| Full name: poly(ADP-ribose) polymerase family member 14 | Alias Symbol: KIAA1268|pART8 | ||
| Type: protein-coding gene | Cytoband: 3q21.1 | ||
| Entrez ID: 54625 | HGNC ID: HGNC:29232 | Ensembl Gene: ENSG00000173193 | OMIM ID: 610028 |
| Drug and gene relationship at DGIdb | |||
Expression of PARP14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PARP14 | 54625 | 224701_at | 1.0305 | 0.1185 | |
| GSE26886 | PARP14 | 54625 | 224701_at | 0.5622 | 0.0614 | |
| GSE45670 | PARP14 | 54625 | 224701_at | 1.6188 | 0.0000 | |
| GSE53622 | PARP14 | 54625 | 104852 | 1.1428 | 0.0000 | |
| GSE53624 | PARP14 | 54625 | 25892 | 1.0731 | 0.0000 | |
| GSE63941 | PARP14 | 54625 | 224701_at | 0.0127 | 0.9877 | |
| GSE77861 | PARP14 | 54625 | 224701_at | 0.7249 | 0.0392 | |
| GSE97050 | PARP14 | 54625 | A_24_P161018 | 0.9908 | 0.0826 | |
| SRP007169 | PARP14 | 54625 | RNAseq | 2.9926 | 0.0000 | |
| SRP008496 | PARP14 | 54625 | RNAseq | 2.5722 | 0.0000 | |
| SRP064894 | PARP14 | 54625 | RNAseq | 1.6107 | 0.0000 | |
| SRP133303 | PARP14 | 54625 | RNAseq | 1.1902 | 0.0000 | |
| SRP159526 | PARP14 | 54625 | RNAseq | -0.0988 | 0.7970 | |
| SRP193095 | PARP14 | 54625 | RNAseq | 1.2042 | 0.0000 | |
| SRP219564 | PARP14 | 54625 | RNAseq | 0.9514 | 0.0632 | |
| TCGA | PARP14 | 54625 | RNAseq | 0.2938 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by PARP14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PARP14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PARP14 | 54625 | 18 | 0 | 12 | |
| GSE20123 | PARP14 | 54625 | 18 | 0 | 12 | |
| GSE43470 | PARP14 | 54625 | 20 | 0 | 23 | |
| GSE46452 | PARP14 | 54625 | 14 | 5 | 40 | |
| GSE47630 | PARP14 | 54625 | 17 | 4 | 19 | |
| GSE54993 | PARP14 | 54625 | 2 | 6 | 62 | |
| GSE54994 | PARP14 | 54625 | 30 | 4 | 19 | |
| GSE60625 | PARP14 | 54625 | 0 | 6 | 5 | |
| GSE74703 | PARP14 | 54625 | 16 | 0 | 20 | |
| GSE74704 | PARP14 | 54625 | 13 | 0 | 7 | |
| TCGA | PARP14 | 54625 | 54 | 6 | 36 |
Total number of gains: 202; Total number of losses: 31; Total Number of normals: 255.
Somatic mutations of PARP14:
Generating mutation plots.
Highly correlated genes for PARP14:
Showing top 20/1277 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PARP14 | USP41 | 0.821748 | 3 | 0 | 3 |
| PARP14 | C6orf62 | 0.814867 | 3 | 0 | 3 |
| PARP14 | DTX3L | 0.809278 | 9 | 0 | 8 |
| PARP14 | ARMC8 | 0.800046 | 3 | 0 | 3 |
| PARP14 | CD80 | 0.793631 | 3 | 0 | 3 |
| PARP14 | STAT1 | 0.784421 | 8 | 0 | 8 |
| PARP14 | PARP12 | 0.774063 | 9 | 0 | 9 |
| PARP14 | ATP2C1 | 0.766442 | 6 | 0 | 6 |
| PARP14 | PARP9 | 0.765216 | 9 | 0 | 9 |
| PARP14 | TAP1 | 0.765051 | 7 | 0 | 6 |
| PARP14 | ZNF284 | 0.764477 | 3 | 0 | 3 |
| PARP14 | MBD4 | 0.760036 | 6 | 0 | 6 |
| PARP14 | DDX60 | 0.75476 | 9 | 0 | 9 |
| PARP14 | FRMD8 | 0.750402 | 3 | 0 | 3 |
| PARP14 | UBE2L6 | 0.749675 | 9 | 0 | 8 |
| PARP14 | USP18 | 0.746894 | 9 | 0 | 9 |
| PARP14 | IFI44 | 0.733982 | 9 | 0 | 8 |
| PARP14 | IFI35 | 0.732863 | 9 | 0 | 9 |
| PARP14 | LSR | 0.732067 | 3 | 0 | 3 |
| PARP14 | CD47 | 0.731542 | 3 | 0 | 3 |
For details and further investigation, click here
