| Full name: nuclear receptor interacting protein 1 | Alias Symbol: RIP140 | ||
| Type: protein-coding gene | Cytoband: 21q11.2-q21.1 | ||
| Entrez ID: 8204 | HGNC ID: HGNC:8001 | Ensembl Gene: ENSG00000180530 | OMIM ID: 602490 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NRIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NRIP1 | 8204 | 202599_s_at | 0.3208 | 0.4540 | |
| GSE20347 | NRIP1 | 8204 | 202600_s_at | -0.1028 | 0.7526 | |
| GSE23400 | NRIP1 | 8204 | 202599_s_at | 0.3922 | 0.0035 | |
| GSE26886 | NRIP1 | 8204 | 202599_s_at | 0.3356 | 0.2034 | |
| GSE29001 | NRIP1 | 8204 | 202599_s_at | -0.2454 | 0.6709 | |
| GSE38129 | NRIP1 | 8204 | 202599_s_at | -0.0200 | 0.9367 | |
| GSE45670 | NRIP1 | 8204 | 202599_s_at | 0.4428 | 0.1064 | |
| GSE53622 | NRIP1 | 8204 | 56635 | 0.3102 | 0.0096 | |
| GSE53624 | NRIP1 | 8204 | 56635 | 0.3349 | 0.0038 | |
| GSE63941 | NRIP1 | 8204 | 202599_s_at | -0.0879 | 0.9234 | |
| GSE77861 | NRIP1 | 8204 | 202599_s_at | 0.5660 | 0.1943 | |
| GSE97050 | NRIP1 | 8204 | A_23_P211007 | 0.4433 | 0.1334 | |
| SRP007169 | NRIP1 | 8204 | RNAseq | 0.4052 | 0.2444 | |
| SRP008496 | NRIP1 | 8204 | RNAseq | 1.0536 | 0.0101 | |
| SRP064894 | NRIP1 | 8204 | RNAseq | 0.4788 | 0.0598 | |
| SRP133303 | NRIP1 | 8204 | RNAseq | 0.5585 | 0.0295 | |
| SRP159526 | NRIP1 | 8204 | RNAseq | 0.0657 | 0.8686 | |
| SRP193095 | NRIP1 | 8204 | RNAseq | 0.3519 | 0.0313 | |
| SRP219564 | NRIP1 | 8204 | RNAseq | -0.0446 | 0.9161 | |
| TCGA | NRIP1 | 8204 | RNAseq | 0.1480 | 0.0775 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NRIP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NRIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NRIP1 | 8204 | 2 | 9 | 19 | |
| GSE20123 | NRIP1 | 8204 | 2 | 9 | 19 | |
| GSE43470 | NRIP1 | 8204 | 2 | 11 | 30 | |
| GSE46452 | NRIP1 | 8204 | 1 | 22 | 36 | |
| GSE47630 | NRIP1 | 8204 | 6 | 17 | 17 | |
| GSE54993 | NRIP1 | 8204 | 9 | 1 | 60 | |
| GSE54994 | NRIP1 | 8204 | 3 | 10 | 40 | |
| GSE60625 | NRIP1 | 8204 | 0 | 0 | 11 | |
| GSE74703 | NRIP1 | 8204 | 2 | 8 | 26 | |
| GSE74704 | NRIP1 | 8204 | 2 | 6 | 12 | |
| TCGA | NRIP1 | 8204 | 14 | 39 | 43 |
Total number of gains: 43; Total number of losses: 132; Total Number of normals: 313.
Somatic mutations of NRIP1:
Generating mutation plots.
Highly correlated genes for NRIP1:
Showing top 20/316 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NRIP1 | GSS | 0.787636 | 3 | 0 | 3 |
| NRIP1 | DARS2 | 0.762935 | 3 | 0 | 3 |
| NRIP1 | CDK5RAP2 | 0.749988 | 3 | 0 | 3 |
| NRIP1 | HTRA2 | 0.723714 | 3 | 0 | 3 |
| NRIP1 | TMEM237 | 0.70599 | 3 | 0 | 3 |
| NRIP1 | SLC2A9 | 0.700113 | 3 | 0 | 3 |
| NRIP1 | B4GALT3 | 0.698674 | 3 | 0 | 3 |
| NRIP1 | BRAT1 | 0.696028 | 3 | 0 | 3 |
| NRIP1 | PRPS1 | 0.695478 | 3 | 0 | 3 |
| NRIP1 | CSTF3 | 0.694088 | 3 | 0 | 3 |
| NRIP1 | BCL9L | 0.69352 | 3 | 0 | 3 |
| NRIP1 | RFWD3 | 0.692397 | 3 | 0 | 3 |
| NRIP1 | FHOD1 | 0.691049 | 5 | 0 | 4 |
| NRIP1 | CDC42SE2 | 0.689277 | 3 | 0 | 3 |
| NRIP1 | PAK1 | 0.688985 | 3 | 0 | 3 |
| NRIP1 | C6orf141 | 0.688187 | 5 | 0 | 4 |
| NRIP1 | SRSF1 | 0.679283 | 3 | 0 | 3 |
| NRIP1 | STON2 | 0.675074 | 5 | 0 | 5 |
| NRIP1 | CHST11 | 0.674077 | 4 | 0 | 3 |
| NRIP1 | SEC22C | 0.67377 | 3 | 0 | 3 |
For details and further investigation, click here
