MYOZ3

 

Full name: myozenin 3 Alias Symbol: CS-3|CS3|FRP3|FATZ-3
Type: protein-coding gene Cytoband: 5q33.1
Entrez ID: 91977 HGNC ID: HGNC:18565 Ensembl Gene: ENSG00000164591 OMIM ID: 610735
Drug and gene relationship at DGIdb

 

Expression of MYOZ3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MYOZ3 91977 1562002_at -0.1442 0.5862
GSE20347 MYOZ3 91977 213955_at -0.0186 0.8578
GSE23400 MYOZ3 91977 213955_at -0.0909 0.0600
GSE26886 MYOZ3 91977 1562002_at 0.0188 0.8942
GSE29001 MYOZ3 91977 213955_at -0.1436 0.5555
GSE38129 MYOZ3 91977 213955_at -0.2487 0.0106
GSE45670 MYOZ3 91977 1562002_at -0.0439 0.6290
GSE53622 MYOZ3 91977 68869 0.2206 0.0427
GSE53624 MYOZ3 91977 68869 0.2036 0.0404
GSE63941 MYOZ3 91977 1562002_at 0.2581 0.0480
GSE77861 MYOZ3 91977 1562002_at -0.0172 0.8927
GSE97050 MYOZ3 91977 A_32_P88415 0.2602 0.3225
SRP133303 MYOZ3 91977 RNAseq -0.0959 0.6275
SRP159526 MYOZ3 91977 RNAseq 0.0353 0.9531
SRP219564 MYOZ3 91977 RNAseq -0.2183 0.7237
TCGA MYOZ3 91977 RNAseq -0.8027 0.0364

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by MYOZ3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of MYOZ3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MYOZ3 91977 1 12 17
GSE20123 MYOZ3 91977 1 12 17
GSE43470 MYOZ3 91977 1 10 32
GSE46452 MYOZ3 91977 0 27 32
GSE47630 MYOZ3 91977 0 20 20
GSE54993 MYOZ3 91977 9 1 60
GSE54994 MYOZ3 91977 2 15 36
GSE60625 MYOZ3 91977 0 0 11
GSE74703 MYOZ3 91977 1 7 28
GSE74704 MYOZ3 91977 1 7 12
TCGA MYOZ3 91977 5 37 54

Total number of gains: 21; Total number of losses: 148; Total Number of normals: 319.  


 

Somatic mutations of MYOZ3:

 

Generating mutation plots.

 

Highly correlated genes for MYOZ3:

 

Showing top 20/1128 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MYOZ3FOXA30.819179303
MYOZ3PNPLA70.793483303
MYOZ3PRR180.784524303
MYOZ3TMEM229A0.779229303
MYOZ3SPACA30.772943303
MYOZ3STRC0.771612303
MYOZ3KCTD190.771297303
MYOZ3C9orf1530.768442303
MYOZ3OR2T270.76348303
MYOZ3PALM30.741469404
MYOZ3LINC008870.736747303
MYOZ3DCDC10.732637303
MYOZ3MUC3A0.730354303
MYOZ3DEFB1280.73018303
MYOZ3GABRB10.72541404
MYOZ3KIFC20.724244303
MYOZ3SPEF20.723484303
MYOZ3MRGPRG0.721881303
MYOZ3YY20.721241303
MYOZ3TMEM1050.717371505

For details and further investigation, click here