| Full name: interferon alpha inducible protein 27 like 2 | Alias Symbol: TLH29 | ||
| Type: protein-coding gene | Cytoband: 14q32.12 | ||
| Entrez ID: 83982 | HGNC ID: HGNC:19753 | Ensembl Gene: ENSG00000119632 | OMIM ID: 611319 |
| Drug and gene relationship at DGIdb | |||
Expression of IFI27L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFI27L2 | 83982 | 223626_x_at | 0.0130 | 0.9813 | |
| GSE26886 | IFI27L2 | 83982 | 223626_x_at | 0.6215 | 0.0006 | |
| GSE45670 | IFI27L2 | 83982 | 223626_x_at | 0.2323 | 0.0577 | |
| GSE53622 | IFI27L2 | 83982 | 44013 | 0.3616 | 0.0000 | |
| GSE53624 | IFI27L2 | 83982 | 44013 | 0.6429 | 0.0000 | |
| GSE63941 | IFI27L2 | 83982 | 223626_x_at | -1.1130 | 0.0614 | |
| GSE77861 | IFI27L2 | 83982 | 223626_x_at | 0.0827 | 0.8029 | |
| GSE97050 | IFI27L2 | 83982 | A_23_P140146 | 0.2837 | 0.2630 | |
| SRP007169 | IFI27L2 | 83982 | RNAseq | -0.1606 | 0.7711 | |
| SRP008496 | IFI27L2 | 83982 | RNAseq | -0.0200 | 0.9588 | |
| SRP064894 | IFI27L2 | 83982 | RNAseq | 1.0965 | 0.0079 | |
| SRP133303 | IFI27L2 | 83982 | RNAseq | 0.2633 | 0.3196 | |
| SRP159526 | IFI27L2 | 83982 | RNAseq | -0.4640 | 0.0846 | |
| SRP193095 | IFI27L2 | 83982 | RNAseq | -0.0963 | 0.6846 | |
| SRP219564 | IFI27L2 | 83982 | RNAseq | 0.1875 | 0.7597 | |
| TCGA | IFI27L2 | 83982 | RNAseq | 0.6002 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by IFI27L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFI27L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFI27L2 | 83982 | 9 | 4 | 17 | |
| GSE20123 | IFI27L2 | 83982 | 9 | 3 | 18 | |
| GSE43470 | IFI27L2 | 83982 | 7 | 3 | 33 | |
| GSE46452 | IFI27L2 | 83982 | 16 | 3 | 40 | |
| GSE47630 | IFI27L2 | 83982 | 11 | 8 | 21 | |
| GSE54993 | IFI27L2 | 83982 | 3 | 8 | 59 | |
| GSE54994 | IFI27L2 | 83982 | 20 | 4 | 29 | |
| GSE60625 | IFI27L2 | 83982 | 0 | 2 | 9 | |
| GSE74703 | IFI27L2 | 83982 | 6 | 3 | 27 | |
| GSE74704 | IFI27L2 | 83982 | 5 | 3 | 12 | |
| TCGA | IFI27L2 | 83982 | 30 | 20 | 46 |
Total number of gains: 116; Total number of losses: 61; Total Number of normals: 311.
Somatic mutations of IFI27L2:
Generating mutation plots.
Highly correlated genes for IFI27L2:
Showing top 20/549 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFI27L2 | C1RL | 0.800553 | 3 | 0 | 3 |
| IFI27L2 | SSR4 | 0.769201 | 3 | 0 | 3 |
| IFI27L2 | FPGS | 0.759437 | 3 | 0 | 3 |
| IFI27L2 | MMP15 | 0.755426 | 3 | 0 | 3 |
| IFI27L2 | KRTCAP2 | 0.752914 | 3 | 0 | 3 |
| IFI27L2 | RNASEH2C | 0.743928 | 3 | 0 | 3 |
| IFI27L2 | CD47 | 0.736979 | 3 | 0 | 3 |
| IFI27L2 | TM9SF1 | 0.731186 | 3 | 0 | 3 |
| IFI27L2 | CYTH3 | 0.720774 | 3 | 0 | 3 |
| IFI27L2 | SLC2A3 | 0.720046 | 3 | 0 | 3 |
| IFI27L2 | C1orf35 | 0.719732 | 3 | 0 | 3 |
| IFI27L2 | SSB | 0.713172 | 3 | 0 | 3 |
| IFI27L2 | ACVRL1 | 0.704964 | 3 | 0 | 3 |
| IFI27L2 | ENG | 0.70335 | 5 | 0 | 5 |
| IFI27L2 | BHLHE41 | 0.702418 | 3 | 0 | 3 |
| IFI27L2 | MICAL1 | 0.701577 | 3 | 0 | 3 |
| IFI27L2 | LGALS8 | 0.700945 | 3 | 0 | 3 |
| IFI27L2 | SNTA1 | 0.698814 | 3 | 0 | 3 |
| IFI27L2 | TGFBR1 | 0.697025 | 3 | 0 | 3 |
| IFI27L2 | CPT1A | 0.693308 | 3 | 0 | 3 |
For details and further investigation, click here
