TBC1D2

 

Full name: TBC1 domain family member 2 Alias Symbol: PARIS1|TBC1D2A|Armus
Type: protein-coding gene Cytoband: 9q22.33
Entrez ID: 55357 HGNC ID: HGNC:18026 Ensembl Gene: ENSG00000095383 OMIM ID: 609871
Drug and gene relationship at DGIdb

 

Expression of TBC1D2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TBC1D2 55357 222173_s_at -0.1028 0.9300
GSE20347 TBC1D2 55357 222173_s_at -0.3976 0.0550
GSE23400 TBC1D2 55357 222173_s_at 0.0949 0.3255
GSE26886 TBC1D2 55357 222173_s_at -0.0186 0.9374
GSE29001 TBC1D2 55357 222173_s_at 0.0429 0.9088
GSE38129 TBC1D2 55357 222173_s_at 0.2083 0.4954
GSE45670 TBC1D2 55357 222173_s_at 0.4104 0.0148
GSE53622 TBC1D2 55357 39529 -0.1637 0.3854
GSE53624 TBC1D2 55357 39529 -0.0350 0.7485
GSE63941 TBC1D2 55357 222173_s_at 1.0258 0.1947
GSE77861 TBC1D2 55357 222173_s_at 0.1402 0.6669
GSE97050 TBC1D2 55357 A_33_P3216292 0.6474 0.3715
SRP007169 TBC1D2 55357 RNAseq 0.1394 0.8071
SRP008496 TBC1D2 55357 RNAseq -0.0869 0.8109
SRP064894 TBC1D2 55357 RNAseq 0.3883 0.1119
SRP133303 TBC1D2 55357 RNAseq 0.3471 0.2328
SRP159526 TBC1D2 55357 RNAseq -0.5681 0.1531
SRP193095 TBC1D2 55357 RNAseq 0.2302 0.3552
SRP219564 TBC1D2 55357 RNAseq 0.0200 0.9751
TCGA TBC1D2 55357 RNAseq 0.4501 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TBC1D2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TBC1D2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TBC1D2 55357 4 9 17
GSE20123 TBC1D2 55357 5 8 17
GSE43470 TBC1D2 55357 6 3 34
GSE46452 TBC1D2 55357 6 14 39
GSE47630 TBC1D2 55357 1 17 22
GSE54993 TBC1D2 55357 3 3 64
GSE54994 TBC1D2 55357 8 11 34
GSE60625 TBC1D2 55357 0 0 11
GSE74703 TBC1D2 55357 5 3 28
GSE74704 TBC1D2 55357 3 5 12
TCGA TBC1D2 55357 27 22 47

Total number of gains: 68; Total number of losses: 95; Total Number of normals: 325.  

 

Somatic mutations of TBC1D2:

 

Generating mutation plots.

 

Highly correlated genes for TBC1D2:

 

Showing top 20/512 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TBC1D2MFN10.774171303
TBC1D2ATP11B0.762738303
TBC1D2CDK5RAP20.761882303
TBC1D2SLC30A60.748008303
TBC1D2SLC25A430.733044303
TBC1D2SNRPA10.730468303
TBC1D2MREG0.725537504
TBC1D2FOPNL0.719292303
TBC1D2C12orf660.715663303
TBC1D2SREBF20.713603303
TBC1D2RAC20.712898303
TBC1D2CTSH0.711943303
TBC1D2FAM49B0.708713303
TBC1D2SLC50A10.706981403
TBC1D2RIPK30.705952303
TBC1D2CNOT10.69687303
TBC1D2TTF20.695633404
TBC1D2EFHD20.694776303
TBC1D2PPP1CA0.694386404
TBC1D2FBXO390.691508303

For details and further investigation, click here