ATP8B4

 

Full name: ATPase phospholipid transporting 8B4 (putative) Alias Symbol: ATPIM|KIAA1939
Type: protein-coding gene Cytoband: 15q21.2
Entrez ID: 79895 HGNC ID: HGNC:13536 Ensembl Gene: ENSG00000104043 OMIM ID: 609123
Drug and gene relationship at DGIdb

 

Expression of ATP8B4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ATP8B4 79895 220416_at -0.1725 0.8170
GSE20347 ATP8B4 79895 220416_at 0.0050 0.9408
GSE23400 ATP8B4 79895 220416_at 0.0130 0.7267
GSE26886 ATP8B4 79895 220416_at -0.0226 0.9171
GSE29001 ATP8B4 79895 220416_at 0.1565 0.2600
GSE38129 ATP8B4 79895 220416_at -0.1066 0.3947
GSE45670 ATP8B4 79895 220416_at -0.5278 0.0083
GSE53622 ATP8B4 79895 112325 -0.5031 0.0003
GSE53624 ATP8B4 79895 83537 -0.3966 0.0126
GSE63941 ATP8B4 79895 220416_at -5.6757 0.0000
GSE77861 ATP8B4 79895 220416_at -0.0064 0.9489
GSE97050 ATP8B4 79895 A_23_P163216 0.2716 0.3688
SRP007169 ATP8B4 79895 RNAseq 0.1917 0.7283
SRP008496 ATP8B4 79895 RNAseq 0.4124 0.2655
SRP064894 ATP8B4 79895 RNAseq 0.4163 0.2102
SRP133303 ATP8B4 79895 RNAseq -0.1214 0.7214
SRP159526 ATP8B4 79895 RNAseq 0.0976 0.7970
SRP193095 ATP8B4 79895 RNAseq -0.1927 0.2939
SRP219564 ATP8B4 79895 RNAseq 0.3369 0.5256
TCGA ATP8B4 79895 RNAseq 0.0272 0.8968

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by ATP8B4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ATP8B4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ATP8B4 79895 5 3 22
GSE20123 ATP8B4 79895 5 3 22
GSE43470 ATP8B4 79895 5 4 34
GSE46452 ATP8B4 79895 3 7 49
GSE47630 ATP8B4 79895 8 10 22
GSE54993 ATP8B4 79895 4 6 60
GSE54994 ATP8B4 79895 5 7 41
GSE60625 ATP8B4 79895 4 0 7
GSE74703 ATP8B4 79895 5 3 28
GSE74704 ATP8B4 79895 2 3 15
TCGA ATP8B4 79895 9 16 71

Total number of gains: 55; Total number of losses: 62; Total Number of normals: 371.  


 

Somatic mutations of ATP8B4:

 

Generating mutation plots.

 

Highly correlated genes for ATP8B4:

 

Showing top 20/523 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ATP8B4MPEG10.787693605
ATP8B4GPR340.770611505
ATP8B4GIMAP50.766228303
ATP8B4C1orf1620.741935606
ATP8B4GIMAP10.728492605
ATP8B4SLC14A10.716691303
ATP8B4CR10.713756504
ATP8B4ZNF5820.711064303
ATP8B4THEMIS0.701071303
ATP8B4PDE7B0.687689606
ATP8B4GAB30.686391605
ATP8B4TNFSF80.683682504
ATP8B4ARHGEF60.682023908
ATP8B4LINC009680.679054404
ATP8B4KIAA12110.678559303
ATP8B4GIMAP20.670214605
ATP8B4TMEM176B0.670206908
ATP8B4CMKLR10.668769806
ATP8B4ZNF5210.667522403
ATP8B4PLCL20.665288807

For details and further investigation, click here