| Full name: LIM domain only 3 | Alias Symbol: Rhom-3|DAT1 | ||
| Type: protein-coding gene | Cytoband: 12p12.3 | ||
| Entrez ID: 55885 | HGNC ID: HGNC:6643 | Ensembl Gene: ENSG00000048540 | OMIM ID: 180386 |
| Drug and gene relationship at DGIdb | |||
Expression of LMO3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LMO3 | 55885 | 204424_s_at | -1.6432 | 0.2617 | |
| GSE20347 | LMO3 | 55885 | 204424_s_at | -0.1003 | 0.6894 | |
| GSE23400 | LMO3 | 55885 | 204424_s_at | -0.3340 | 0.0081 | |
| GSE26886 | LMO3 | 55885 | 204424_s_at | 0.4135 | 0.0523 | |
| GSE29001 | LMO3 | 55885 | 204424_s_at | -0.2994 | 0.6109 | |
| GSE38129 | LMO3 | 55885 | 204424_s_at | -1.0629 | 0.0306 | |
| GSE45670 | LMO3 | 55885 | 204424_s_at | -2.3917 | 0.0000 | |
| GSE53622 | LMO3 | 55885 | 43242 | -0.5720 | 0.0069 | |
| GSE53624 | LMO3 | 55885 | 43242 | -0.3624 | 0.0096 | |
| GSE63941 | LMO3 | 55885 | 204424_s_at | -0.4499 | 0.1996 | |
| GSE77861 | LMO3 | 55885 | 204424_s_at | 0.0187 | 0.8715 | |
| GSE97050 | LMO3 | 55885 | A_24_P381441 | -1.6726 | 0.1236 | |
| SRP064894 | LMO3 | 55885 | RNAseq | 0.7204 | 0.2141 | |
| SRP133303 | LMO3 | 55885 | RNAseq | 1.1370 | 0.1676 | |
| SRP159526 | LMO3 | 55885 | RNAseq | 0.6372 | 0.2940 | |
| SRP219564 | LMO3 | 55885 | RNAseq | -1.2445 | 0.3541 | |
| TCGA | LMO3 | 55885 | RNAseq | -1.3669 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by LMO3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LMO3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LMO3 | 55885 | 8 | 2 | 20 | |
| GSE20123 | LMO3 | 55885 | 8 | 2 | 20 | |
| GSE43470 | LMO3 | 55885 | 8 | 3 | 32 | |
| GSE46452 | LMO3 | 55885 | 10 | 1 | 48 | |
| GSE47630 | LMO3 | 55885 | 14 | 1 | 25 | |
| GSE54993 | LMO3 | 55885 | 1 | 9 | 60 | |
| GSE54994 | LMO3 | 55885 | 11 | 2 | 40 | |
| GSE60625 | LMO3 | 55885 | 0 | 1 | 10 | |
| GSE74703 | LMO3 | 55885 | 8 | 2 | 26 | |
| GSE74704 | LMO3 | 55885 | 6 | 1 | 13 | |
| TCGA | LMO3 | 55885 | 41 | 5 | 50 |
Total number of gains: 115; Total number of losses: 29; Total Number of normals: 344.
Somatic mutations of LMO3:
Generating mutation plots.
Highly correlated genes for LMO3:
Showing top 20/1099 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LMO3 | RNASE4 | 0.790424 | 5 | 0 | 5 |
| LMO3 | CCDC136 | 0.787655 | 4 | 0 | 4 |
| LMO3 | SLIT2 | 0.778707 | 9 | 0 | 8 |
| LMO3 | SYNC | 0.777591 | 6 | 0 | 6 |
| LMO3 | FNDC5 | 0.767239 | 4 | 0 | 4 |
| LMO3 | MYOC | 0.765919 | 9 | 0 | 8 |
| LMO3 | NEGR1 | 0.765828 | 5 | 0 | 5 |
| LMO3 | XKR4 | 0.764442 | 5 | 0 | 4 |
| LMO3 | NFASC | 0.760982 | 5 | 0 | 5 |
| LMO3 | NOVA1 | 0.760693 | 7 | 0 | 6 |
| LMO3 | SORCS1 | 0.750814 | 4 | 0 | 4 |
| LMO3 | PRKAR2B | 0.74937 | 9 | 0 | 8 |
| LMO3 | FBXO30 | 0.749155 | 4 | 0 | 4 |
| LMO3 | CYS1 | 0.748129 | 6 | 0 | 5 |
| LMO3 | CASQ2 | 0.746096 | 11 | 0 | 10 |
| LMO3 | CD34 | 0.745134 | 7 | 0 | 7 |
| LMO3 | ST6GAL2 | 0.744954 | 3 | 0 | 3 |
| LMO3 | MEOX2 | 0.744212 | 10 | 0 | 9 |
| LMO3 | MYOT | 0.741139 | 10 | 0 | 10 |
| LMO3 | FRY | 0.740104 | 8 | 0 | 8 |
For details and further investigation, click here
