| Full name: centromere protein Q | Alias Symbol: FLJ10545|CENP-Q | ||
| Type: protein-coding gene | Cytoband: 6p12.3 | ||
| Entrez ID: 55166 | HGNC ID: HGNC:21347 | Ensembl Gene: ENSG00000031691 | OMIM ID: 611506 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CENPQ:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CENPQ | 55166 | 219294_at | 0.9125 | 0.0433 | |
| GSE20347 | CENPQ | 55166 | 219294_at | 0.9035 | 0.0002 | |
| GSE23400 | CENPQ | 55166 | 219294_at | 0.2722 | 0.0000 | |
| GSE26886 | CENPQ | 55166 | 219294_at | 0.3320 | 0.1813 | |
| GSE29001 | CENPQ | 55166 | 219294_at | 1.0110 | 0.0070 | |
| GSE38129 | CENPQ | 55166 | 219294_at | 0.9341 | 0.0000 | |
| GSE45670 | CENPQ | 55166 | 219294_at | 0.7234 | 0.0028 | |
| GSE53622 | CENPQ | 55166 | 6931 | 0.7983 | 0.0000 | |
| GSE53624 | CENPQ | 55166 | 6931 | 1.1211 | 0.0000 | |
| GSE63941 | CENPQ | 55166 | 219294_at | 1.0084 | 0.0835 | |
| GSE77861 | CENPQ | 55166 | 219294_at | 0.1024 | 0.7815 | |
| GSE97050 | CENPQ | 55166 | A_23_P70328 | 0.3881 | 0.2767 | |
| SRP007169 | CENPQ | 55166 | RNAseq | 0.9791 | 0.1145 | |
| SRP064894 | CENPQ | 55166 | RNAseq | 0.8497 | 0.0026 | |
| SRP133303 | CENPQ | 55166 | RNAseq | 1.0058 | 0.0000 | |
| SRP159526 | CENPQ | 55166 | RNAseq | 0.4837 | 0.1015 | |
| SRP193095 | CENPQ | 55166 | RNAseq | 0.5286 | 0.0019 | |
| SRP219564 | CENPQ | 55166 | RNAseq | 0.2669 | 0.5469 | |
| TCGA | CENPQ | 55166 | RNAseq | 0.5604 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by CENPQ expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CENPQ:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CENPQ | 55166 | 5 | 2 | 23 | |
| GSE20123 | CENPQ | 55166 | 5 | 2 | 23 | |
| GSE43470 | CENPQ | 55166 | 5 | 0 | 38 | |
| GSE46452 | CENPQ | 55166 | 2 | 10 | 47 | |
| GSE47630 | CENPQ | 55166 | 7 | 5 | 28 | |
| GSE54993 | CENPQ | 55166 | 3 | 1 | 66 | |
| GSE54994 | CENPQ | 55166 | 8 | 4 | 41 | |
| GSE60625 | CENPQ | 55166 | 0 | 3 | 8 | |
| GSE74703 | CENPQ | 55166 | 5 | 0 | 31 | |
| GSE74704 | CENPQ | 55166 | 1 | 1 | 18 | |
| TCGA | CENPQ | 55166 | 21 | 12 | 63 |
Total number of gains: 62; Total number of losses: 40; Total Number of normals: 386.
Somatic mutations of CENPQ:
Generating mutation plots.
Highly correlated genes for CENPQ:
Showing top 20/1630 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CENPQ | GFM1 | 0.738137 | 4 | 0 | 3 |
| CENPQ | MMS22L | 0.737495 | 3 | 0 | 3 |
| CENPQ | PYCR2 | 0.734037 | 3 | 0 | 3 |
| CENPQ | GMNN | 0.732918 | 13 | 0 | 12 |
| CENPQ | SNAP47 | 0.7314 | 3 | 0 | 3 |
| CENPQ | AGTRAP | 0.728738 | 3 | 0 | 3 |
| CENPQ | UHMK1 | 0.726166 | 4 | 0 | 4 |
| CENPQ | SLC7A6OS | 0.725695 | 3 | 0 | 3 |
| CENPQ | GORAB | 0.722383 | 5 | 0 | 5 |
| CENPQ | C1orf112 | 0.720557 | 9 | 0 | 9 |
| CENPQ | FLVCR1 | 0.717595 | 4 | 0 | 4 |
| CENPQ | KIF18A | 0.714237 | 13 | 0 | 12 |
| CENPQ | NLN | 0.714193 | 3 | 0 | 3 |
| CENPQ | MAD2L2 | 0.708815 | 5 | 0 | 4 |
| CENPQ | FXR1 | 0.707228 | 7 | 0 | 7 |
| CENPQ | RAD21 | 0.703282 | 7 | 0 | 6 |
| CENPQ | GTF2E1 | 0.702321 | 10 | 0 | 10 |
| CENPQ | HMMR | 0.702245 | 11 | 0 | 11 |
| CENPQ | SGMS1 | 0.701914 | 3 | 0 | 3 |
| CENPQ | COMMD7 | 0.701766 | 3 | 0 | 3 |
For details and further investigation, click here
