 | 203305_at | -0.4244 | 0.2203 | |
| GSE45670 | F13A1 | 2162 | 203305_at | -2.2155 | 0.0001 | |
| GSE53622 | F13A1 | 2162 | 7791 | -1.4140 | 0.0000 | |
| GSE53624 | F13A1 | 2162 | 98401 | -0.9939 | 0.0000 | |
| GSE63941 | F13A1 | 2162 | 203305_at | 0.1047 | 0.5558 | |
| GSE77861 | F13A1 | 2162 | 203305_at | 0.1910 | 0.4024 | |
| GSE97050 | F13A1 | 2162 | A_33_P3416097 | 0.1760 | 0.7898 | |
| SRP007169 | F13A1 | 2162 | RNAseq | 0.9860 | 0.0455 | |
| SRP008496 | F13A1 | 2162 | RNAseq | 1.9691 | 0.0000 | |
| SRP064894 | F13A1 | 2162 | RNAseq | -0.0089 | 0.9840 | |
| SRP133303 | F13A1 | 2162 | RNAseq | -1.1222 | 0.0028 | |
| SRP159526 | F13A1 | 2162 | RNAseq | 0.6184 | 0.3019 | |
| SRP193095 | F13A1 | 2162 | RNAseq | -0.1269 | 0.7598 | |
| SRP219564 | F13A1 | 2162 | RNAseq | 0.8052 | 0.4645 | |
| TCGA | F13A1 | 2162 | RNAseq | -0.5308 | 0.0149 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by F13A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of F13A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | F13A1 | 2162 | 3 | 6 | 21 | |
| GSE20123 | F13A1 | 2162 | 3 | 6 | 21 | |
| GSE43470 | F13A1 | 2162 | 8 | 2 | 33 | |
| GSE46452 | F13A1 | 2162 | 1 | 10 | 48 | |
| GSE47630 | F13A1 | 2162 | 7 | 8 | 25 | |
| GSE54993 | F13A1 | 2162 | 1 | 1 | 68 | |
| GSE54994 | F13A1 | 2162 | 10 | 3 | 40 | |
| GSE60625 | F13A1 | 2162 | 0 | 1 | 10 | |
| GSE74703 | F13A1 | 2162 | 7 | 2 | 27 | |
| GSE74704 | F13A1 | 2162 | 2 | 2 | 16 | |
| TCGA | F13A1 | 2162 | 15 | 29 | 52 |
Total number of gains: 57; Total number of losses: 70; Total Number of normals: 361.
Somatic mutations of F13A1:
Generating mutation plots.
Highly correlated genes for F13A1:
Showing top 20/612 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| F13A1 | TPP1 | 0.802453 | 3 | 0 | 3 |
| F13A1 | GIMAP5 | 0.768677 | 3 | 0 | 3 |
| F13A1 | CCDC80 | 0.767967 | 6 | 0 | 6 |
| F13A1 | RNF14 | 0.737624 | 3 | 0 | 3 |
| F13A1 | C3 | 0.735789 | 8 | 0 | 7 |
| F13A1 | LYVE1 | 0.719425 | 10 | 0 | 9 |
| F13A1 | DAB2 | 0.71479 | 9 | 0 | 8 |
| F13A1 | AP2B1 | 0.706153 | 3 | 0 | 3 |
| F13A1 | TFPI | 0.699896 | 8 | 0 | 7 |
| F13A1 | ECSCR | 0.699418 | 6 | 0 | 6 |
| F13A1 | MMRN1 | 0.699328 | 9 | 0 | 8 |
| F13A1 | TRIM8 | 0.696653 | 3 | 0 | 3 |
| F13A1 | CMA1 | 0.694804 | 8 | 0 | 6 |
| F13A1 | COLEC12 | 0.69456 | 11 | 0 | 10 |
| F13A1 | RNASE1 | 0.688286 | 10 | 0 | 7 |
| F13A1 | TNFSF12 | 0.68688 | 4 | 0 | 4 |
| F13A1 | P2RY12 | 0.685834 | 5 | 0 | 5 |
| F13A1 | FZD1 | 0.685565 | 3 | 0 | 3 |
| F13A1 | TEK | 0.679319 | 6 | 0 | 5 |
| F13A1 | AP3M1 | 0.678897 | 3 | 0 | 3 |
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