| Full name: immunoglobulin mu DNA binding protein 2 | Alias Symbol: ZFAND7|SMUBP2|CATF1|SMARD1|HCSA|HMN6|CMT2S | ||
| Type: protein-coding gene | Cytoband: 11q13.3 | ||
| Entrez ID: 3508 | HGNC ID: HGNC:5542 | Ensembl Gene: ENSG00000132740 | OMIM ID: 600502 |
| Drug and gene relationship at DGIdb | |||
Expression of IGHMBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IGHMBP2 | 3508 | 31861_at | 0.4943 | 0.5150 | |
| GSE20347 | IGHMBP2 | 3508 | 31861_at | 0.4241 | 0.0123 | |
| GSE23400 | IGHMBP2 | 3508 | 31861_at | 0.0528 | 0.2771 | |
| GSE26886 | IGHMBP2 | 3508 | 31861_at | 0.0875 | 0.4930 | |
| GSE29001 | IGHMBP2 | 3508 | 31861_at | -0.1030 | 0.5646 | |
| GSE38129 | IGHMBP2 | 3508 | 31861_at | 0.1493 | 0.3155 | |
| GSE45670 | IGHMBP2 | 3508 | 31861_at | 0.2597 | 0.0194 | |
| GSE53622 | IGHMBP2 | 3508 | 13178 | 0.8610 | 0.0000 | |
| GSE53624 | IGHMBP2 | 3508 | 13178 | 0.7101 | 0.0000 | |
| GSE63941 | IGHMBP2 | 3508 | 31861_at | 0.1676 | 0.5029 | |
| GSE77861 | IGHMBP2 | 3508 | 31861_at | 0.1150 | 0.5626 | |
| GSE97050 | IGHMBP2 | 3508 | A_23_P393713 | 0.1576 | 0.6292 | |
| SRP007169 | IGHMBP2 | 3508 | RNAseq | -0.3092 | 0.5108 | |
| SRP008496 | IGHMBP2 | 3508 | RNAseq | -0.2422 | 0.4536 | |
| SRP064894 | IGHMBP2 | 3508 | RNAseq | 0.6586 | 0.0068 | |
| SRP133303 | IGHMBP2 | 3508 | RNAseq | 1.8877 | 0.0000 | |
| SRP159526 | IGHMBP2 | 3508 | RNAseq | 2.8810 | 0.0005 | |
| SRP193095 | IGHMBP2 | 3508 | RNAseq | 1.3526 | 0.0000 | |
| SRP219564 | IGHMBP2 | 3508 | RNAseq | 1.5061 | 0.0370 | |
| TCGA | IGHMBP2 | 3508 | RNAseq | 0.0857 | 0.4362 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by IGHMBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IGHMBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IGHMBP2 | 3508 | 13 | 2 | 15 | |
| GSE20123 | IGHMBP2 | 3508 | 13 | 2 | 15 | |
| GSE43470 | IGHMBP2 | 3508 | 11 | 3 | 29 | |
| GSE46452 | IGHMBP2 | 3508 | 32 | 1 | 26 | |
| GSE47630 | IGHMBP2 | 3508 | 17 | 2 | 21 | |
| GSE54993 | IGHMBP2 | 3508 | 1 | 16 | 53 | |
| GSE54994 | IGHMBP2 | 3508 | 23 | 3 | 27 | |
| GSE60625 | IGHMBP2 | 3508 | 0 | 3 | 8 | |
| GSE74703 | IGHMBP2 | 3508 | 8 | 2 | 26 | |
| GSE74704 | IGHMBP2 | 3508 | 10 | 0 | 10 | |
| TCGA | IGHMBP2 | 3508 | 49 | 4 | 43 |
Total number of gains: 177; Total number of losses: 38; Total Number of normals: 273.
Somatic mutations of IGHMBP2:
Generating mutation plots.
Highly correlated genes for IGHMBP2:
Showing top 20/252 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IGHMBP2 | HOXD-AS2 | 0.786217 | 3 | 0 | 3 |
| IGHMBP2 | ARVCF | 0.748636 | 4 | 0 | 4 |
| IGHMBP2 | CRB2 | 0.73051 | 3 | 0 | 3 |
| IGHMBP2 | NCAN | 0.718235 | 4 | 0 | 3 |
| IGHMBP2 | CDC34 | 0.717704 | 3 | 0 | 3 |
| IGHMBP2 | PRKAR1B | 0.717353 | 4 | 0 | 3 |
| IGHMBP2 | MAP3K19 | 0.707837 | 3 | 0 | 3 |
| IGHMBP2 | CEMP1 | 0.705152 | 3 | 0 | 3 |
| IGHMBP2 | DMC1 | 0.687137 | 4 | 0 | 4 |
| IGHMBP2 | LIME1 | 0.686929 | 3 | 0 | 3 |
| IGHMBP2 | P2RY4 | 0.686286 | 4 | 0 | 4 |
| IGHMBP2 | ACRV1 | 0.683502 | 3 | 0 | 3 |
| IGHMBP2 | HSF4 | 0.680374 | 5 | 0 | 4 |
| IGHMBP2 | RASL10A | 0.675938 | 3 | 0 | 3 |
| IGHMBP2 | GRIN2C | 0.673549 | 3 | 0 | 3 |
| IGHMBP2 | HTR6 | 0.673548 | 4 | 0 | 4 |
| IGHMBP2 | SHROOM1 | 0.672465 | 3 | 0 | 3 |
| IGHMBP2 | TCP10 | 0.670526 | 4 | 0 | 4 |
| IGHMBP2 | SRD5A2 | 0.662996 | 4 | 0 | 3 |
| IGHMBP2 | SEC14L4 | 0.661982 | 5 | 0 | 4 |
For details and further investigation, click here
