| Full name: catenin alpha 1 | Alias Symbol: CAP102 | ||
| Type: protein-coding gene | Cytoband: 5q31.2 | ||
| Entrez ID: 1495 | HGNC ID: HGNC:2509 | Ensembl Gene: ENSG00000044115 | OMIM ID: 116805 |
| Drug and gene relationship at DGIdb | |||
CTNNA1 involved pathways:
Expression of CTNNA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CTNNA1 | 1495 | 210844_x_at | -0.6297 | 0.0768 | |
| GSE20347 | CTNNA1 | 1495 | 210844_x_at | -0.7646 | 0.0000 | |
| GSE23400 | CTNNA1 | 1495 | 210844_x_at | -0.6198 | 0.0000 | |
| GSE26886 | CTNNA1 | 1495 | 210844_x_at | -0.4919 | 0.0139 | |
| GSE29001 | CTNNA1 | 1495 | 200765_x_at | -0.7288 | 0.0002 | |
| GSE38129 | CTNNA1 | 1495 | 210844_x_at | -0.6148 | 0.0000 | |
| GSE45670 | CTNNA1 | 1495 | 210844_x_at | -0.2169 | 0.1630 | |
| GSE53622 | CTNNA1 | 1495 | 32577 | -0.6886 | 0.0000 | |
| GSE53624 | CTNNA1 | 1495 | 32577 | -0.7139 | 0.0000 | |
| GSE63941 | CTNNA1 | 1495 | 210844_x_at | -0.3023 | 0.8370 | |
| GSE77861 | CTNNA1 | 1495 | 210844_x_at | -0.4541 | 0.0833 | |
| GSE97050 | CTNNA1 | 1495 | A_33_P3403418 | -0.3877 | 0.2569 | |
| SRP007169 | CTNNA1 | 1495 | RNAseq | -0.5915 | 0.2704 | |
| SRP008496 | CTNNA1 | 1495 | RNAseq | -0.6548 | 0.0495 | |
| SRP064894 | CTNNA1 | 1495 | RNAseq | -0.9075 | 0.0000 | |
| SRP133303 | CTNNA1 | 1495 | RNAseq | -0.0914 | 0.7437 | |
| SRP159526 | CTNNA1 | 1495 | RNAseq | -1.0256 | 0.0001 | |
| SRP193095 | CTNNA1 | 1495 | RNAseq | -0.9567 | 0.0000 | |
| SRP219564 | CTNNA1 | 1495 | RNAseq | -0.7250 | 0.0032 | |
| TCGA | CTNNA1 | 1495 | RNAseq | -0.0781 | 0.0443 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CTNNA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CTNNA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CTNNA1 | 1495 | 3 | 11 | 16 | |
| GSE20123 | CTNNA1 | 1495 | 4 | 11 | 15 | |
| GSE43470 | CTNNA1 | 1495 | 4 | 5 | 34 | |
| GSE46452 | CTNNA1 | 1495 | 0 | 27 | 32 | |
| GSE47630 | CTNNA1 | 1495 | 0 | 21 | 19 | |
| GSE54993 | CTNNA1 | 1495 | 9 | 1 | 60 | |
| GSE54994 | CTNNA1 | 1495 | 3 | 13 | 37 | |
| GSE60625 | CTNNA1 | 1495 | 0 | 0 | 11 | |
| GSE74703 | CTNNA1 | 1495 | 3 | 4 | 29 | |
| GSE74704 | CTNNA1 | 1495 | 3 | 5 | 12 | |
| TCGA | CTNNA1 | 1495 | 4 | 37 | 55 |
Total number of gains: 33; Total number of losses: 135; Total Number of normals: 320.
Somatic mutations of CTNNA1:
Generating mutation plots.
Highly correlated genes for CTNNA1:
Showing top 20/1536 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CTNNA1 | FCHO2 | 0.770738 | 7 | 0 | 7 |
| CTNNA1 | PINK1 | 0.748155 | 9 | 0 | 9 |
| CTNNA1 | LRP10 | 0.741519 | 11 | 0 | 11 |
| CTNNA1 | SASH1 | 0.741112 | 11 | 0 | 11 |
| CTNNA1 | LRRFIP2 | 0.738363 | 11 | 0 | 11 |
| CTNNA1 | GBP6 | 0.736727 | 3 | 0 | 3 |
| CTNNA1 | SCNN1B | 0.733535 | 10 | 0 | 10 |
| CTNNA1 | VSIG10L | 0.733424 | 6 | 0 | 5 |
| CTNNA1 | NAGK | 0.732604 | 11 | 0 | 10 |
| CTNNA1 | UBL3 | 0.729828 | 10 | 0 | 10 |
| CTNNA1 | ALS2CL | 0.728252 | 9 | 0 | 9 |
| CTNNA1 | RNF141 | 0.72783 | 11 | 0 | 11 |
| CTNNA1 | ARHGEF10L | 0.725563 | 11 | 0 | 11 |
| CTNNA1 | FBXW11 | 0.722054 | 11 | 0 | 11 |
| CTNNA1 | ECM1 | 0.72096 | 10 | 0 | 9 |
| CTNNA1 | CLCA4 | 0.720163 | 10 | 0 | 10 |
| CTNNA1 | AFF4 | 0.719704 | 12 | 0 | 11 |
| CTNNA1 | NPEPPS | 0.719172 | 11 | 0 | 11 |
| CTNNA1 | SPINK5 | 0.718729 | 10 | 0 | 9 |
| CTNNA1 | ENDOU | 0.718704 | 11 | 0 | 10 |
For details and further investigation, click here
