| Full name: CD34 molecule | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q32.2 | ||
| Entrez ID: 947 | HGNC ID: HGNC:1662 | Ensembl Gene: ENSG00000174059 | OMIM ID: 142230 |
| Drug and gene relationship at DGIdb | |||
Expression of CD34:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD34 | 947 | 209543_s_at | -0.3899 | 0.5104 | |
| GSE20347 | CD34 | 947 | 209543_s_at | 0.0169 | 0.8965 | |
| GSE23400 | CD34 | 947 | 209543_s_at | -0.3370 | 0.0002 | |
| GSE26886 | CD34 | 947 | 209543_s_at | -0.3021 | 0.0861 | |
| GSE29001 | CD34 | 947 | 209543_s_at | -0.1076 | 0.6066 | |
| GSE38129 | CD34 | 947 | 209543_s_at | -0.4906 | 0.0430 | |
| GSE45670 | CD34 | 947 | 209543_s_at | -0.3229 | 0.0022 | |
| GSE53622 | CD34 | 947 | 26497 | -0.8929 | 0.0000 | |
| GSE53624 | CD34 | 947 | 26497 | -1.0444 | 0.0000 | |
| GSE63941 | CD34 | 947 | 209543_s_at | -0.1332 | 0.3638 | |
| GSE77861 | CD34 | 947 | 209543_s_at | 0.0155 | 0.9332 | |
| GSE97050 | CD34 | 947 | A_33_P3225046 | -0.4553 | 0.2281 | |
| SRP007169 | CD34 | 947 | RNAseq | 0.1079 | 0.7860 | |
| SRP008496 | CD34 | 947 | RNAseq | 0.5147 | 0.1766 | |
| SRP064894 | CD34 | 947 | RNAseq | 0.3024 | 0.4413 | |
| SRP133303 | CD34 | 947 | RNAseq | -0.9916 | 0.0024 | |
| SRP159526 | CD34 | 947 | RNAseq | -0.6871 | 0.1437 | |
| SRP193095 | CD34 | 947 | RNAseq | 0.3030 | 0.1247 | |
| SRP219564 | CD34 | 947 | RNAseq | 0.1860 | 0.8339 | |
| TCGA | CD34 | 947 | RNAseq | -0.4138 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CD34 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD34:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD34 | 947 | 11 | 0 | 19 | |
| GSE20123 | CD34 | 947 | 11 | 0 | 19 | |
| GSE43470 | CD34 | 947 | 9 | 0 | 34 | |
| GSE46452 | CD34 | 947 | 3 | 1 | 55 | |
| GSE47630 | CD34 | 947 | 14 | 0 | 26 | |
| GSE54993 | CD34 | 947 | 0 | 6 | 64 | |
| GSE54994 | CD34 | 947 | 14 | 0 | 39 | |
| GSE60625 | CD34 | 947 | 0 | 0 | 11 | |
| GSE74703 | CD34 | 947 | 9 | 0 | 27 | |
| GSE74704 | CD34 | 947 | 5 | 0 | 15 | |
| TCGA | CD34 | 947 | 45 | 3 | 48 |
Total number of gains: 121; Total number of losses: 10; Total Number of normals: 357.
Somatic mutations of CD34:
Generating mutation plots.
Highly correlated genes for CD34:
Showing top 20/1180 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD34 | SLIT2 | 0.800236 | 6 | 0 | 6 |
| CD34 | KAT7 | 0.794684 | 3 | 0 | 3 |
| CD34 | CYP2U1 | 0.792819 | 4 | 0 | 4 |
| CD34 | CLEC3B | 0.792426 | 3 | 0 | 3 |
| CD34 | RNASE4 | 0.789617 | 5 | 0 | 5 |
| CD34 | STARD13 | 0.786622 | 6 | 0 | 6 |
| CD34 | SORCS1 | 0.785537 | 4 | 0 | 4 |
| CD34 | SLC16A4 | 0.774761 | 6 | 0 | 6 |
| CD34 | LAMA2 | 0.77265 | 5 | 0 | 5 |
| CD34 | ARHGAP6 | 0.769311 | 7 | 0 | 6 |
| CD34 | CYS1 | 0.769083 | 4 | 0 | 4 |
| CD34 | RRAS | 0.758619 | 5 | 0 | 5 |
| CD34 | BTN1A1 | 0.755752 | 3 | 0 | 3 |
| CD34 | FBXO30 | 0.755368 | 3 | 0 | 3 |
| CD34 | CHRDL1 | 0.752756 | 7 | 0 | 7 |
| CD34 | LRRC4C | 0.751405 | 3 | 0 | 3 |
| CD34 | XKR4 | 0.74903 | 5 | 0 | 5 |
| CD34 | LRCH2 | 0.747711 | 4 | 0 | 4 |
| CD34 | LMO3 | 0.745134 | 7 | 0 | 7 |
| CD34 | PI16 | 0.744082 | 5 | 0 | 5 |
For details and further investigation, click here
