| Full name: leucine rich repeat containing 4C | Alias Symbol: KIAA1580|NGL-1 | ||
| Type: protein-coding gene | Cytoband: 11p12 | ||
| Entrez ID: 57689 | HGNC ID: HGNC:29317 | Ensembl Gene: ENSG00000148948 | OMIM ID: 608817 |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC4C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC4C | 57689 | 232226_at | -0.4486 | 0.4570 | |
| GSE26886 | LRRC4C | 57689 | 232226_at | 0.2896 | 0.3328 | |
| GSE45670 | LRRC4C | 57689 | 232226_at | -0.2439 | 0.0154 | |
| GSE53622 | LRRC4C | 57689 | 58340 | -0.8132 | 0.0000 | |
| GSE53624 | LRRC4C | 57689 | 58340 | -0.8746 | 0.0000 | |
| GSE63941 | LRRC4C | 57689 | 232226_at | 0.4087 | 0.0067 | |
| GSE77861 | LRRC4C | 57689 | 232226_at | 0.0069 | 0.9621 | |
| SRP133303 | LRRC4C | 57689 | RNAseq | -0.1543 | 0.8326 | |
| TCGA | LRRC4C | 57689 | RNAseq | -1.3365 | 0.0166 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LRRC4C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC4C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC4C | 57689 | 3 | 7 | 20 | |
| GSE20123 | LRRC4C | 57689 | 2 | 7 | 21 | |
| GSE43470 | LRRC4C | 57689 | 4 | 6 | 33 | |
| GSE46452 | LRRC4C | 57689 | 8 | 5 | 46 | |
| GSE47630 | LRRC4C | 57689 | 3 | 10 | 27 | |
| GSE54993 | LRRC4C | 57689 | 3 | 1 | 66 | |
| GSE54994 | LRRC4C | 57689 | 3 | 10 | 40 | |
| GSE60625 | LRRC4C | 57689 | 0 | 0 | 11 | |
| GSE74703 | LRRC4C | 57689 | 3 | 4 | 29 | |
| GSE74704 | LRRC4C | 57689 | 1 | 6 | 13 | |
| TCGA | LRRC4C | 57689 | 13 | 24 | 59 |
Total number of gains: 43; Total number of losses: 80; Total Number of normals: 365.
Somatic mutations of LRRC4C:
Generating mutation plots.
Highly correlated genes for LRRC4C:
Showing top 20/197 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC4C | SORCS1 | 0.782427 | 3 | 0 | 3 |
| LRRC4C | CD34 | 0.751405 | 3 | 0 | 3 |
| LRRC4C | PLP1 | 0.731495 | 3 | 0 | 3 |
| LRRC4C | PGR | 0.723484 | 5 | 0 | 5 |
| LRRC4C | ADAMTSL3 | 0.716122 | 3 | 0 | 3 |
| LRRC4C | SH3GL2 | 0.705377 | 4 | 0 | 4 |
| LRRC4C | SLIT2 | 0.70028 | 4 | 0 | 4 |
| LRRC4C | ABRA | 0.699666 | 3 | 0 | 3 |
| LRRC4C | FRRS1L | 0.699139 | 4 | 0 | 4 |
| LRRC4C | MYOT | 0.690821 | 4 | 0 | 4 |
| LRRC4C | ACACB | 0.690708 | 3 | 0 | 3 |
| LRRC4C | CYSLTR1 | 0.687864 | 4 | 0 | 4 |
| LRRC4C | LRRTM1 | 0.682466 | 5 | 0 | 4 |
| LRRC4C | ACBD4 | 0.681831 | 3 | 0 | 3 |
| LRRC4C | C1QTNF7 | 0.681269 | 4 | 0 | 4 |
| LRRC4C | PRR26 | 0.679797 | 4 | 0 | 3 |
| LRRC4C | LMO3 | 0.677362 | 4 | 0 | 4 |
| LRRC4C | NPY1R | 0.671257 | 3 | 0 | 3 |
| LRRC4C | XKR4 | 0.670978 | 4 | 0 | 4 |
| LRRC4C | PLIN4 | 0.66808 | 4 | 0 | 3 |
For details and further investigation, click here
