| Full name: CDK5 regulatory subunit associated protein 2 | Alias Symbol: C48|FLJ10867|CEP215 | ||
| Type: protein-coding gene | Cytoband: 9q33.2 | ||
| Entrez ID: 55755 | HGNC ID: HGNC:18672 | Ensembl Gene: ENSG00000136861 | OMIM ID: 608201 |
| Drug and gene relationship at DGIdb | |||
Expression of CDK5RAP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDK5RAP2 | 55755 | 233540_s_at | -0.1414 | 0.8164 | |
| GSE20347 | CDK5RAP2 | 55755 | 220935_s_at | 0.4461 | 0.0955 | |
| GSE23400 | CDK5RAP2 | 55755 | 220935_s_at | 0.2895 | 0.0058 | |
| GSE26886 | CDK5RAP2 | 55755 | 233540_s_at | 2.0048 | 0.0000 | |
| GSE29001 | CDK5RAP2 | 55755 | 220935_s_at | 0.1620 | 0.5288 | |
| GSE38129 | CDK5RAP2 | 55755 | 220935_s_at | 0.4716 | 0.0546 | |
| GSE45670 | CDK5RAP2 | 55755 | 233540_s_at | 0.1251 | 0.8029 | |
| GSE53622 | CDK5RAP2 | 55755 | 66861 | 0.4993 | 0.0000 | |
| GSE53624 | CDK5RAP2 | 55755 | 66861 | 0.6273 | 0.0000 | |
| GSE63941 | CDK5RAP2 | 55755 | 220935_s_at | 0.1317 | 0.8262 | |
| GSE77861 | CDK5RAP2 | 55755 | 220935_s_at | 0.2075 | 0.3323 | |
| GSE97050 | CDK5RAP2 | 55755 | A_33_P3389060 | -0.2530 | 0.3580 | |
| SRP007169 | CDK5RAP2 | 55755 | RNAseq | 1.5979 | 0.0006 | |
| SRP008496 | CDK5RAP2 | 55755 | RNAseq | 2.0529 | 0.0000 | |
| SRP064894 | CDK5RAP2 | 55755 | RNAseq | 0.2195 | 0.1728 | |
| SRP133303 | CDK5RAP2 | 55755 | RNAseq | -0.0539 | 0.6349 | |
| SRP159526 | CDK5RAP2 | 55755 | RNAseq | 0.8894 | 0.0175 | |
| SRP193095 | CDK5RAP2 | 55755 | RNAseq | 0.5160 | 0.0016 | |
| SRP219564 | CDK5RAP2 | 55755 | RNAseq | -0.1967 | 0.5111 | |
| TCGA | CDK5RAP2 | 55755 | RNAseq | -0.0196 | 0.7648 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by CDK5RAP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDK5RAP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDK5RAP2 | 55755 | 4 | 7 | 19 | |
| GSE20123 | CDK5RAP2 | 55755 | 4 | 7 | 19 | |
| GSE43470 | CDK5RAP2 | 55755 | 5 | 4 | 34 | |
| GSE46452 | CDK5RAP2 | 55755 | 6 | 13 | 40 | |
| GSE47630 | CDK5RAP2 | 55755 | 3 | 16 | 21 | |
| GSE54993 | CDK5RAP2 | 55755 | 3 | 3 | 64 | |
| GSE54994 | CDK5RAP2 | 55755 | 9 | 10 | 34 | |
| GSE60625 | CDK5RAP2 | 55755 | 0 | 0 | 11 | |
| GSE74703 | CDK5RAP2 | 55755 | 5 | 3 | 28 | |
| GSE74704 | CDK5RAP2 | 55755 | 2 | 5 | 13 | |
| TCGA | CDK5RAP2 | 55755 | 27 | 25 | 44 |
Total number of gains: 68; Total number of losses: 93; Total Number of normals: 327.
Somatic mutations of CDK5RAP2:
Generating mutation plots.
Highly correlated genes for CDK5RAP2:
Showing top 20/373 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDK5RAP2 | TMCC3 | 0.825691 | 3 | 0 | 3 |
| CDK5RAP2 | TMTC3 | 0.777046 | 3 | 0 | 3 |
| CDK5RAP2 | AKAP8 | 0.767743 | 3 | 0 | 3 |
| CDK5RAP2 | TBC1D2 | 0.761882 | 3 | 0 | 3 |
| CDK5RAP2 | GPHN | 0.752793 | 3 | 0 | 3 |
| CDK5RAP2 | RIMKLA | 0.751635 | 3 | 0 | 3 |
| CDK5RAP2 | NRIP1 | 0.749988 | 3 | 0 | 3 |
| CDK5RAP2 | STK32B | 0.748038 | 3 | 0 | 3 |
| CDK5RAP2 | TMEM107 | 0.747503 | 3 | 0 | 3 |
| CDK5RAP2 | KRTCAP2 | 0.745239 | 3 | 0 | 3 |
| CDK5RAP2 | MORC4 | 0.744158 | 4 | 0 | 4 |
| CDK5RAP2 | ZFP90 | 0.742134 | 3 | 0 | 3 |
| CDK5RAP2 | DEDD | 0.738685 | 3 | 0 | 3 |
| CDK5RAP2 | TIGD1 | 0.738177 | 3 | 0 | 3 |
| CDK5RAP2 | HERC2 | 0.734364 | 3 | 0 | 3 |
| CDK5RAP2 | DDX54 | 0.732472 | 3 | 0 | 3 |
| CDK5RAP2 | METTL23 | 0.730484 | 3 | 0 | 3 |
| CDK5RAP2 | ALG13 | 0.727373 | 3 | 0 | 3 |
| CDK5RAP2 | TEAD4 | 0.725865 | 4 | 0 | 3 |
| CDK5RAP2 | DERL1 | 0.720171 | 3 | 0 | 3 |
For details and further investigation, click here
