| Full name: cell division cycle 5 like | Alias Symbol: PCDC5RP|hCDC5|CEF1|CDC5 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 988 | HGNC ID: HGNC:1743 | Ensembl Gene: ENSG00000096401 | OMIM ID: 602868 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CDC5L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDC5L | 988 | 209056_s_at | 0.1535 | 0.6021 | |
| GSE20347 | CDC5L | 988 | 209056_s_at | 0.4170 | 0.0266 | |
| GSE23400 | CDC5L | 988 | 209055_s_at | 0.2735 | 0.0000 | |
| GSE26886 | CDC5L | 988 | 209056_s_at | 0.0891 | 0.6432 | |
| GSE29001 | CDC5L | 988 | 209056_s_at | 0.5879 | 0.0073 | |
| GSE38129 | CDC5L | 988 | 209056_s_at | 0.4295 | 0.0014 | |
| GSE45670 | CDC5L | 988 | 209056_s_at | 0.2888 | 0.0597 | |
| GSE53622 | CDC5L | 988 | 78728 | 0.2481 | 0.0000 | |
| GSE53624 | CDC5L | 988 | 78728 | 0.5816 | 0.0000 | |
| GSE63941 | CDC5L | 988 | 209056_s_at | 0.3982 | 0.1594 | |
| GSE77861 | CDC5L | 988 | 209056_s_at | 0.1806 | 0.5071 | |
| GSE97050 | CDC5L | 988 | A_23_P156471 | -0.0643 | 0.8287 | |
| SRP007169 | CDC5L | 988 | RNAseq | -0.3899 | 0.2543 | |
| SRP008496 | CDC5L | 988 | RNAseq | 0.1447 | 0.5142 | |
| SRP064894 | CDC5L | 988 | RNAseq | 0.2482 | 0.1130 | |
| SRP133303 | CDC5L | 988 | RNAseq | 0.3077 | 0.0009 | |
| SRP159526 | CDC5L | 988 | RNAseq | 0.1298 | 0.4874 | |
| SRP193095 | CDC5L | 988 | RNAseq | 0.1167 | 0.2060 | |
| SRP219564 | CDC5L | 988 | RNAseq | 0.1539 | 0.5077 | |
| TCGA | CDC5L | 988 | RNAseq | 0.0539 | 0.2695 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CDC5L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDC5L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDC5L | 988 | 7 | 1 | 22 | |
| GSE20123 | CDC5L | 988 | 7 | 1 | 22 | |
| GSE43470 | CDC5L | 988 | 6 | 0 | 37 | |
| GSE46452 | CDC5L | 988 | 3 | 9 | 47 | |
| GSE47630 | CDC5L | 988 | 8 | 4 | 28 | |
| GSE54993 | CDC5L | 988 | 3 | 2 | 65 | |
| GSE54994 | CDC5L | 988 | 8 | 3 | 42 | |
| GSE60625 | CDC5L | 988 | 0 | 3 | 8 | |
| GSE74703 | CDC5L | 988 | 6 | 0 | 30 | |
| GSE74704 | CDC5L | 988 | 3 | 1 | 16 | |
| TCGA | CDC5L | 988 | 21 | 14 | 61 |
Total number of gains: 72; Total number of losses: 38; Total Number of normals: 378.
Somatic mutations of CDC5L:
Generating mutation plots.
Highly correlated genes for CDC5L:
Showing top 20/919 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDC5L | METTL14 | 0.790275 | 3 | 0 | 3 |
| CDC5L | RPL8 | 0.76183 | 3 | 0 | 3 |
| CDC5L | IL6R | 0.75922 | 3 | 0 | 3 |
| CDC5L | TRAPPC10 | 0.732513 | 3 | 0 | 3 |
| CDC5L | ANAPC4 | 0.709022 | 3 | 0 | 3 |
| CDC5L | DGKH | 0.703442 | 3 | 0 | 3 |
| CDC5L | IMMP1L | 0.702268 | 3 | 0 | 3 |
| CDC5L | PTOV1 | 0.7014 | 4 | 0 | 4 |
| CDC5L | PPIL1 | 0.698591 | 8 | 0 | 8 |
| CDC5L | SLC35B2 | 0.698351 | 4 | 0 | 4 |
| CDC5L | CMTM4 | 0.694528 | 3 | 0 | 3 |
| CDC5L | KRTCAP2 | 0.693097 | 3 | 0 | 3 |
| CDC5L | PPIG | 0.692293 | 4 | 0 | 3 |
| CDC5L | CBFA2T2 | 0.691273 | 3 | 0 | 3 |
| CDC5L | ALKBH3 | 0.68623 | 3 | 0 | 3 |
| CDC5L | RAB34 | 0.682216 | 3 | 0 | 3 |
| CDC5L | SP100 | 0.681644 | 4 | 0 | 3 |
| CDC5L | ABCB10 | 0.681581 | 4 | 0 | 3 |
| CDC5L | CENPQ | 0.680665 | 12 | 0 | 10 |
| CDC5L | RBMX | 0.680402 | 3 | 0 | 3 |
For details and further investigation, click here
