| Full name: CD47 molecule | Alias Symbol: IAP|OA3 | ||
| Type: protein-coding gene | Cytoband: 3q13.12 | ||
| Entrez ID: 961 | HGNC ID: HGNC:1682 | Ensembl Gene: ENSG00000196776 | OMIM ID: 601028 |
| Drug and gene relationship at DGIdb | |||
Expression of CD47:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD47 | 961 | 213857_s_at | 0.3034 | 0.7350 | |
| GSE20347 | CD47 | 961 | 213857_s_at | -0.0952 | 0.7138 | |
| GSE23400 | CD47 | 961 | 211075_s_at | 0.4224 | 0.0041 | |
| GSE26886 | CD47 | 961 | 213857_s_at | -0.3485 | 0.1754 | |
| GSE29001 | CD47 | 961 | 213857_s_at | 0.0738 | 0.7934 | |
| GSE38129 | CD47 | 961 | 213857_s_at | 0.0330 | 0.8975 | |
| GSE45670 | CD47 | 961 | 213857_s_at | 0.7769 | 0.0001 | |
| GSE53622 | CD47 | 961 | 46693 | 0.0830 | 0.3182 | |
| GSE53624 | CD47 | 961 | 46693 | -0.0370 | 0.7446 | |
| GSE63941 | CD47 | 961 | 211075_s_at | 0.2621 | 0.7522 | |
| GSE77861 | CD47 | 961 | 213857_s_at | -0.2162 | 0.5021 | |
| GSE97050 | CD47 | 961 | A_23_P6935 | 0.2773 | 0.3326 | |
| SRP007169 | CD47 | 961 | RNAseq | -0.7285 | 0.0737 | |
| SRP008496 | CD47 | 961 | RNAseq | 0.0179 | 0.9624 | |
| SRP064894 | CD47 | 961 | RNAseq | 0.3679 | 0.0219 | |
| SRP133303 | CD47 | 961 | RNAseq | 0.0230 | 0.9192 | |
| SRP159526 | CD47 | 961 | RNAseq | -0.3210 | 0.3359 | |
| SRP193095 | CD47 | 961 | RNAseq | 0.0959 | 0.5242 | |
| SRP219564 | CD47 | 961 | RNAseq | 0.0828 | 0.8018 | |
| TCGA | CD47 | 961 | RNAseq | -0.0154 | 0.8078 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CD47 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD47:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD47 | 961 | 18 | 1 | 11 | |
| GSE20123 | CD47 | 961 | 17 | 1 | 12 | |
| GSE43470 | CD47 | 961 | 18 | 1 | 24 | |
| GSE46452 | CD47 | 961 | 12 | 6 | 41 | |
| GSE47630 | CD47 | 961 | 16 | 6 | 18 | |
| GSE54993 | CD47 | 961 | 2 | 5 | 63 | |
| GSE54994 | CD47 | 961 | 28 | 5 | 20 | |
| GSE60625 | CD47 | 961 | 0 | 6 | 5 | |
| GSE74703 | CD47 | 961 | 15 | 1 | 20 | |
| GSE74704 | CD47 | 961 | 14 | 1 | 5 | |
| TCGA | CD47 | 961 | 50 | 8 | 38 |
Total number of gains: 190; Total number of losses: 41; Total Number of normals: 257.
Somatic mutations of CD47:
Generating mutation plots.
Highly correlated genes for CD47:
Showing top 20/399 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD47 | COMMD9 | 0.792331 | 3 | 0 | 3 |
| CD47 | EIF3M | 0.786104 | 3 | 0 | 3 |
| CD47 | NUP88 | 0.775392 | 3 | 0 | 3 |
| CD47 | CCNH | 0.76147 | 3 | 0 | 3 |
| CD47 | TTC4 | 0.753197 | 3 | 0 | 3 |
| CD47 | GUK1 | 0.740912 | 3 | 0 | 3 |
| CD47 | IFI27L2 | 0.736979 | 3 | 0 | 3 |
| CD47 | PARP14 | 0.731542 | 3 | 0 | 3 |
| CD47 | TRIM47 | 0.723434 | 3 | 0 | 3 |
| CD47 | GGCX | 0.718051 | 4 | 0 | 4 |
| CD47 | NIT1 | 0.716117 | 3 | 0 | 3 |
| CD47 | ALDH7A1 | 0.713094 | 4 | 0 | 3 |
| CD47 | EID2 | 0.711814 | 3 | 0 | 3 |
| CD47 | ZW10 | 0.710503 | 3 | 0 | 3 |
| CD47 | TMEM92 | 0.708885 | 3 | 0 | 3 |
| CD47 | SGMS1 | 0.708841 | 3 | 0 | 3 |
| CD47 | DDX55 | 0.698065 | 3 | 0 | 3 |
| CD47 | DDOST | 0.693852 | 4 | 0 | 4 |
| CD47 | STON2 | 0.69286 | 4 | 0 | 3 |
| CD47 | TMEM167A | 0.68904 | 4 | 0 | 3 |
For details and further investigation, click here
