| Full name: COMM domain containing 6 | Alias Symbol: Acrg | ||
| Type: protein-coding gene | Cytoband: 13q22.2 | ||
| Entrez ID: 170622 | HGNC ID: HGNC:24015 | Ensembl Gene: ENSG00000188243 | OMIM ID: 612377 |
| Drug and gene relationship at DGIdb | |||
Expression of COMMD6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COMMD6 | 170622 | 225312_at | -0.4012 | 0.2245 | |
| GSE26886 | COMMD6 | 170622 | 225312_at | 1.1435 | 0.0000 | |
| GSE45670 | COMMD6 | 170622 | 225312_at | -0.2796 | 0.0541 | |
| GSE53622 | COMMD6 | 170622 | 89130 | -0.2578 | 0.0010 | |
| GSE53624 | COMMD6 | 170622 | 89130 | 0.1247 | 0.0527 | |
| GSE63941 | COMMD6 | 170622 | 225312_at | -0.2268 | 0.5226 | |
| GSE77861 | COMMD6 | 170622 | 225312_at | -0.2593 | 0.3237 | |
| GSE97050 | COMMD6 | 170622 | A_32_P114215 | -0.3888 | 0.1556 | |
| SRP007169 | COMMD6 | 170622 | RNAseq | -0.4456 | 0.2584 | |
| SRP008496 | COMMD6 | 170622 | RNAseq | -0.2585 | 0.2850 | |
| SRP064894 | COMMD6 | 170622 | RNAseq | 0.2337 | 0.5631 | |
| SRP133303 | COMMD6 | 170622 | RNAseq | 0.1822 | 0.4761 | |
| SRP159526 | COMMD6 | 170622 | RNAseq | -0.5639 | 0.0842 | |
| SRP193095 | COMMD6 | 170622 | RNAseq | -0.8482 | 0.0000 | |
| SRP219564 | COMMD6 | 170622 | RNAseq | -0.2646 | 0.4969 | |
| TCGA | COMMD6 | 170622 | RNAseq | -0.1036 | 0.0682 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by COMMD6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COMMD6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COMMD6 | 170622 | 3 | 11 | 16 | |
| GSE20123 | COMMD6 | 170622 | 3 | 10 | 17 | |
| GSE43470 | COMMD6 | 170622 | 4 | 10 | 29 | |
| GSE46452 | COMMD6 | 170622 | 0 | 32 | 27 | |
| GSE47630 | COMMD6 | 170622 | 3 | 27 | 10 | |
| GSE54993 | COMMD6 | 170622 | 11 | 3 | 56 | |
| GSE54994 | COMMD6 | 170622 | 3 | 14 | 36 | |
| GSE60625 | COMMD6 | 170622 | 0 | 3 | 8 | |
| GSE74703 | COMMD6 | 170622 | 3 | 8 | 25 | |
| GSE74704 | COMMD6 | 170622 | 1 | 9 | 10 | |
| TCGA | COMMD6 | 170622 | 12 | 33 | 51 |
Total number of gains: 43; Total number of losses: 160; Total Number of normals: 285.
Somatic mutations of COMMD6:
Generating mutation plots.
Highly correlated genes for COMMD6:
Showing top 20/492 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COMMD6 | HINT1 | 0.80515 | 3 | 0 | 3 |
| COMMD6 | ZNF358 | 0.768996 | 3 | 0 | 3 |
| COMMD6 | NAP1L1 | 0.761151 | 4 | 0 | 4 |
| COMMD6 | PLEKHB1 | 0.75099 | 3 | 0 | 3 |
| COMMD6 | XPC | 0.74872 | 3 | 0 | 3 |
| COMMD6 | MYADM | 0.744406 | 3 | 0 | 3 |
| COMMD6 | CDO1 | 0.743219 | 3 | 0 | 3 |
| COMMD6 | IDS | 0.742538 | 3 | 0 | 3 |
| COMMD6 | CPXM2 | 0.73881 | 3 | 0 | 3 |
| COMMD6 | TPM2 | 0.732792 | 4 | 0 | 4 |
| COMMD6 | ST6GALNAC6 | 0.731066 | 3 | 0 | 3 |
| COMMD6 | KLHL29 | 0.726782 | 3 | 0 | 3 |
| COMMD6 | TUBA1A | 0.723976 | 3 | 0 | 3 |
| COMMD6 | FOXN3 | 0.722046 | 4 | 0 | 3 |
| COMMD6 | SOBP | 0.721661 | 4 | 0 | 3 |
| COMMD6 | KIAA0753 | 0.715528 | 3 | 0 | 3 |
| COMMD6 | ABL1 | 0.714564 | 4 | 0 | 4 |
| COMMD6 | ZSCAN21 | 0.711797 | 3 | 0 | 3 |
| COMMD6 | C11orf96 | 0.7077 | 3 | 0 | 3 |
| COMMD6 | ATRX | 0.706845 | 4 | 0 | 3 |
For details and further investigation, click here
