ABCB10

 

Full name: ATP binding cassette subfamily B member 10 Alias Symbol: EST20237|M-ABC2|MTABC2
Type: protein-coding gene Cytoband: 1q42.13
Entrez ID: 23456 HGNC ID: HGNC:41 Ensembl Gene: ENSG00000135776 OMIM ID: 605454
Drug and gene relationship at DGIdb

 

Expression of ABCB10:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ABCB10 23456 223320_s_at 0.1732 0.6656
GSE26886 ABCB10 23456 223320_s_at 0.5714 0.1579
GSE45670 ABCB10 23456 223320_s_at -0.1365 0.4198
GSE53622 ABCB10 23456 69529 -0.0487 0.5840
GSE53624 ABCB10 23456 69529 0.0089 0.9378
GSE63941 ABCB10 23456 223320_s_at -0.8975 0.0290
GSE77861 ABCB10 23456 223320_s_at 0.2369 0.3929
GSE97050 ABCB10 23456 A_23_P201918 0.1423 0.5570
SRP007169 ABCB10 23456 RNAseq -0.5034 0.2231
SRP008496 ABCB10 23456 RNAseq -0.3078 0.3117
SRP064894 ABCB10 23456 RNAseq -0.1389 0.5141
SRP133303 ABCB10 23456 RNAseq 0.2790 0.0421
SRP159526 ABCB10 23456 RNAseq 0.0392 0.9298
SRP193095 ABCB10 23456 RNAseq -0.0135 0.8798
SRP219564 ABCB10 23456 RNAseq -0.3001 0.0648
TCGA ABCB10 23456 RNAseq 0.0053 0.9224

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by ABCB10 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ABCB10:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ABCB10 23456 11 0 19
GSE20123 ABCB10 23456 11 0 19
GSE43470 ABCB10 23456 8 1 34
GSE46452 ABCB10 23456 4 2 53
GSE47630 ABCB10 23456 15 0 25
GSE54993 ABCB10 23456 0 6 64
GSE54994 ABCB10 23456 17 0 36
GSE60625 ABCB10 23456 0 0 11
GSE74703 ABCB10 23456 8 1 27
GSE74704 ABCB10 23456 5 0 15
TCGA ABCB10 23456 45 2 49

Total number of gains: 124; Total number of losses: 12; Total Number of normals: 352.  


 

Somatic mutations of ABCB10:

 

Generating mutation plots.

 

Highly correlated genes for ABCB10:

 

Showing top 20/434 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ABCB10FRS20.808263303
ABCB10POLR3C0.778454303
ABCB10MAN1A20.768839303
ABCB10NUP540.750144404
ABCB10SMC20.747708303
ABCB10GLE10.74632303
ABCB10PPHLN10.74409303
ABCB10FTSJ10.73426303
ABCB10LACTB0.730298404
ABCB10C1D0.728803404
ABCB10FARS20.726956303
ABCB10SLBP0.723109404
ABCB10DPYSL20.721581303
ABCB10LRRC580.720695303
ABCB10STAM20.718968303
ABCB10TCTN30.716016303
ABCB10MIS18A0.714818303
ABCB10SLC30A50.712257505
ABCB10ZNF6490.704556303
ABCB10SMARCAL10.703295303

For details and further investigation, click here