NUP88

 

Full name: nucleoporin 88 Alias Symbol: MGC8530
Type: protein-coding gene Cytoband: 17p13.2
Entrez ID: 4927 HGNC ID: HGNC:8067 Ensembl Gene: ENSG00000108559 OMIM ID: 602552
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of NUP88:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NUP88 4927 202900_s_at 0.2608 0.4860
GSE20347 NUP88 4927 202900_s_at 0.2973 0.1615
GSE23400 NUP88 4927 214192_at -0.3108 0.0000
GSE26886 NUP88 4927 202900_s_at 0.8120 0.0006
GSE29001 NUP88 4927 202900_s_at 0.4539 0.1539
GSE38129 NUP88 4927 202900_s_at 0.4601 0.0011
GSE45670 NUP88 4927 202900_s_at 0.3767 0.0429
GSE53622 NUP88 4927 5362 0.5777 0.0000
GSE53624 NUP88 4927 5362 0.5104 0.0000
GSE63941 NUP88 4927 202900_s_at 0.7292 0.0831
GSE77861 NUP88 4927 202900_s_at 0.6763 0.0274
GSE97050 NUP88 4927 A_23_P152919 0.4029 0.2017
SRP007169 NUP88 4927 RNAseq 0.3246 0.3458
SRP008496 NUP88 4927 RNAseq 0.2335 0.2878
SRP064894 NUP88 4927 RNAseq 0.3654 0.0297
SRP133303 NUP88 4927 RNAseq 0.0698 0.5019
SRP159526 NUP88 4927 RNAseq 0.4273 0.0450
SRP193095 NUP88 4927 RNAseq 0.1082 0.3235
SRP219564 NUP88 4927 RNAseq 0.0592 0.7989
TCGA NUP88 4927 RNAseq 0.0680 0.1761

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by NUP88 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NUP88:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NUP88 4927 5 2 23
GSE20123 NUP88 4927 5 3 22
GSE43470 NUP88 4927 1 6 36
GSE46452 NUP88 4927 34 1 24
GSE47630 NUP88 4927 7 1 32
GSE54993 NUP88 4927 4 3 63
GSE54994 NUP88 4927 5 8 40
GSE60625 NUP88 4927 4 0 7
GSE74703 NUP88 4927 1 3 32
GSE74704 NUP88 4927 3 1 16
TCGA NUP88 4927 18 20 58

Total number of gains: 87; Total number of losses: 48; Total Number of normals: 353.  

 

Somatic mutations of NUP88:

 

Generating mutation plots.

 

Highly correlated genes for NUP88:

 

Showing top 20/605 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NUP88CD470.775392303
NUP88PET1170.76449404
NUP88ANAPC10.751841303
NUP88ERVW-10.735325303
NUP88ALKBH60.734889404
NUP88MRPL110.73302303
NUP88C18orf540.722465403
NUP88ACY10.720221303
NUP88PMS20.715715303
NUP88PYCR20.715304303
NUP88SCNM10.712238303
NUP88PTCD10.710844303
NUP88ANAPC40.705091303
NUP88APH1B0.703602303
NUP88PPIL10.703406505
NUP88EBNA1BP20.702869303
NUP88TYW50.699428404
NUP88ANKRD110.697427403
NUP88ZNF5070.696499303
NUP88LARP10.695752403

For details and further investigation, click here