| Full name: nuclear pore associated protein 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 15q11.2 | ||
| Entrez ID: 23742 | HGNC ID: HGNC:1190 | Ensembl Gene: ENSG00000185823 | OMIM ID: 610922 |
| Drug and gene relationship at DGIdb | |||
Expression of NPAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NPAP1 | 23742 | 221300_at | -0.0761 | 0.8089 | |
| GSE20347 | NPAP1 | 23742 | 221300_at | -0.1396 | 0.1512 | |
| GSE23400 | NPAP1 | 23742 | 221300_at | -0.2321 | 0.0000 | |
| GSE26886 | NPAP1 | 23742 | 221300_at | -0.1301 | 0.3135 | |
| GSE29001 | NPAP1 | 23742 | 221300_at | -0.1762 | 0.1855 | |
| GSE38129 | NPAP1 | 23742 | 221300_at | -0.1055 | 0.2718 | |
| GSE45670 | NPAP1 | 23742 | 221300_at | -0.0964 | 0.4093 | |
| GSE63941 | NPAP1 | 23742 | 221300_at | -0.1623 | 0.4101 | |
| GSE77861 | NPAP1 | 23742 | 221300_at | -0.0515 | 0.6336 | |
| SRP064894 | NPAP1 | 23742 | RNAseq | -0.3256 | 0.1559 | |
| SRP133303 | NPAP1 | 23742 | RNAseq | 0.0194 | 0.9012 | |
| SRP159526 | NPAP1 | 23742 | RNAseq | -0.0419 | 0.8807 | |
| SRP193095 | NPAP1 | 23742 | RNAseq | -0.0763 | 0.5874 | |
| SRP219564 | NPAP1 | 23742 | RNAseq | -0.1222 | 0.7840 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of NPAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NPAP1 | 23742 | 2 | 7 | 21 | |
| GSE20123 | NPAP1 | 23742 | 2 | 7 | 21 | |
| GSE43470 | NPAP1 | 23742 | 3 | 5 | 35 | |
| GSE46452 | NPAP1 | 23742 | 3 | 7 | 49 | |
| GSE47630 | NPAP1 | 23742 | 8 | 11 | 21 | |
| GSE54993 | NPAP1 | 23742 | 4 | 6 | 60 | |
| GSE54994 | NPAP1 | 23742 | 7 | 6 | 40 | |
| GSE60625 | NPAP1 | 23742 | 4 | 3 | 4 | |
| GSE74703 | NPAP1 | 23742 | 3 | 3 | 30 | |
| GSE74704 | NPAP1 | 23742 | 1 | 5 | 14 | |
| TCGA | NPAP1 | 23742 | 17 | 20 | 59 |
Total number of gains: 54; Total number of losses: 80; Total Number of normals: 354.
Somatic mutations of NPAP1:
Generating mutation plots.
Highly correlated genes for NPAP1:
Showing top 20/862 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NPAP1 | PHLDB1 | 0.777684 | 4 | 0 | 4 |
| NPAP1 | PRL | 0.772756 | 4 | 0 | 4 |
| NPAP1 | MUC5AC | 0.767153 | 3 | 0 | 3 |
| NPAP1 | INO80D | 0.743633 | 4 | 0 | 4 |
| NPAP1 | OVGP1 | 0.729241 | 3 | 0 | 3 |
| NPAP1 | PHF7 | 0.725243 | 4 | 0 | 4 |
| NPAP1 | RGSL1 | 0.718187 | 4 | 0 | 4 |
| NPAP1 | IFNA21 | 0.713947 | 4 | 0 | 4 |
| NPAP1 | BPY2 | 0.713651 | 4 | 0 | 4 |
| NPAP1 | DRD5 | 0.70277 | 5 | 0 | 5 |
| NPAP1 | CETN1 | 0.698068 | 4 | 0 | 4 |
| NPAP1 | SCGN | 0.698042 | 3 | 0 | 3 |
| NPAP1 | KLK3 | 0.697724 | 4 | 0 | 4 |
| NPAP1 | ZNF835 | 0.696284 | 3 | 0 | 3 |
| NPAP1 | GABRA4 | 0.691503 | 4 | 0 | 4 |
| NPAP1 | IL18BP | 0.69114 | 4 | 0 | 4 |
| NPAP1 | CDKL5 | 0.68893 | 5 | 0 | 5 |
| NPAP1 | PIWIL2 | 0.685984 | 4 | 0 | 4 |
| NPAP1 | EPOR | 0.68575 | 5 | 0 | 4 |
| NPAP1 | GJB4 | 0.684875 | 5 | 0 | 4 |
For details and further investigation, click here
