| Full name: family with sequence similarity 107 member A | Alias Symbol: DRR1|TU3A | ||
| Type: protein-coding gene | Cytoband: 3p14.3-p14.2 | ||
| Entrez ID: 11170 | HGNC ID: HGNC:30827 | Ensembl Gene: ENSG00000168309 | OMIM ID: 608295 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM107A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM107A | 11170 | 209074_s_at | -2.3188 | 0.0559 | |
| GSE20347 | FAM107A | 11170 | 209074_s_at | -0.9803 | 0.0000 | |
| GSE23400 | FAM107A | 11170 | 209074_s_at | -1.2101 | 0.0000 | |
| GSE26886 | FAM107A | 11170 | 207547_s_at | -0.2414 | 0.0691 | |
| GSE29001 | FAM107A | 11170 | 209074_s_at | -0.7459 | 0.0109 | |
| GSE38129 | FAM107A | 11170 | 209074_s_at | -1.8059 | 0.0000 | |
| GSE45670 | FAM107A | 11170 | 207547_s_at | -0.6641 | 0.0000 | |
| GSE53622 | FAM107A | 11170 | 5568 | -3.1008 | 0.0000 | |
| GSE53624 | FAM107A | 11170 | 5568 | -2.9488 | 0.0000 | |
| GSE63941 | FAM107A | 11170 | 207547_s_at | 0.1296 | 0.2979 | |
| GSE77861 | FAM107A | 11170 | 207547_s_at | -0.0748 | 0.7061 | |
| GSE97050 | FAM107A | 11170 | A_23_P84860 | -0.8150 | 0.1711 | |
| SRP064894 | FAM107A | 11170 | RNAseq | -1.4403 | 0.0071 | |
| SRP133303 | FAM107A | 11170 | RNAseq | -2.4269 | 0.0000 | |
| SRP159526 | FAM107A | 11170 | RNAseq | -1.9313 | 0.0061 | |
| SRP193095 | FAM107A | 11170 | RNAseq | -0.6570 | 0.0022 | |
| SRP219564 | FAM107A | 11170 | RNAseq | -1.5390 | 0.0736 | |
| TCGA | FAM107A | 11170 | RNAseq | -1.8177 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by FAM107A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM107A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM107A | 11170 | 0 | 17 | 13 | |
| GSE20123 | FAM107A | 11170 | 0 | 18 | 12 | |
| GSE43470 | FAM107A | 11170 | 0 | 17 | 26 | |
| GSE46452 | FAM107A | 11170 | 2 | 17 | 40 | |
| GSE47630 | FAM107A | 11170 | 1 | 24 | 15 | |
| GSE54993 | FAM107A | 11170 | 6 | 2 | 62 | |
| GSE54994 | FAM107A | 11170 | 0 | 32 | 21 | |
| GSE60625 | FAM107A | 11170 | 5 | 0 | 6 | |
| GSE74703 | FAM107A | 11170 | 0 | 14 | 22 | |
| GSE74704 | FAM107A | 11170 | 0 | 11 | 9 | |
| TCGA | FAM107A | 11170 | 0 | 79 | 17 |
Total number of gains: 14; Total number of losses: 231; Total Number of normals: 243.
Somatic mutations of FAM107A:
Generating mutation plots.
Highly correlated genes for FAM107A:
Showing top 20/1128 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM107A | RBFOX3 | 0.862843 | 3 | 0 | 3 |
| FAM107A | PLCXD3 | 0.845878 | 4 | 0 | 4 |
| FAM107A | MYZAP | 0.817883 | 3 | 0 | 3 |
| FAM107A | CYP21A2 | 0.805956 | 3 | 0 | 3 |
| FAM107A | ACKR1 | 0.776221 | 9 | 0 | 9 |
| FAM107A | LRRTM1 | 0.774407 | 3 | 0 | 3 |
| FAM107A | ADAMTS9-AS2 | 0.769103 | 4 | 0 | 4 |
| FAM107A | CFD | 0.766094 | 10 | 0 | 10 |
| FAM107A | CDH19 | 0.753893 | 8 | 0 | 8 |
| FAM107A | CLDN5 | 0.750863 | 8 | 0 | 8 |
| FAM107A | RAI2 | 0.75055 | 8 | 0 | 7 |
| FAM107A | ADH1B | 0.748801 | 9 | 0 | 9 |
| FAM107A | ADCY5 | 0.748079 | 5 | 0 | 5 |
| FAM107A | PTGIS | 0.746333 | 6 | 0 | 6 |
| FAM107A | GNA14 | 0.732431 | 8 | 0 | 8 |
| FAM107A | RERGL | 0.729314 | 8 | 0 | 7 |
| FAM107A | TACC1 | 0.728271 | 8 | 0 | 7 |
| FAM107A | FGF10 | 0.726626 | 4 | 0 | 3 |
| FAM107A | SCN7A | 0.726004 | 9 | 0 | 9 |
| FAM107A | RSPO1 | 0.724414 | 5 | 0 | 5 |
For details and further investigation, click here
