| Full name: cadherin 17 | Alias Symbol: HPT-1|cadherin | ||
| Type: protein-coding gene | Cytoband: 8q22.1 | ||
| Entrez ID: 1015 | HGNC ID: HGNC:1756 | Ensembl Gene: ENSG00000079112 | OMIM ID: 603017 |
| Drug and gene relationship at DGIdb | |||
Expression of CDH17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDH17 | 1015 | 209847_at | -1.0499 | 0.1175 | |
| GSE20347 | CDH17 | 1015 | 209847_at | -0.2635 | 0.0496 | |
| GSE23400 | CDH17 | 1015 | 209847_at | -0.1210 | 0.0041 | |
| GSE26886 | CDH17 | 1015 | 209847_at | -0.5772 | 0.0664 | |
| GSE29001 | CDH17 | 1015 | 209847_at | -0.5810 | 0.0064 | |
| GSE38129 | CDH17 | 1015 | 209847_at | -0.3475 | 0.0026 | |
| GSE45670 | CDH17 | 1015 | 209847_at | -0.1971 | 0.3580 | |
| GSE53622 | CDH17 | 1015 | 18163 | -1.3818 | 0.0000 | |
| GSE53624 | CDH17 | 1015 | 18163 | -1.7311 | 0.0000 | |
| GSE63941 | CDH17 | 1015 | 209847_at | -0.0625 | 0.7018 | |
| GSE77861 | CDH17 | 1015 | 209847_at | -0.2293 | 0.0304 | |
| SRP007169 | CDH17 | 1015 | RNAseq | -2.1781 | 0.0065 | |
| SRP133303 | CDH17 | 1015 | RNAseq | -1.5041 | 0.0000 | |
| SRP159526 | CDH17 | 1015 | RNAseq | -2.2878 | 0.0002 | |
| SRP193095 | CDH17 | 1015 | RNAseq | -2.1364 | 0.0000 | |
| SRP219564 | CDH17 | 1015 | RNAseq | -1.7927 | 0.0113 | |
| TCGA | CDH17 | 1015 | RNAseq | -0.5110 | 0.2644 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by CDH17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDH17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDH17 | 1015 | 16 | 0 | 14 | |
| GSE20123 | CDH17 | 1015 | 17 | 0 | 13 | |
| GSE43470 | CDH17 | 1015 | 21 | 1 | 21 | |
| GSE46452 | CDH17 | 1015 | 22 | 0 | 37 | |
| GSE47630 | CDH17 | 1015 | 24 | 0 | 16 | |
| GSE54993 | CDH17 | 1015 | 0 | 20 | 50 | |
| GSE54994 | CDH17 | 1015 | 34 | 1 | 18 | |
| GSE60625 | CDH17 | 1015 | 0 | 4 | 7 | |
| GSE74703 | CDH17 | 1015 | 18 | 1 | 17 | |
| GSE74704 | CDH17 | 1015 | 12 | 0 | 8 | |
| TCGA | CDH17 | 1015 | 56 | 1 | 39 |
Total number of gains: 220; Total number of losses: 28; Total Number of normals: 240.
Somatic mutations of CDH17:
Generating mutation plots.
Highly correlated genes for CDH17:
Showing top 20/940 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDH17 | EDDM3A | 0.700427 | 3 | 0 | 3 |
| CDH17 | MPP7 | 0.679742 | 5 | 0 | 5 |
| CDH17 | FAM107A | 0.675792 | 5 | 0 | 5 |
| CDH17 | MAML3 | 0.665812 | 6 | 0 | 6 |
| CDH17 | KIR2DS2 | 0.664154 | 5 | 0 | 5 |
| CDH17 | LINC00032 | 0.663379 | 3 | 0 | 3 |
| CDH17 | GREM2 | 0.65647 | 4 | 0 | 4 |
| CDH17 | EPS8L3 | 0.656226 | 6 | 0 | 4 |
| CDH17 | CRHR2 | 0.654358 | 5 | 0 | 4 |
| CDH17 | SMIM5 | 0.652937 | 4 | 0 | 4 |
| CDH17 | OR5I1 | 0.652182 | 5 | 0 | 4 |
| CDH17 | MTPN | 0.648129 | 4 | 0 | 4 |
| CDH17 | FCHO2 | 0.645574 | 6 | 0 | 6 |
| CDH17 | CD200R1 | 0.644957 | 5 | 0 | 5 |
| CDH17 | GBP6 | 0.641882 | 3 | 0 | 3 |
| CDH17 | PLCXD3 | 0.640691 | 4 | 0 | 4 |
| CDH17 | RAB11B-AS1 | 0.639421 | 3 | 0 | 3 |
| CDH17 | FGR | 0.63896 | 5 | 0 | 4 |
| CDH17 | GABRA5 | 0.637983 | 3 | 0 | 3 |
| CDH17 | MCEE | 0.635674 | 5 | 0 | 5 |
For details and further investigation, click here
